From: Cardiovascular mortality risk in patients with ovarian cancer: a population-based study
Characteristics | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Adjusted HR (95%CI) | p-value | Adjusted HR (95%CI) | p-value | |
Age | ||||
01-14 years | Reference | |||
15-29 years | 2.69 (1.84-3.92) | <0.001 | 2.34 (1.61-3.42) | <0.001 |
30-44 years | 6.72 (4.66-9.69) | <0.001 | 4.20 (2.91-60.07) | <0.001 |
45-49 years | 10.81 (7.51-15.56) | <0.001 | 5.52 (3.82-7.96) | <0.001 |
60-74 years | 16.34 (11.35-23.51) | <0.001 | 7.02 (4.87-10.13) | <0.001 |
75+ years | 33.81 (23.49-48.68) | <0.001 | 11.49 (7.96-16.58) | <0.001 |
Race | ||||
White | Reference | |||
Black | 1.24 (1.21-1.28) | <0.001 | 1.25 (1.21-1.29) | <0.001 |
Asian or Pacific Islander | 0.70 (0.68-0.73) | <0.001 | 0.91 (0.88-0.94) | <0.001 |
American Indian/Alaska Native | 1.06 (0.96-1.18) | 0.236 | 1.17 (1.05-1.30) | 0.003 |
Chemotherapy | ||||
No | Reference | |||
Yes | 1.10 (1.08-1.12) | <0.001 | 0.67 (0.65-0.68) | <0.001 |
Summary stage | ||||
Distant | Reference | |||
Localized | 0.13 (0.13-0.14) | <0.001 | 0.16 (0.16-0.17) | <0.001 |
Regional | 0.29 (0.28-0.30) | <0.001 | 0.36 (0.35-0.37) | <0.001 |
Unknown/unstaged | 0.74 (0.71-0.78) | <0.001 | 0.47 (0.45-0.50) | <0.001 |
Surgery | ||||
Cytoreductive surgery | Reference | |||
No | 3.27 (3.19-3.35) | <0.001 | 2.71 (2.64-2.78) | <0.001 |
Other | 1.03 (0.95-1.11) | 0.525 | 1.28 (1.18-1.39) | <0.001 |
Palliative surgery | 0.44 (0.43-0.45) | <0.001 | 0.81 (0.79-0.83) | <0.001 |
ICD-O-3 | Reference | |||
Adenocarcinoma | Reference | |||
Epithelial carcinoma | 1.74 (1.68-1.81) | <0.001 | 1.19 (1.14-1.24) | <0.001 |
Other types | 0.41 (0.39-0.43) | <0.001 | 0.73 (0.69-0.76) | <0.001 |
Sarcoma | 1.82 (1.75-1.89) | <0.001 | 1.64 (1.57-1.70) | <0.001 |
Year of diagnose | ||||
2000-2005 | Reference | |||
2006-2011 | 0.93 (0.91-0.95) | <0.001 | 0.95 (0.93-0.97) | <0.001 |
2012-2017 | 0.87 (0.85-0.89) | <0.001 | 0.87 (0.85-0.89) | <0.001 |