Fig. 1
From: Tumor metabolism rewiring in epithelial ovarian cancer
Metabolism rewiring of ovarian cancer cells. A shows the glucose metabolism alterations; (B) shows the lipid metabolism alterations; C shows the amino acid metabolism alterations. PDK-1, pyruvate dehydrogenase kinase-1; PDC, pyruvate dehydrogenase complex; KM2, pyruvate kinase M2; GLUT1, glucose transporter 1; LDHA, lactate dehydrogenase A; RTKs, receptor tyrosine kinases; FAs, fatty acids; PI3K, phosphoinositide 3-kinase; FASN, fatty acid synthase; SCDs, stearoyl CoA desaturases; mTORC1, mechanistic target of rapamycin complex 1; NEAAs, non-essential amino acids; TCA cycle, tricarboxylic acid cycle