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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway

Fig. 5

hUMSC-exos alleviated CTX-induced ferroptosis in KGN cells. A Comparison of ROS levels in Nc group, POI group, POI + Exos group, and POI + Exos + ML385 group. B Detection of Fe2 + in Nc group, POI group, POI + Exos group, and POI + Exos + ML385 group by FeRhoNoxTM − 1 staining. C Statistical analysis results of ROS detection and FeRhoNoxTM − 1 staining. (**P < 0.01, ***P < 0.001, ****P < 0.001.)

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