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Table 3 Results of the subgroup analysis

From: Comparison of anti-Müllerian hormone and antral follicle count in the prediction of ovarian response: a systematic review and meta-analysis

Subgroup

Number (n)

Sensitivity (95%CI)

Specificity (95%CI)

PLR (95%CI)

NLR (95%CI)

DOR (95%CI)

Cut-off value

 AMH-poor response

  Overall

29

0.80 (0.74, 0.85)

0.81 (0.75, 0.85)

4.10 (3.20, 5.30)

0.25 (0.19, 0.32)

14.39 (10.26, 20.17)

   < 1.00 ng/ml 1

10

0.79 (0.69, 0.89)

0.84 (0.78, 0.89)

4.54 (3.55, 5.83)

0.35 (0.27, 0.44)

16.07 (11.53, 22.39)

   ≥ 1.00 ng/ml 0

12

0.82 (0.74, 0.90)

0.70 (0.62, 0.77)

2.59 (2.05, 3.28)

0.34 (0.24, 0.49)

8.13 (5.05, 13.09)

 AMH-high response

  Overall

13

0.81 (0.75, 0.86)

0.84 (0.77, 0.89)

5.00 (3.40, 7.30)

0.22 (0.16, 0.30)

22.67 (12.85, 40.00)

   < 4.00 ng/ml

8

0.75 (0.66, 0.83)

0.80 (0.72, 0.88)

3.63 (2.53, 5.19)

0.34 (0.24, 0.49)

11.83 (5.89, 23.73)

   ≥ 4.00 ng/ml

3

0.86 (0.76, 0.96)

0.88 (0.79, 0.97)

6.93 (2.56, 18.76)

0.17 (0.06, 0.52)

41.01 (5.36, 313.99)

 AFC-poor response

  Overall

15

0.73 (0.62, 0.83)

0.85 (0.78, 0.90)

4.26 (3.23, 5.62)

0.33 (0.22, 0.49)

13.93 (8.53, 22.74)

   < 6

7

0.61 (0.44, 0.79)

0.90 (0.84, 0.95)

5.18 (3.41, 7.85)

0.42 (0.24, 0.76)

14.06 (5.93, 33.34)

   ≥ 6

7

0.83 (0.72, 0.94)

0.79 (0.69, 0.88)

3.60 (2.53, 5.13)

0.27 (0.17, 0.44)

12.60 (6.31, 25.14)

 AFC-high response

  Overall

6

0.85 (0.77, 0.91)

0.83 (0.64, 0.94)

5.48 (2.50, 12.02)

0.18 (0.10, 0.32)

35.62 (10.06, 126.08)

   < 15

3

0.76 (0.69, 0.84)

0.64 (0.45, 0.82)

2.33 (1.41, 3.85)

0.35 (0.26, 0.46)

8.02 (5.32, 12.10)

   ≥ 15

3

0.89 (0.85, 0.93)

0.94 (0.89, 0.99)

13.61 (5.92, 31.31)

0.12 (0.07, 0.20)

126.72 (33.10, 485.15)

Definition of poor response (< 4 oocytes)

 AMH

11

0.78 (0.70, 0.85)

0.77 (0.69, 0.83)

3.24 (2.50, 4.21)

0.33 (0.24, 0.45)

11.27 (6.62, 19.19)

 AFC

9

0.81 (0.74, 0.87)

0.80 (0.73, 0.87)

4.00 (2.76, 5.79)

0.27 (0.19, 0.38)

16.76 (8.76, 30.18)

Sample size

 AMH-Poor response

   < 200

23

0.81 (0.75, 0.87)

0.80 (0.73, 0.86)

4.12 (3.00, 5.65)

0.23 (0.17, 0.32)

17.80 (10.54, 20.05)

   ≥ 200

6

0.74 (0.61, 0.84)

0.83 (0.75, 0.88)

4.26 (3.15, 5.78)

0.32 (0.22, 0.47)

13.45 (8.72, 20.74)

 AMH-High response

   < 200

8

0.83 (0.72, 0.91)

0.78 (0.65, 0.87)

3.79 (2.29, 6.26)

0.21 (0.12, 0.37)

17.62 (7.50, 41.44)

   ≥ 200

11

0.81 (0.73, 0.87)

0.87 (0.79, 0.92)

6.12 (3.63, 10.33)

0.22 (0.15, 0.33)

27.66 (12.24, 62.49)

 AFC-Poor response

   < 200

10

0.77 (0.60, 0.88)

0.85 (0.76, 0.91)

5.27 (3.16, 8.79)

0.27 (0.15, 0.50)

19.23 (7.82, 47.30)

   ≥ 200

5

0.69 (0.50, 0.84)

0.84 (0.73, 0.91)

4.33 (2.86, 6.53)

0.36 (0.22, 0.59)

11.87 (6.83, 20.63)

 AFC-high response

   < 200

2

0.89 (0.78, 0.99)

0.70 (0.35, 0.99)

-

-

-

   ≥ 200

4

0.84 (0.76, 0.92)

0.88 (0.75, 0.99)

6.70 (2.57, 17.45)

0.17 (0.08, 0.37)

39.11 (7.15, 213.98)

  1. PLR Positive likelihood ratio, NLR Negative likelihood ratio, DOR Diagnostic odds ratio