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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2

Fig. 4

siCLCA2 decreased the cell apoptosis induced by the TP63-mut (A) The RT-qPCR data showed a significant decrease in CLCA2 expression upon treatment with siCLCA2–1 and siCLCA2–2 (p < 0.01). (B-C) The western immunoblotting assay revealed a significant decrease in CLCA2 expression following treatment with siCLCA2–2. (D-E) The Annexin-V assay showed that siCLCA2 inhibited cell apoptosis induced by TP63-mut

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