Fig. 1
From: CAPN2 correlates with insulin resistance states in PCOS as evidenced by multi-dataset analysis
WGCNA Reveals Key Gene Modules Linked to Insulin Resistance in PCOS. (A) Plots scale-free fit index against mean connectivity to select the optimal soft-thresholding power, ensuring network accuracy and relevance. (B) The Module-Tree displays merging of similar modules at specific cut heights, simplifying the network. (C) Hierarchical clustering of gene modules is shown, with unique color names representing different modules, highlighting their relationships and potential functions. (D) An eigengene adjacency heatmap reveals correlations among module eigengenes, showing their network integration. (E) Combines sample clustering with a trait heatmap, linking gene module patterns to insulin resistance scores and identifying modules with notable correlations. (F) Details module-trait relationships with correlation coefficients and P-values, pinpointing modules significantly linked to insulin resistance, guiding focused therapeutic investigation