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Table 1 The expression of premature ovarian failure is up-regulated, and the expression of differentially expressed genes is down-regulated after hUC-MSCs treatment

From: Effects of single and multiple transplantations of human umbilical cord mesenchymal stem cells on the recovery of ovarian function in the treatment of premature ovarian failure in mice

Name

POF/SHAM UP

MSCs/POF DOWN

MSCs/SHAM

Fold change values

P value

Fold change values

P value

Fold change values

P value

mmu-miR-101c

1.93

0.024

-2.11

0.040

-0.19

0.349

mmu-miR-1892

1.99

0.030

-1.36

0.049

0.64

0.057

mmu-miR-1894-3p

1.52

0.045

-1.03

0.020

0.49

0.141

mmu-miR-3070–2-3p

5.03

0.023

-5.62

0.018

-0.59

0.162

mmu-miR-3072-5p

2.97

0.020

-1.99

0.039

0.98

0.101

mmu-miR-3102-5p.2-5p

3.35

0.029

-2.39

0.032

0.96

0.119

mmu-miR-328-5p

1.56

0.042

-1.58

0.042

-0.01

0.904

mmu-miR-3547-5p

1.53

0.028

-1.05

0.049

0.48

0.138

mmu-miR-363-5p

2.56

0.044

-6.65

0.016

-4.09

0.023

mmu-miR-374b-5p

0.32

0.024

-0.60

0.007

-0.28

0.027

mmu-miR-374c-5p

0.40

0.042

-0.86

0.018

-0.46

0.016

mmu-miR-5122

1.05

0.033

-0.99

0.044

0.06

0.545

mmu-miR-652-5p

1.01

0.015

-0.99

0.020

0.03

0.610

mmu-miR-6965-5p

4.40

0.010

-2.80

0.017

1.60

0.021

mmu-miR-7088-5p

1.28

0.040

-0.61

0.033

0.67

0.076

mmu-miR-7235-5p

0.85

0.041

-0.66

0.042

0.19

0.192

mmu-miR-7648-5p

4.73

0.023

-2.80

0.041

1.94

0.079

mmu-miR-8110

1.51

0.017

-0.86

0.033

0.65

0.020

apoptosis-associated tyrosine kinase (Aatk)

1.10

0.022

-1.66

0.002

-0.55

0.248

apolipoprotein F (ApoF)

0.91

0.051

-2.27

0.002

-1.38

0.011

beta-1,3-N-acetylgalactosaminyltransferase 1 (B3galnt1)

0.73

0.099

-0.82

0.071

-0.04

0.914

apoptosis repeat containing 5 (Birc5)

0.74

0.090

-0.86

0.051

-0.13

0.740

calmodulin binding transcription activator 1 (Camta1)

0.93

0.040

-0.96

0.036

-0.01

0.997

coiled-coil domain containing 144B (Ccdc144b)

0.89

0.080

-1.05

0.044

-0.16

0.748

cytidine/uridine monophosphate kinase 2 (Cmpk2)

1.42

0.004

-1.53

0.002

-0.08

0.848

cytochrome C oxidase Subunit 7A1 (Cox7a1)

0.80

0.083

-0.89

0.057

-0.07

0.865

cathepsin K (Ctsk)

1.68

0.003

-1.06

0.038

0.64

0.239

c-x-c motif chemokine ligand 9 (Cxcl9)

1.50

0.036

-0.73

0.252

0.85

0.281

DExD/H-Box helicase 60 (Ddx60)

1.86

0.001

-1.09

0.026

0.81

0.116

DExD/H-Box helicase 58 (Dhx58)

1.49

0.008

-1.14

0.031

0.37

0.502

Eukaryotic translation initiation factor 2 alpha kinase 2 (Eif2ak2)

1.14

0.018

-0.92

0.049

0.24

0.590

family with sequence similarity 78 member A (Fam78a)

0.79

0.076

-1.03

0.025

-0.21

0.618

Fc fragment of IgG receptor Ia (Fcgr1)

2.32

0.032

-1.80

0.074

0.68

0.667

guanylate binding protein 3 (Gbp3)

1.66

0.001

-1.21

0.010

0.45

0.297

predicted gene 12250 (Gm12250)

1.87

0.006

-1.05

0.072

0.90

0.207

predicted gene 4951 (Gm4951)

1.81

0.013

-1.16

0.075

0.74

0.365

H2A clustered histone 6 (Hist1h2ao)

1.06

0.021

-0.73

0.096

0.33

0.432

integrin binding sialoprotein (Ibsp)

3.50

0.000

-1.46

0.009

2.19

0.008

interferon alpha inducible protein 27 (Ifi27l2a)

2.03

0.000

-1.75

0.000

0.26

0.525

interferon induced protein 44 (Ifi44)

2.63

0.000

-2.02

0.001

0.68

0.329

interferon induced protein 47 (Ifi47)

1.43

0.005

-0.83

0.072

0.62

0.187

interferon induced with helicase C domain 1 (Ifih1)

1.43

0.049

-1.31

0.069

0.16

0.848

interferon induced protein with tetratricopeptide repeats 1 (Ifit1)

2.70

0.000

-2.05

0.000

0.69

0.282

interferon induced protein with tetratricopeptide repeats 2 (Ifit2)

0.87

0.068

-1.01

0.038

-0.13

0.776

immunity related GTPase (Igtp)

1.46

0.004

-0.94

0.042

0.53

0.251

interferon regulatory factor 7 (Irf7)

2.42

0.000

-2.00

0.000

0.43

0.344

interferon regulatory factor 9 Irf9

0.83

0.069

-0.81

0.076

0.04

0.925

immunity related GTPase 1 (Irgm1)

1.41

0.008

-0.93

0.059

0.51

0.320

immunity related GTPase 2 (Irgm2)

1.22

0.014

-0.78

0.091

0.45

0.329

ISG15 ubiquitin like modifier (Isg15)

2.42

0.000

-1.89

0.003

0.61

0.401

inositol 1,4,5-trisphosphate receptor type 2 (Itpr2)

0.72

0.098

-0.82

0.064

-0.10

0.810

LEO1 Homolog (Leo1)

1.09

0.026

-1.08

0.028

0.03

0.946

galectin 3 binding protein (Lgals3bp)

1.63

0.001

-1.04

0.021

0.58

0.176

galectin 9 (Lgals9)

0.90

0.049

-0.78

0.083

0.15

0.727

ligand of numb-protein X 1 (Lnx1)

1.38

0.011

-0.85

0.087

0.55

0.300

LY6/PLAUR domain containing 2 (Lypd2)

6.64

0.000

-6.64

0.000

-0.03

0.950

MX dynamin like GTPase 2 (Mx2)

2.16

0.001

-1.85

0.002

0.35

0.575

out at first homolog (Oaf)

1.01

0.030

-0.93

0.043

0.10

0.808

2'-5'-oligoadenylate synthetase 2 (Oas2)

2.24

0.000

-2.00

0.000

0.25

0.641

2'-5'-oligoadenylate synthetase 1 (Oasl1)

1.65

0.014

-1.10

0.074

0.63

0.385

2'-5'-oligoadenylate synthetase 2 (Oasl2)

1.59

0.001

-1.23

0.009

0.37

0.387

poly (ADP-ribose) polymerase family member 14 (Parp14)

1.20

0.013

-0.92

0.044

0.30

0.501

poly(ADP-ribose) polymerase family member 9 (Parp9)

1.18

0.014

-0.92

0.045

0.28

0.526

placenta associated 8 (Plac8)

1.68

0.001

-1.11

0.016

0.57

0.184

RNA binding motif protein 22 (Rbm22)

0.91

0.046

-0.74

0.097

0.19

0.647

regulator of G protein Signaling 13 (Rgs13)

1.14

0.032

-1.85

0.002

-0.70

0.237

radical S-adenosyl methionine domain containing 2 (Rsad2)

2.20

0.000

-1.37

0.013

0.87

0.151

receptor transporter protein 4 (Rtp4)

2.36

0.000

-1.86

0.000

0.51

0.249

Schlafen Family Member 5 (Slfn5)

1.45

0.005

-1.09

0.024

0.38

0.421

Sarcalumenin (Srl)

4.24

0.007

-4.36

0.007

-0.12

0.803

tripartite motif containing 34A (Trim34a)

1.79

0.001

-1.51

0.004

0.29

0.567

ubiquitin specific peptidase 18 (Usp18)

2.23

0.000

-1.82

0.001

0.42

0.419

zinc finger protein 385B (Zfp385b)

0.86

0.054

-1.02

0.026

-0.15

0.711

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Journal of Ovarian Research

ISSN: 1757-2215

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