Table 1 Patient characteristics (N = 74)
Age | median (range) | 46 (29–64) | |
|---|---|---|---|
Mutated genes | BRCA1 | 43 | 58.1% |
BRCA2 | 26 | 35.1% | |
ATM | 1 | 1.4% | |
BRIP1 | 1 | 1.4% | |
PALB2 | 1 | 1.4% | |
MLH1 | 1 | 1.4% | |
TP53 | 1 | 1.4% | |
Personal history | Breast cancer | 45 | 60.8% |
Gastric cancer and breast cancer | 1 | 1.4% | |
Ovarian sex cord-stromal tumor | 1 | 1.4% | |
No | 27 | 36.5% | |
Family history | Yes | 57 | 77.0% |
No | 17 | 23.0% | |
CA125 | median (range) | 11.0 (3.9–124) | |
HE4 | median (range) | 45.7 (30.5–79.6) | |
Surgical procedure | Staging/debulking surgery | 3 | 4.1% |
RRSO | 54 | 73.0% | |
RRSO + hysterectomy | 17 | 23.0% | |
Pathology | Cancer | 3 | 4.1% |
STIC | 1 | 1.4% | |
STIL | 5 | 6.8% | |
p53 signature | 24 | 32.4% | |
Benign | 41 | 55.4% | |