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Table 2 The correlations between variables and M1 or M2 sites (n = 161)

From: The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells

   

M1

 

M2

 
  

n

No

Yes

P

No

Yes

P

miR-509-3p

Low

79

31 (39.2)

48 (60.8)

 < 0.001

37 (46.8)

42 (53.2)

 < 0.001

 

High

82

76 (92.7)

6 (7.3)

 

71 (86.6)

11 (13.4)

 

COL11A1

Low

73

55 (75.3)

18 (24.7)

0.030

53 (72.6)

20 (27.4)

0.174

 

High

88

52 (59.1)

36 (40.9)

 

55 (62.5)

33 (37.5)

 

Age

 < 52

67

50 (74.6)

17 (25.4)

0.064

52 (77.6)

15 (22.4)

0.016

 

 ≥ 52

94

57 (60.6)

37 (39.4)

 

56 (59.6)

38 (40.4)

 

Stage

Early

73

60 (82.2)

13 (17.8)

 < 0.001

54 (74.0)

19 (26.0)

0.090

 

Advanced

88

47 (53.4)

41 (46.6)

 

54 (61.4)

34 (38.6)

 

Histology

Serous

94

57 (60.6)

37 (39.4)

0.064

63 (67.0)

31 (33.0)

0.985

 

Non-serous

67

50 (74.6)

17 (25.4)

 

45 (67.2)

22 (32.8)

 

Chemotherapy

CR/PR

99

67 (67.7)

32 (32.3)

0.236

74 (74.7)

25 (25.3)

0.253

 

SD/PD

37

21 (56.8)

16 (43.2)

 

24 (64.9)

13 (35.1)

 

PFI

 ≥ 6 m

124

89 (71.8)

35 (28.2)

0.009

87 (70.2)

37 (29.8)

0.128

 

 < 6 m

37

18 (48.6)

19 (51.4)

 

21 (56.8)

16 (43.2)

 

Death

No

90

67 (74.4)

23 (25.6)

0.016

63 (70.0)

27 (30.0)

0.375

 

Yes

71

40 (56.3)

31 (43.7)

 

45 (63.4)

26 (36.6)

 
  1. Data was presented as frequency (percentage)
  2. Data was analyzed by Chi-square test or Fisher’s exact test
  3. miR-509-3p level < 0.76 (low) and ≥ 0.76 (high); COL11A1 level < 1446.67 (low) and ≥ 1446.67 (high)
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Journal of Ovarian Research

ISSN: 1757-2215

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