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Table 1 Clinicopathological characteristics of patients in the entire cohort

From: Subsequent management and outcomes after first-line PARP inhibitors progression in ovarian cancer patients

Clinical Characteristics

n

%

N

44

Median age (Range)

55 (29–76)

Age at diagnosis (y)

  

< 50

13

29.5

≥50

31

70.5

Tumor size (cm)

 

<5

10

22.7

≥ 5

34

77.3

Primary tumor location

  

Ovary

43

97.7

Fallopian tube

1

2.3

Histology

  

Serous

43

97.7

Clear cell cancer

1

2.3

FIGO Stage

 

I

0

0.0

II

1

2.3

III

31

70.5

IV

12

27.3

Neoadjuvant chemotherapy

 

Yes

30

68.2

No

14

31.8

Postoperative residual disease status

 

Optimal (R0/R1)

38

86.4

Suboptimal (≥ R1)

6

13.6

PARPi received

 

Fluzoparib

3

6.8

Olaprib

17

38.6

Niraparib

24

54.5

HRR status

 

BRCA1 mt

8

18.2

BRCA2 mt

4

9.1

Non-BRCA HRR mt

5

11.4

WT

27

61.4

First recurrence

 

Platinum-sensitive recurrence

37

84.1

Platinum-resistant recurrence

7

15.9

  1. Abbreviations Mt, mutation; WT, wild-type; FIGO, International Federation of Gynecology and Obstetrics; NA, not available