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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Dingkun pill alleviates metabolic abnormalities in polycystic ovary syndrome through brown adipose tissue activation

Fig. 6

DK treatment in PCOS mice activate the brown adipose metabolism and thermogenesis. (A) Heat map shows the expression level of differentially upregulated genes in OIL, DHEA and DHEA + DK groups. (B, C) B and C represent GO and KEGG analysis of the differentially expressed genes in DHEA and DHEA + DK groups, respectively. P values were determined by two-tailed Wilcoxon rank-sum test. (D, E, F) QRT-PCR analyzes the mRNA expression of lipid metabolism related Acox1, Mgll, Pnpla2 among OIL, OIL + DK, DHEA and DHEA + DK groups. (G, H) Lipid droplet content among OIL, OIL + DK, DHEA and DHEA + DK groups. All data were analyzed by one-way ANOVA with Tukey’s post hoc test. *P < 0.05, **P < 0.01, n = 3 per group

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Journal of Ovarian Research

ISSN: 1757-2215

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