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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: TFE3 nuclear expression as a novel biomarker of ovarian sclerosing stromal tumors and associated with its histological morphology

Fig. 2

Expression of TFE3 in different types of sex cord stromal tumors. The cut surfaces of SST were solid with yellow (A). The cytoplasm of most cells in the lobules was rich, eosinophilic and granular (black arrows) (B). Cytoplasm-rich cells express TFE3 (C). The cut surface of the adult granulosa cell tumor is nodular and light yellow (D). Granulosa cells usually have scanty cytoplasm and pale, uniform, angular to oval, often grooved nuclei that are typically arranged haphazardly to each other, and typical Call-Exner bodies can be seen (red circles) (E). TFE3 is not expressed in AGCT (F). Thecoma. The typical sectioned surface of a thecoma showing a yellow appearance (G). Thecoma. A high-power view shows the characteristic appreciable pale gray cytoplasm, ill-defined cytoplasmic membranes, and scattered collagen bundles (H). TFE3 is not expressed in the tumor cells of thecoma (I). Microcystic stromal tumor. The sectioned surface showing a solid, yellow appearance (J). Microcystic stromal tumor. Characteristic small cysts and hyaline plaques are seen (K). The tumor cells do not express TFE3 (L)

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