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Table 3 Results of the Base-Case Analysis

From: The cost-effectiveness analysis of maintenance olaparib plus Bevacizumab in patients with advanced ovarian cancer: based on the final survival results from PAOLA-1 trial

Treatment

Total cost $

LYs

ICER $/LY a

QALYs

ICER $/QALY b

Overall Patients

Bevacizumab

329,087

6.46

NA

5.23

NA

Olaparib plus bevacizumab

622,743

8.42

136,218

7.08

158,729

Patients with BRCA Mutations

Bevacizumab

440,453

6.96

NA

5.58

NA

Olaparib plus bevacizumab

706,121

10.89

66,120

8.92

79,434

Patients with HRD positive

Bevacizumab

374,452

7.32

NA

5.91

NA

Olaparib plus bevacizumab

617,198

9.36

117,747

7.62

141,636

Patients with HRD positive without BRCA Mutations

Bevacizumab

332,850

6.38

NA

5.16

NA

Olaparib plus bevacizumab

526,642

7.52

169,733

6.13

200,595

  1. a Compared to olaparib plus bevacizumab ($/LY).
  2. b Compared to olaparib plus bevacizumab ($/QALY).
  3. Abbreviation: ICER, incremental cost-effectiveness ratio; LY, life-year; QALY, quality-adjusted life-year; BRCA, breast cancer susceptibility genes; HRD, homologous recombination deficiency