Subgroup | Number (n) | Sensitivity (95%CI) | Specificity (95%CI) | PLR (95%CI) | NLR (95%CI) | DOR (95%CI) |
---|---|---|---|---|---|---|
Cut-off value | ||||||
AMH-poor response | ||||||
Overall | 29 | 0.80 (0.74, 0.85) | 0.81 (0.75, 0.85) | 4.10 (3.20, 5.30) | 0.25 (0.19, 0.32) | 14.39 (10.26, 20.17) |
< 1.00 ng/ml 1 | 10 | 0.79 (0.69, 0.89) | 0.84 (0.78, 0.89) | 4.54 (3.55, 5.83) | 0.35 (0.27, 0.44) | 16.07 (11.53, 22.39) |
≥ 1.00 ng/ml 0 | 12 | 0.82 (0.74, 0.90) | 0.70 (0.62, 0.77) | 2.59 (2.05, 3.28) | 0.34 (0.24, 0.49) | 8.13 (5.05, 13.09) |
AMH-high response | ||||||
Overall | 13 | 0.81 (0.75, 0.86) | 0.84 (0.77, 0.89) | 5.00 (3.40, 7.30) | 0.22 (0.16, 0.30) | 22.67 (12.85, 40.00) |
< 4.00 ng/ml | 8 | 0.75 (0.66, 0.83) | 0.80 (0.72, 0.88) | 3.63 (2.53, 5.19) | 0.34 (0.24, 0.49) | 11.83 (5.89, 23.73) |
≥ 4.00 ng/ml | 3 | 0.86 (0.76, 0.96) | 0.88 (0.79, 0.97) | 6.93 (2.56, 18.76) | 0.17 (0.06, 0.52) | 41.01 (5.36, 313.99) |
AFC-poor response | ||||||
Overall | 15 | 0.73 (0.62, 0.83) | 0.85 (0.78, 0.90) | 4.26 (3.23, 5.62) | 0.33 (0.22, 0.49) | 13.93 (8.53, 22.74) |
< 6 | 7 | 0.61 (0.44, 0.79) | 0.90 (0.84, 0.95) | 5.18 (3.41, 7.85) | 0.42 (0.24, 0.76) | 14.06 (5.93, 33.34) |
≥ 6 | 7 | 0.83 (0.72, 0.94) | 0.79 (0.69, 0.88) | 3.60 (2.53, 5.13) | 0.27 (0.17, 0.44) | 12.60 (6.31, 25.14) |
AFC-high response | ||||||
Overall | 6 | 0.85 (0.77, 0.91) | 0.83 (0.64, 0.94) | 5.48 (2.50, 12.02) | 0.18 (0.10, 0.32) | 35.62 (10.06, 126.08) |
< 15 | 3 | 0.76 (0.69, 0.84) | 0.64 (0.45, 0.82) | 2.33 (1.41, 3.85) | 0.35 (0.26, 0.46) | 8.02 (5.32, 12.10) |
≥ 15 | 3 | 0.89 (0.85, 0.93) | 0.94 (0.89, 0.99) | 13.61 (5.92, 31.31) | 0.12 (0.07, 0.20) | 126.72 (33.10, 485.15) |
Definition of poor response (< 4 oocytes) | ||||||
AMH | 11 | 0.78 (0.70, 0.85) | 0.77 (0.69, 0.83) | 3.24 (2.50, 4.21) | 0.33 (0.24, 0.45) | 11.27 (6.62, 19.19) |
AFC | 9 | 0.81 (0.74, 0.87) | 0.80 (0.73, 0.87) | 4.00 (2.76, 5.79) | 0.27 (0.19, 0.38) | 16.76 (8.76, 30.18) |
Sample size | ||||||
AMH-Poor response | ||||||
< 200 | 23 | 0.81 (0.75, 0.87) | 0.80 (0.73, 0.86) | 4.12 (3.00, 5.65) | 0.23 (0.17, 0.32) | 17.80 (10.54, 20.05) |
≥ 200 | 6 | 0.74 (0.61, 0.84) | 0.83 (0.75, 0.88) | 4.26 (3.15, 5.78) | 0.32 (0.22, 0.47) | 13.45 (8.72, 20.74) |
AMH-High response | ||||||
< 200 | 8 | 0.83 (0.72, 0.91) | 0.78 (0.65, 0.87) | 3.79 (2.29, 6.26) | 0.21 (0.12, 0.37) | 17.62 (7.50, 41.44) |
≥ 200 | 11 | 0.81 (0.73, 0.87) | 0.87 (0.79, 0.92) | 6.12 (3.63, 10.33) | 0.22 (0.15, 0.33) | 27.66 (12.24, 62.49) |
AFC-Poor response | ||||||
< 200 | 10 | 0.77 (0.60, 0.88) | 0.85 (0.76, 0.91) | 5.27 (3.16, 8.79) | 0.27 (0.15, 0.50) | 19.23 (7.82, 47.30) |
≥ 200 | 5 | 0.69 (0.50, 0.84) | 0.84 (0.73, 0.91) | 4.33 (2.86, 6.53) | 0.36 (0.22, 0.59) | 11.87 (6.83, 20.63) |
AFC-high response | ||||||
< 200 | 2 | 0.89 (0.78, 0.99) | 0.70 (0.35, 0.99) | - | - | - |
≥ 200 | 4 | 0.84 (0.76, 0.92) | 0.88 (0.75, 0.99) | 6.70 (2.57, 17.45) | 0.17 (0.08, 0.37) | 39.11 (7.15, 213.98) |