Taylor AE: Polycystic ovary syndrome. Endocrinol Metab Clin North Am 1998, 27: 877–902. ix 10.1016/S0889-8529(05)70045-1
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome Fertil Steril 2004, 81: 19–25.
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Hum Reprod 2004, 19: 41–47.
Burghen GA, Givens JR, Kitabchi AE: Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. J Clin Endocrinol Metab 1980, 50: 113–116. 10.1210/jcem-50-1-113
Baillargeon JP, Carpentier A: Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity. Fertil Steril 2007, 88: 886–893. 10.1016/j.fertnstert.2006.12.055
Baptiste CG, Battista MC, Trottier A, Baillargeon JP: Insulin and hyperandrogenism in women with polycystic ovary syndrome. J Steroid Biochem Mol Biol 2010, 122: 42–52. 10.1016/j.jsbmb.2009.12.010
Ehrmann DA: Insulin-lowering therapeutic modalities for polycystic ovary syndrome. Endocrinol Metab Clin North Am 1999, 28: 423–438. viii 10.1016/S0889-8529(05)70078-5
Hasegawa I, Murakawa H, Suzuki M, Yamamoto Y, Kurabayashi T, Tanaka K: Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome. Fertil Steril 1999, 71: 323–327. 10.1016/S0015-0282(98)00454-3
Nestler JE, Jakubowicz DJ, Reamer P, Gunn RD, Allan G: Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. N Engl J Med 1999, 340: 1314–1320. 10.1056/NEJM199904293401703
Gerli S, Mignosa M, Di Renzo GC: Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci 2003, 7: 151–159.
Ng EH, Wat NM, Ho PC: Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene-resistant polycystic ovaries: a randomized, double-blinded placebo-controlled trial. Hum Reprod 2001, 16: 1625–1631. 10.1093/humrep/16.8.1625
Huang LC, Fonteles MC, Houston DB, Zhang C, Larner J: Chiroinositol deficiency and insulin resistance. III. Acute glycogenic and hypoglycemic effects of two inositol phosphoglycan insulin mediators in normal and streptozotocin-diabetic rats in vivo. Endocrinology 1993, 132: 652–657. 10.1210/en.132.2.652
Papaleo E, Unfer V, Baillargeon JP, De Santis L, Fusi F, Brigante C, Marelli G, Cino I, Redaelli A, Ferrari A: Myo-inositol in patients with polycystic ovary syndrome: a novel method for ovulation induction. Gynecol Endocrinol 2007, 23: 700–703. 10.1080/09513590701672405
Larner J: D-chiro-inositol–its functional role in insulin action and its deficit in insulin resistance. Int J Exp Diabetes Res 2002, 3: 47–60. 10.1080/15604280212528
Chiu TT, Rogers MS, Law EL, Briton-Jones CM, Cheung LP, Haines CJ: Follicular fluid and serum concentrations of myo-inositol in patients undergoing IVF: relationship with oocyte quality. Hum Reprod 2002, 17: 1591–1596. 10.1093/humrep/17.6.1591
Papaleo E, Unfer V, Baillargeon JP, Chiu TT: Contribution of myo-inositol to reproduction. Eur J Obstet Gynecol Reprod Biol 2009, 147: 120–123. 10.1016/j.ejogrb.2009.09.008
Papaleo E, Unfer V, Baillargeon JP, Fusi F, Occhi F, De Santis L: Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial. Fertil Steril 2009, 91: 1750–1754. 10.1016/j.fertnstert.2008.01.088
Raffone E, Rizzo P, Benedetto V: Insulin sensitiser agents alone and in co-treatment with r-FSH for ovulation induction in PCOS women. Gynecol Endocrinol 2010, 26: 275–280. 10.3109/09513590903366996
Unfer V, Carlomagno G, Rizzo P, Raffone E, Roseff S: Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial. Eur Rev Med Pharmacol Sci 2011, 15: 452–457.
Borini A, Sciajno R, Bianchi V, Sereni E, Flamigni C, Coticchio G: Clinical outcome of oocyte cryopreservation after slow cooling with a protocol utilizing a high sucrose concentration. Hum Reprod 2006, 21: 512–517.
Van de Velde H, Nagy ZP, Joris H, De Vos A, Van Steirteghem AC: Effects of different hyaluronidase concentrations and mechanical procedures for cumulus cell removal on the outcome of intracytoplasmic sperm injection. Hum Reprod 1997, 12: 2246–2250. 10.1093/humrep/12.10.2246
De Santis L, Cino I, Rabellotti E, Papaleo E, Calzi F, Fusi FM, Brigante C, Ferrari A: Oocyte cryopreservation: clinical outcome of slow-cooling protocols differing in sucrose concentration. Reprod Biomed Online 2007, 14: 57–63. 10.1016/S1472-6483(10)60764-X
Arya BK, Haq AU, Chaudhury K: Oocyte quality reflected by follicular fluid analysis in poly cystic ovary syndrome (PCOS): A hypothesis based on intermediates of energy metabolism. Med Hypotheses 2012, 78: 475–478. 10.1016/j.mehy.2012.01.009
Ma X, Fan L, Meng Y, Hou Z, Mao YD, Wang W, Ding W, Liu JY: Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome. Mol Hum Reprod 2007, 13: 527–535. 10.1093/molehr/gam036
Larner J, Craig JW: Urinary myo-inositol-to-chiro-inositol ratios and insulin resistance. Diabetes Care 1996, 19: 76–78.
Asplin I, Galasko G, Larner J: chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects. Proc Natl Acad Sci U S A 1993, 90: 5924–5928. 10.1073/pnas.90.13.5924
Harwood K, Vuguin P, DiMartino-Nardi J: Current approaches to the diagnosis and treatment of polycystic ovarian syndrome in youth. Horm Res 2007, 68: 209–217.
Matalliotakis I, Kourtis A, Koukoura O, Panidis D: Polycystic ovary syndrome: etiology and pathogenesis. Arch Gynecol Obstet 2006, 274: 187–197. 10.1007/s00404-006-0171-x
Carlomagno G, Unfer V, Roseff S: The D-chiro-inositol paradox in the ovary. Fertil Steril 2011, 95: 2515–2516. 10.1016/j.fertnstert.2011.05.027
Ciotta L, Stracquadanio M, Pagano I, Carbonaro A, Palumbo M, Gulino F: Effects of myo-inositol supplementation on oocyte's quality in PCOS patients: a double blind trial. Eur Rev Med Pharmacol Sci 2011, 15: 509–514.
Cheang KI, Baillargeon JP, Essah PA, Ostlund RE, Apridonize T, Islam L, Nestler JE: Insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome. Metabolism 2008, 57: 1390–1397. 10.1016/j.metabol.2008.05.008
Palomba S, Falbo A, Di Cello A, Cappiello F, Tolino A, Zullo F: Does metformin affect the ovarian response to gonadotropins for in vitro fertilization treatment in patients with polycystic ovary syndrome and reduced ovarian reserve? A randomized controlled trial. Fertil Steril 2011, 96: 1128–1133. 10.1016/j.fertnstert.2011.08.020
Baillargeon JP, Iuorno MJ, Jakubowicz DJ, Apridonidze T, He N, Nestler JE: Metformin therapy increases insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2004, 89: 242–249. 10.1210/jc.2003-030437