Fig. 7

The expression of DEGs and differentially expressed ncRNAs in hGL and KGN. A Venn diagram of Hub genes, MCODE cluster genes, 11 overlapping genes of three mRNA databases, and mRNAs in ceRNA network. The mRNA expression levels of MVD (n = 113) (B), PNPLA3 (n = 124) (C), hsa-miR-205-5p (n = 26) in hGL (D). KGN were transfected with hsa-miR-205-5p mimics (100nM), and the expression of MVD and PNPLA3 were examined by RT–PCR and western blot respectively (E-I). The mRNA expression levels of SAA2 (n = 44) (J), SCGB2A2 (n = 29) (K), SLC30A10 (n = 27) (L), UGT2BF (n = 31) (M), hsa-circ-0020555 (n = 45) (N), hsa-circ-0027651 (n = 45) (O), hsa-circ-0086809 (n = 39) (P), hsa-circ-0118448 (n = 46) in hGL (Q)