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Table 1 Comparative Clinical and Hormonal Characteristics of PCOS and Normal Subjects

From: CAPN2 correlates with insulin resistance states in PCOS as evidenced by multi-dataset analysis

 

Normal

n = 12

PCOS

n = 12

P-value

Infertility Duration (years)

2.9 ± 1.7

4.3 ± 1.8

0.417

Age (years)

33.6 ± 3.8

28.3 ± 3

0.532

BMI

21.1 ± 2.9

23.5 ± 1.6

0.016

Age at Menarche

13

13

-

Menstrual Cycle Duration (days)

28–31

irregular

-

Basal FSH (mIU/mL)

6.6 ± 0.8

6.2 ± 0.7

0.444

Basal LH (mIU/mL)

6.1 ± 1.3

10.1 ± 0.7

0.108

Basal Prolactin (mIU/L)

345.8 ± 170.7

219.8 ± 254

0.238

Basal Estradiol (pg/mL)

102.2 ± 61.8

95.5 ± 55.8

0.994

Basal Progesterone (nmol/L)

1.1 ± 0.9

0.6 ± 0.4

0.265

Basal Testosterone (nmol/L)

0.8 ± 0.5

1 ± 0.6

0.612

AMH (ng/mL)

7.5 ± 1.6

12.9 ± 3.6

0.053

AFC

< 15

> 25

-

FSH on COS Initial Day (mIU/mL)

5.7 ± 1.9

6.2 ± 1.1

0.089

LH on COS Initial Day (mIU/mL)

4.9 ± 2.6

9.7 ± 3.3

0.758

Estradiol on COS Initial Day (E2) (pg/mL)

88.8 ± 68.3

94 ± 63

0.747

Initial Dosage of COS (IU)

158.3 ± 35.5

133.3 ± 17.1

0.038

COS Duration (days)

8.9 ± 1.4

9.3 ± 2.1

0.335

Gonadotropin Dosage within COS (IU)

1497.9 ± 472.6

1252.1 ± 391.7

0.38

  1. COS: Controlled Ovarian Stimulation; FSH: Follicle Stimulating Hormone; LH: Luteinizing Hormone; AMH: Anti-Müllerian Hormone; AFC: Antral Follicle Count; Gn: Gonadotropin