Fig. 3

DK prominently improves impaired fertility in the PCOS mice. The mice were divided into four groups (OIL, OIL + DK, DHEA, DHEA + DK). (A) Schematic diagram of early treatment strategies. (B, C) DK can effectively improve the reproductive abnormalities of PCOS mice. (D) The mice were tested for ovulation on the day of vaginal plug. (E) DK significantly increased the number of corpuses luteum and decreased the number of cystic follicles in PCOS mice. # Indicates cystic follicles. * Indicates Corpus luteum. (F, G) The statistics of the corpus luteum and the follicles, respectively. All data were analyzed by one-way ANOVA with Tukey’s post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001,**** P < 0.0001. n = 3 per group