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Figure 8 | Journal of Ovarian Research

Figure 8

From: Polycystic ovarian syndrome is accompanied by repression of gene signatures associated with biosynthesis and metabolism of steroids, cholesterol and lipids

Figure 8

The expression pattern of genes involving in sex steroid biosynthesis pathway in DHT-treated rat ovaries. (A) A modified steroid biosynthesis pathway from [53]. The intermediate and final products performed by dysregulated genes in DHT-treated ovaries are indicated in white box while the number in red or green circle corresponds the genes (enzymes) indicated in Figure B. (B) The heatmap displaying the expression pattern of repressed and activated genes involving in steroid biosynthesis in DHT compared to CTL. FC indicates the average fold change gene expression reduction or activation in DHT compared to CTL. P value: the significant levels.

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