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Correction: H3K27ac-induced lncRNA PAXIP1-AS1 promotes cell proliferation, migration, EMT and apoptosis in ovarian cancer by targeting miR-6744-5p/PCBP2 axis
Journal of Ovarian Research volume 15, Article number: 108 (2022)
The Original Article was published on 09 June 2021
Correction: J Ovarian Res 14, 76 (2021)
Following publication of the original article [1], the authors identified an error in Figs. 1 and 5. The correct figures are shown in the following pages.
Expression pattern and functional role of PAXIP1-AS1 in OC cells. a RT-qPCR data of PAXIP1-AS1 expression in HOSEpiC cell line and OC cell lines. b Knockdown of PAXIP1-AS1 in SKOV3 and OVCAR3 cells validated by RT-qPCR. c-d Proliferation of SKOV3 and OVCAR3 cells upon PAXIP1-AS1 silencing was evaluated via colony formation assay and EdU assay. e Apoptosis of SKOV3 and OVCAR3 cells after PAXIP1-AS1 silencing was assessed through flow cytometry analysis. f Protein levels of Bax, Bcl-2, caspase-3 and caspase-9 under sh-PAXIP1-AS1 transfection were detected by western blot. g Migration of SKOV3 and OVCAR3 cells transfected with sh-PAXIP1-AS1 was confirmed by Transwell assay. h MMP2, MMP9, E-cadherin and N-cadherin protein levels were testified with western blot upon PAXIP1-AS1 knockdown. *p < 0.05
PCBP2 was a target of PAXIP1-AS1 in regulating OC cellular process. a Expression of PCBP2 in cells transfected with pcDNA3.1/PCBP2. b-c Cell proliferation with indicated transfection was tested by colony formation and EdU assays. d-e Apoptotic rate and levels of apoptosis-relevant proteins were respectively determined by flow cytometry analysis and western blot. f Cell migration in each group was measured through Transwell assay. g Levels of migration-related proteins and EMT-associated proteins in cells transfected with appointed plasmids were evaluated using western blot. *p < 0.05
Reference
Ma Y, Zheng W. H3K27ac-induced lncRNA PAXIP1-AS1 promotes cell proliferation, migration, EMT and apoptosis in ovarian cancer by targeting miR-6744-5p/PCBP2 axis. J Ovarian Res. 2021;14:76. https://doi.org/10.1186/s13048-021-00822-z.
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Ma, Y., Zheng, W. Correction: H3K27ac-induced lncRNA PAXIP1-AS1 promotes cell proliferation, migration, EMT and apoptosis in ovarian cancer by targeting miR-6744-5p/PCBP2 axis. J Ovarian Res 15, 108 (2022). https://doi.org/10.1186/s13048-022-01038-5
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DOI: https://doi.org/10.1186/s13048-022-01038-5