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Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Exosomal circ_0008285 in follicle fluid regulates the lipid metabolism through the miR-4644/ LDLR axis in polycystic ovary syndrome

Fig. 7

miR-4644 targets LDLR to influence cholesterol metabolism. A The mRNA expression of Pparg, Pgc1 and Hmgcr in sh-NC and sh-circ_0008285 group. B & C The effects of circ_0008285 on LDL and free fatty acid production in sh-NC and sh-circ_0008285 group. DThe mRNA expression of Pparg, Pgc1 and Hmgcr in mimic-NC and mimic-miR-4644 group. E & F The effects of circ_0008285 on LDLand free fatty acid production in mimic-NC and mimic-miR-4644 group. G The mRNA expression of Pparg, Pgc1 and Hmgcr in sh-circ_0008285 + inhibitor-NC and sh-circ_0008285 + inhibitor-miR-4644 group. H & J The effects of circ_0008285 on LDL and free fatty acid production in sh-circ_0008285 + inhibitor-NC and sh-circ_0008285 + inhibitor-miR-4644. *P < 0.05, **P < 0.01

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Journal of Ovarian Research

ISSN: 1757-2215

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