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Table 1 The expression of premature ovarian failure is up-regulated, and the expression of differentially expressed genes is down-regulated after hUC-MSCs treatment

From: Effects of single and multiple transplantations of human umbilical cord mesenchymal stem cells on the recovery of ovarian function in the treatment of premature ovarian failure in mice

Name POF/SHAM UP MSCs/POF DOWN MSCs/SHAM
Fold change values P value Fold change values P value Fold change values P value
mmu-miR-101c 1.93 0.024 -2.11 0.040 -0.19 0.349
mmu-miR-1892 1.99 0.030 -1.36 0.049 0.64 0.057
mmu-miR-1894-3p 1.52 0.045 -1.03 0.020 0.49 0.141
mmu-miR-3070–2-3p 5.03 0.023 -5.62 0.018 -0.59 0.162
mmu-miR-3072-5p 2.97 0.020 -1.99 0.039 0.98 0.101
mmu-miR-3102-5p.2-5p 3.35 0.029 -2.39 0.032 0.96 0.119
mmu-miR-328-5p 1.56 0.042 -1.58 0.042 -0.01 0.904
mmu-miR-3547-5p 1.53 0.028 -1.05 0.049 0.48 0.138
mmu-miR-363-5p 2.56 0.044 -6.65 0.016 -4.09 0.023
mmu-miR-374b-5p 0.32 0.024 -0.60 0.007 -0.28 0.027
mmu-miR-374c-5p 0.40 0.042 -0.86 0.018 -0.46 0.016
mmu-miR-5122 1.05 0.033 -0.99 0.044 0.06 0.545
mmu-miR-652-5p 1.01 0.015 -0.99 0.020 0.03 0.610
mmu-miR-6965-5p 4.40 0.010 -2.80 0.017 1.60 0.021
mmu-miR-7088-5p 1.28 0.040 -0.61 0.033 0.67 0.076
mmu-miR-7235-5p 0.85 0.041 -0.66 0.042 0.19 0.192
mmu-miR-7648-5p 4.73 0.023 -2.80 0.041 1.94 0.079
mmu-miR-8110 1.51 0.017 -0.86 0.033 0.65 0.020
apoptosis-associated tyrosine kinase (Aatk) 1.10 0.022 -1.66 0.002 -0.55 0.248
apolipoprotein F (ApoF) 0.91 0.051 -2.27 0.002 -1.38 0.011
beta-1,3-N-acetylgalactosaminyltransferase 1 (B3galnt1) 0.73 0.099 -0.82 0.071 -0.04 0.914
apoptosis repeat containing 5 (Birc5) 0.74 0.090 -0.86 0.051 -0.13 0.740
calmodulin binding transcription activator 1 (Camta1) 0.93 0.040 -0.96 0.036 -0.01 0.997
coiled-coil domain containing 144B (Ccdc144b) 0.89 0.080 -1.05 0.044 -0.16 0.748
cytidine/uridine monophosphate kinase 2 (Cmpk2) 1.42 0.004 -1.53 0.002 -0.08 0.848
cytochrome C oxidase Subunit 7A1 (Cox7a1) 0.80 0.083 -0.89 0.057 -0.07 0.865
cathepsin K (Ctsk) 1.68 0.003 -1.06 0.038 0.64 0.239
c-x-c motif chemokine ligand 9 (Cxcl9) 1.50 0.036 -0.73 0.252 0.85 0.281
DExD/H-Box helicase 60 (Ddx60) 1.86 0.001 -1.09 0.026 0.81 0.116
DExD/H-Box helicase 58 (Dhx58) 1.49 0.008 -1.14 0.031 0.37 0.502
Eukaryotic translation initiation factor 2 alpha kinase 2 (Eif2ak2) 1.14 0.018 -0.92 0.049 0.24 0.590
family with sequence similarity 78 member A (Fam78a) 0.79 0.076 -1.03 0.025 -0.21 0.618
Fc fragment of IgG receptor Ia (Fcgr1) 2.32 0.032 -1.80 0.074 0.68 0.667
guanylate binding protein 3 (Gbp3) 1.66 0.001 -1.21 0.010 0.45 0.297
predicted gene 12250 (Gm12250) 1.87 0.006 -1.05 0.072 0.90 0.207
predicted gene 4951 (Gm4951) 1.81 0.013 -1.16 0.075 0.74 0.365
H2A clustered histone 6 (Hist1h2ao) 1.06 0.021 -0.73 0.096 0.33 0.432
integrin binding sialoprotein (Ibsp) 3.50 0.000 -1.46 0.009 2.19 0.008
interferon alpha inducible protein 27 (Ifi27l2a) 2.03 0.000 -1.75 0.000 0.26 0.525
interferon induced protein 44 (Ifi44) 2.63 0.000 -2.02 0.001 0.68 0.329
interferon induced protein 47 (Ifi47) 1.43 0.005 -0.83 0.072 0.62 0.187
interferon induced with helicase C domain 1 (Ifih1) 1.43 0.049 -1.31 0.069 0.16 0.848
interferon induced protein with tetratricopeptide repeats 1 (Ifit1) 2.70 0.000 -2.05 0.000 0.69 0.282
interferon induced protein with tetratricopeptide repeats 2 (Ifit2) 0.87 0.068 -1.01 0.038 -0.13 0.776
immunity related GTPase (Igtp) 1.46 0.004 -0.94 0.042 0.53 0.251
interferon regulatory factor 7 (Irf7) 2.42 0.000 -2.00 0.000 0.43 0.344
interferon regulatory factor 9 Irf9 0.83 0.069 -0.81 0.076 0.04 0.925
immunity related GTPase 1 (Irgm1) 1.41 0.008 -0.93 0.059 0.51 0.320
immunity related GTPase 2 (Irgm2) 1.22 0.014 -0.78 0.091 0.45 0.329
ISG15 ubiquitin like modifier (Isg15) 2.42 0.000 -1.89 0.003 0.61 0.401
inositol 1,4,5-trisphosphate receptor type 2 (Itpr2) 0.72 0.098 -0.82 0.064 -0.10 0.810
LEO1 Homolog (Leo1) 1.09 0.026 -1.08 0.028 0.03 0.946
galectin 3 binding protein (Lgals3bp) 1.63 0.001 -1.04 0.021 0.58 0.176
galectin 9 (Lgals9) 0.90 0.049 -0.78 0.083 0.15 0.727
ligand of numb-protein X 1 (Lnx1) 1.38 0.011 -0.85 0.087 0.55 0.300
LY6/PLAUR domain containing 2 (Lypd2) 6.64 0.000 -6.64 0.000 -0.03 0.950
MX dynamin like GTPase 2 (Mx2) 2.16 0.001 -1.85 0.002 0.35 0.575
out at first homolog (Oaf) 1.01 0.030 -0.93 0.043 0.10 0.808
2'-5'-oligoadenylate synthetase 2 (Oas2) 2.24 0.000 -2.00 0.000 0.25 0.641
2'-5'-oligoadenylate synthetase 1 (Oasl1) 1.65 0.014 -1.10 0.074 0.63 0.385
2'-5'-oligoadenylate synthetase 2 (Oasl2) 1.59 0.001 -1.23 0.009 0.37 0.387
poly (ADP-ribose) polymerase family member 14 (Parp14) 1.20 0.013 -0.92 0.044 0.30 0.501
poly(ADP-ribose) polymerase family member 9 (Parp9) 1.18 0.014 -0.92 0.045 0.28 0.526
placenta associated 8 (Plac8) 1.68 0.001 -1.11 0.016 0.57 0.184
RNA binding motif protein 22 (Rbm22) 0.91 0.046 -0.74 0.097 0.19 0.647
regulator of G protein Signaling 13 (Rgs13) 1.14 0.032 -1.85 0.002 -0.70 0.237
radical S-adenosyl methionine domain containing 2 (Rsad2) 2.20 0.000 -1.37 0.013 0.87 0.151
receptor transporter protein 4 (Rtp4) 2.36 0.000 -1.86 0.000 0.51 0.249
Schlafen Family Member 5 (Slfn5) 1.45 0.005 -1.09 0.024 0.38 0.421
Sarcalumenin (Srl) 4.24 0.007 -4.36 0.007 -0.12 0.803
tripartite motif containing 34A (Trim34a) 1.79 0.001 -1.51 0.004 0.29 0.567
ubiquitin specific peptidase 18 (Usp18) 2.23 0.000 -1.82 0.001 0.42 0.419
zinc finger protein 385B (Zfp385b) 0.86 0.054 -1.02 0.026 -0.15 0.711