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Table 1 EOC patient characteristics and the studied biomarkers (n = 161)

From: The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells

 

N

miR-509-3p

 

P

  

Low

High

 

Age

   

0.005

  < 52

67

24 (35.8)

43 (64.2)

 

  ≥ 52

94

55 (58.5)

39 (41.5)

 

Stage

   

 < 0.001

 I-II

73

19 (26.0)

54 (74.0)

 

 III-IV

88

60 (68.2)

28 (31.8)

 

Histology

   

0.002

 Serous

94

56 (59.6)

38 (40.4)

 

 Non-serous

67

23 (34.3)

44 (65.7)

 

  Mucinous

 

0 (0)

11 (100)

 

  Endometrioid

 

7 (63.6)

4 (36.4)

 

  Clear cell

 

16 (35.6)

29 (64.4)

 

Chemotherapy

136

  

0.188

 CR/PR

99

49 (49.5)

50 (50.5)

 

 SD/PD

37

23 (62.2)

14 (37.8)

 

PFI

   

0.286

  ≥ 6 m

124

58 (46.8)

66 (53.2)

 

  < 6 m

37

21 (56.8)

16 (43.2)

 

Death

   

0.010

 No

90

36 (40.0)

54 (60.0)

 

 Yes

71

43 (60.6)

28 (39.4)

 
  1. Data was presented as frequency (percentage)
  2. Data was analyzed by Chi-square test or Fisher’s exact test
  3. miR-509-3p level < 0.76 (low) and ≥ 0.76 (high); COL11A1 level < 1446.67 (low) and ≥ 1446.67 (high)
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Journal of Ovarian Research

ISSN: 1757-2215

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