Mitigation of letrozole induced polycystic ovarian syndrome associated inflammatory response and endocrinal dysfunction by Vitex negundo seeds

Table 1 Effect of Vitex negundo extract on body weight and organosomatic indices parameters in letrozole induced PCOS rat

Group	Control	PC	LTZ	LTZ + VNE
Changes in body weight (gm %)	116.31 ± 1.81	112.97 ± 2.22 ###	144.48 ± 4.17 ***	117.01 ± 2.47 ###
Ovarian index (gm%)	0.056 ± 0.002	0.057 ± 0.001	0.047 ± 0.083	0.039 ± 0.003
Uterine index (gm%)	0.2263 ± 0.02	0.1834 ± 0.010##	0.0754 ± 0.013 ***	0.1045 ± 0.015

Effect of Vitex negundo extract on body weight and organosomatic indices in letrozole induced PCOS rat. Data presented as the Mean ± S.E.M. (n = 6), evaluated by ANOVA followed by the post hoc Tukey's test
*p<0.05, **p<0.01, ***p<0.001 vs. control; #p<0.05, ##p<0.01, ###p<0.001 vs. PCOS group

ISSN: 1757-2215