Pre-operative plasma VEGF-C levels portend recurrence in epithelial ovarian cancer patients and is a bankable prognostic marker even in the initial assessment of a patient

Table 3 Association of test factors with clinicopathological factors

Test Factors/Clinico-pathological factors	VEGF-C plasma levels	VEGF-C tissue expression	COX-2 tissue expression	eNOS tissue expression	NOx plasma levels	Ki-67 tissue expression
FIGO stage (I, II Vs III IV)	< 0.001	0.251	< 0.001	0.175	0.271	0.006
Grade (low Vs high)	< 0.001	0.209	< 0.001	0.329	0.638	0.034
Malignancy (Malignant Vs benign/controls)	< 0.001	0.201	< 0.001	0.060	0.361	< 0.001
Histopathology (Serous Vs Others)	0.268	0.541	< 0.001	0.574	0.481	0.601
Bilateral-affliction (Presence Vs Absence)	0.001	0.219	0.012	0.624	0.059	< 0.001
Pre-opCA125 levels (Elevated Vs Normal)	0.004	0.875	< 0.001	0.879	0.502	< 0.001
Ascites (Presence Vs Absence)	0.037	0.758	0.006	0.537	0.086	< 0.001
Residual disease (< 1 Vs > 1)	0.174	0.862	0.142	0.710	0.860	0.002
Recurrence (Presence Vs Absence)	< 0.001	0.560	< 0.001	0.797	0.814	0.276

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