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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway

Fig. 4

hUMSC-exos alleviated CTX-induced KGN cell apoptosis. A Cell proliferation detected by EDU after co-culturing KGN cells treated with hUMSC-exos and CTX for 24 h and 48 h. (Magnification 100×. Red: EDU. Blue: DAPI.) B KGN cell death detected by Hoechst/PI after co-culturing KGN cells treated with hUMSC-exos and CTX for 24 h and 48 h. (Magnification 100×. Red: DAPI. Blue: Hoechst.) C Statistical results from Fig. 4A and B. **P < 0.01, ***P < 0.001, ****P < 0.001

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