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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: LncRNA SNHG12 promotes cell proliferation and inhibits apoptosis of granulosa cells in polycystic ovarian syndrome by sponging miR-129 and miR-125b

Fig. 2

Overexpressing and silencing the expression of lncRNA SNHG12 influenced the body weight, ovary weight, gonadal hormone, miR-129, miR-125b expressions, and pathological changes in PCOS rats. Body weight and ovary weight of rats in each group, n = 5 in each group; ELISA was used for testing the T, E2, P, LH and FSH levels of the rats in each group, the ratio of LH/FSH was calculated, n = 5 in each group; qRT-PCR was used for testing lncRNA SNHG12, miR-129, and miR-125b mRNA expressions of rats in each group, n = 3 in each group; The histomorphology of ovary tissues in rats was observed by hematoxylin-eosin staining (magnification × 40, 200, 400); ▲P < 0.05, ▲▲P < 0.01 vs. control group; ★P < 0.05, ★★P < 0.01 vs. DHEA group; P < 0.05, ##P < 0.01 vs. NC group

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