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  1. The oocyte and its surrounding cumulus cells (CCs) exist as an inseparable entity. The maturation of the oocyte relies on communication between the oocyte and the surrounding CCs. However, oocyte evaluation is...

    Authors: Yena Hu, Ran Zhang, Shuoping Zhang, Yaxing Ji, Qinwei Zhou, Lizhi Leng, Fei Meng, Fei Gong, Guangxiu Lu, Ge Lin and Liang Hu
    Citation: Journal of Ovarian Research 2023 16:225
  2. High-grade serous ovarian cancer (OvCa) is the most common type of epithelial OvCa. It is usually diagnosed in advanced stages, leaving a woman’s chance of survival below 50%. Despite traditional chemotherapeu...

    Authors: Melayshia McFadden, Santosh Kumar Singh, Briana Kinnel, Sooryanarayana Varambally and Rajesh Singh
    Citation: Journal of Ovarian Research 2023 16:220
  3. Angiogenesis and metastasis contributes substantially to the poor outcome of patients with ovarian cancer. We aimed to explore the role and mechanisms of the long non-coding RNA NEAT1 (nuclear enriched abundan...

    Authors: Yang Liu, Yan Li, Yanzhi Wu, Yiyue Zhao, Xi Hu and Chunyi Sun
    Citation: Journal of Ovarian Research 2023 16:219
  4. High-grade serous carcinoma (HGSC) is the most common and aggressive subtype of epithelial ovarian cancer, characterized by gain-of-function TP53 mutations originating in the fallopian tube epithelium. Therapeuti...

    Authors: Madison Pereira, Alice Glogova, Jacob Haagsma, Julia Stewart, Trevor G. Shepherd and Jim Petrik
    Citation: Journal of Ovarian Research 2023 16:218
  5. Authors: Xing‑Hua Pan, Xue‑Juan Zhang, Xiang Yao, Ni‑Ni Tian, Zai‑Ling Yang, Kai Wang, Xiang‑Qing Zhu, Jing Zhao, Jie He, Xue‑Min Cai, Rong‑Qing Pang and Guang‑Ping Ruan
    Citation: Journal of Ovarian Research 2023 16:217

    The original article was published in Journal of Ovarian Research 2021 14:133

  6. Women with polycystic ovary syndrome (PCOS) have higher intestinal mucosal permeability, leading to the lipopolysaccharide (LPS) leakage and endotoxemia. This, in turn, leads to oxidative stress (OS) and neuro...

    Authors: Negin Nikrad, Mahdieh Abbasalizad Farhangi, Fatemeh Pourteymour Fard Tabrizi, Maryam Vaezi, Ata Mahmoudpour and Mehran Mesgari-Abbasi
    Citation: Journal of Ovarian Research 2023 16:216
  7. Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts, high androgen levels, and irregular menstruation. The causality between PCOS and breast cancer (BC) has been widely dis...

    Authors: Runxiang Cao, Lanlan Chen, Yutong Liu, Xuyutian Wang, Ruolin Ma, Qian Zhao and Ye Du
    Citation: Journal of Ovarian Research 2023 16:215
  8. No residual disease (CC 0) following cytoreductive surgery is pivotal for the prognosis of women with advanced stage epithelial ovarian cancer (EOC). Improving CC 0 resection rates without increasing morbidity...

    Authors: Diederick de Jong, Amudha Thangavelu, Timothy Broadhead, Inga Chen, Dermot Burke, Richard Hutson, Racheal Johnson, Angelika Kaufmann, Peter Lodge, David Nugent, Aaron Quyn, Georgios Theophilou and Alexandros Laios
    Citation: Journal of Ovarian Research 2023 16:214
  9. The oocyte cumulus complex is mainly composed of an oocyte, the perivitelline space, zona pellucida and numerous granulosa cells. The cumulus granulosa cells (cGCs) provide a particularly important microenviro...

    Authors: Chongyi Shu, Yiqi Yu, Xiaopan Chen, Jiansheng Guo, Yier Zhou, Dandan Wu, Tianyun Yang, Yuhang Fan, Qiongxiao Huang and Jing Shu
    Citation: Journal of Ovarian Research 2023 16:213
  10. To study whether CAG repeat polymorphism of androgen receptor (AR) contributes to the risk of polycystic ovarian morphology (PCOM) with antral follicle count (AFC) ≥ 20 in the context of new international guideli...

    Authors: Xueqi Yan, Xueying Gao, Qian Shang, Ziyi Yang, Yuteng Wang, Li Liu, Wei Liu, Dan Liu, Fang Cheng, Shigang Zhao, Han Zhao, Junli Zhao and Zi-Jiang Chen
    Citation: Journal of Ovarian Research 2023 16:211
  11. Premature ovarian insufficiency (POI) is a highly heterogeneous disease, and up to 25% of the cases can be explained by genetic causes. G protein-coupled receptor 3 (GPR3) plays an important role in oocyte arr...

    Authors: Shuting Ren, Feng Zhang, Lingyue Shang, Xi Yang, Yuncheng Pan, Xiaojin Zhang and Yanhua Wu
    Citation: Journal of Ovarian Research 2023 16:210
  12. The therapeutic effect of poly (ADP-ribose) polymerase inhibitors (PARPi) monotherapy compared with platinum-based chemotherapy, and the impact to subsequent platinum-based chemotherapy after PARPi resistance ...

    Authors: Yana Ma, Jiale Liu, Ning Li, Hualei Bu, Yongwen Huang, Chengjuan Jin, Hao Wen, Shuai Feng, Hui Zhang, Xiaorong Yang, Beihua Kong, Lingying Wu and Kun Song
    Citation: Journal of Ovarian Research 2023 16:209
  13. Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Animal models have been developed and used as tools to unrave...

    Authors: Haowen Wu, Bining Zhao, Qiyang Yao and Jihong Kang
    Citation: Journal of Ovarian Research 2023 16:207
  14. Follicular microenvironment has been proposed as an important factor for oocyte grown and maturation. We sought to evaluate the oxidative stress and inflammatory levels in follicular fluid (FF) and association...

    Authors: Yan Huang, Yi Cheng, Min Zhang, Yan Xia, Xiaoyan Chen, Yexing Xian, Dewei Lin, Suyan Xie and Xinyu Guo
    Citation: Journal of Ovarian Research 2023 16:206
  15. The immune system played a multifaceted role in ovarian cancer (OC) and was a significant mediator of ovarian carcinogenesis. Various immune cells and immune gene products played an integrated role in ovarian ...

    Authors: Hongjun Fei, Xu Han, Yanlin Wang and Shuyuan Li
    Citation: Journal of Ovarian Research 2023 16:205
  16. Studies have shown that supplementation with recombinant human GH (rh-GH) during ovarian stimulation (OS) may improve the ovarian response and clinical outcomes of IVF. However, it remains unclear whether GH i...

    Authors: Yilun Sui, Min Xiao, Jing Fu, Lu Li, Yining Xu, Caixia Lei and Xiaoxi Sun
    Citation: Journal of Ovarian Research 2023 16:204
  17. Premature ovarian insufficiency (POI) is an important cause of infertility characterized by the functional decline of the ovary. Granulosa cells (GCs) around oocytes are critical for folliculogenesis, and GC d...

    Authors: Dan Liu, Xiaohong Guan, Wenqiang Liu, Yanping Jia, Hong Zhou, Chenxiang Xi, Mei Zhao, Yuan Fang, Li Wu and Kunming Li
    Citation: Journal of Ovarian Research 2023 16:203
  18. Gynecologic cancers comprise malignancies in the female reproductive organs. Ovarian cancer ranks sixth in terms of incidence rates while seventh in terms of mortality rates. The stage at which ovarian cancer ...

    Authors: Khushbukhat Khan, Sameen Zafar, Yasmin Badshah, Naeem Mahmood Ashraf, Mehak Rafiq, Lubna Danish, Maria Shabbir, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal and Suhail Razak
    Citation: Journal of Ovarian Research 2023 16:202
  19. The factors affecting the cumulative live birth rate (CLBR) of PCOS (Polycystic ovary syndrom) patients who received in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) needs ...

    Authors: You Li, Leizhen Xia, Zengming Li, Ziyu Zhang and Ru Jiang
    Citation: Journal of Ovarian Research 2023 16:201
  20. Patients with epithelial ovarian carcinoma (EOC) are usually diagnosed at an advanced stage with tumour cell invasion. However, identifying the underlying molecular mechanisms and biomarkers of EOC proliferati...

    Authors: Yuanfu Zhang, Shu Sun, Yue Qi, Yifan Dai, Yangyang Hao, Mengyu Xin, Rongji Xu, Hongyan Chen, Xiaoting Wu, Qian Liu, Congcong Kong, Guangmei Zhang, Peng Wang and Qiuyan Guo
    Citation: Journal of Ovarian Research 2023 16:200
  21. Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life. Previous studies have demonstrated that ...

    Authors: Wenjie Dai, Hong Yang, Bo Xu, Tiantian He, Ling Liu, Xiaoqian Ma, Jiaxue Ma, Guoqin Yang, Rui Si, Xiuying Pei, Xing Du and Xufeng Fu
    Citation: Journal of Ovarian Research 2023 16:198
  22. Whether pretreatment with gonadotropin-releasing hormone agonist (GnRHa) can improve the pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles is controversial. The inconsistencies in the results of...

    Authors: Bin Xu, Zhaojuan Hou, Nenghui Liu, Jing Zhao and Yanping Li
    Citation: Journal of Ovarian Research 2023 16:197
  23. Ovarian cancer (OV) is the most fatal gynecological malignant tumor worldwide, with high recurrence rates and great heterogeneity. Pyroptosis is a newly-acknowledged inflammatory form of cell death with an ess...

    Authors: Jiani Yang, Chao Wang, Yue Zhang, Shanshan Cheng, Yanna Xu and Yu Wang
    Citation: Journal of Ovarian Research 2023 16:196
  24. Natural cycle- in vitro fertilization (NC-IVF) is particularly recommended for women with decreased ovarian reserve (DOR) or poor response to controlled ovarian hyperstimulation. In these cases, it can be chal...

    Authors: Tian Tian, Yu Li, Jiaxin Lv, Lixue Chen, Yuanyuan Wang, Rui Yang, Ping Liu, Rong Li and Jie Qiao
    Citation: Journal of Ovarian Research 2023 16:195
  25. The nuclear receptor subfamily 5 group A member 1 (NR5A1), encoding steroidogenic factor 1 (SF-1), has been identified as a critical factor in gonadal development in animal studies. A previous study of ours sugge...

    Authors: Laura Danti, Karolina Lundin, Kirsi Sepponen, Dawit A. Yohannes, Juha Kere, Timo Tuuri and Juha S. Tapanainen
    Citation: Journal of Ovarian Research 2023 16:194
  26. Evaluating the efficacy of letrozole overlapped with gonadotropin-modified letrozole protocol (mLP) for diminished ovarian reserve (DOR) or advanced-age women with repeated cycles.

    Authors: Xiaojia Li, Jingbo Chen, Yang Zhao, Fengyi He, Meijun Zeng, Guijun Guan and Xiaomiao Zhao
    Citation: Journal of Ovarian Research 2023 16:193
  27. The failure of frozen-thawed blastocysts to re-expand adequately within a few hours after warming has been reported to have a negative impact on assisted reproductive technology (ART) outcomes. However, the ex...

    Authors: Ayumu Ito, Yukiko Katagiri, Satoko Oigawa, Kenji Amano, Koichiro Ichizawa, Yukiko Tokuda, Mami Unagami, Masato Yoneyama, Takahiro Tsuchiya, Mami Sekiguchi, Mayuko Furui, Kentaro Nakaoka, Nahomi Umemura, Yuko Hayashi, Yuko Tamaki, Koichi Nagao…
    Citation: Journal of Ovarian Research 2023 16:192

    The Correction to this article has been published in Journal of Ovarian Research 2024 17:109

  28. Recent studies have suggested a potential link between systemic inflammatory regulators and primary ovarian insufficiency (POI); however, a causal relationship between them remains unclear. In this study, we e...

    Authors: Jiahui Wang, Xia Zhao, Rong Luo, Di Xia, Yi Liu, Tao Shen and Yuanjiao Liang
    Citation: Journal of Ovarian Research 2023 16:191
  29. Because often introduced without proper validation studies, so-called “add-ons” to IVF have adversely affected in vitro fertilization (IVF) outcomes worldwide. All-freeze cycles (embryo banking, EB) with subse...

    Authors: Norbert Gleicher, Sarah K. Darmon, Pasquale Patrizio and David. H. Barad
    Citation: Journal of Ovarian Research 2023 16:190
  30. The concentration of human chorionic gonadotropin (hCG)/ luteinizing hormone (LH) after triggering is generally accepted as a predictor of the normal ovarian response to the trigger, but few studies have explo...

    Authors: Hao Jin, Haiyan Yang, Jiujia Zheng, Jiechun Zhou and Rong Yu
    Citation: Journal of Ovarian Research 2023 16:189
  31. Cancer cells may develop resistance to cisplatin by various mechanisms. Yet, the exact mechanism of cisplatin in ovarian cancer remains unclear. Recent studies have shown that 3’-phospoadenosine 5’-phosphosulf...

    Authors: Lei Sun, Wei-Xue Ji, Yan Li, Ze-Lian Li, Can-Can Duan, Bai-rong Xia and Lan Xiao
    Citation: Journal of Ovarian Research 2023 16:187
  32. Tumor-associated lncRNAs regulated by epigenetic modification switches mediate immune escape and chemoresistance in ovarian cancer (OC). However, the underlying mechanisms and concrete targets have not been sy...

    Authors: Lu Chen, Wujiang Gao, Li Lin, Chunli Sha, Taoqiong Li, Qi Chen, Hong Wei, Meiling Yang, Jie Xing, Mengxue Zhang, Shijie Zhao, Wenlin Xu, Yuefeng Li, Lulu Long and Xiaolan Zhu
    Citation: Journal of Ovarian Research 2023 16:186
  33. Opa interacting protein 5 (OIP5), which is a cancer/testis-specific gene, plays a cancer-promoting role in various types of human cancer. However, the role of OIP5 in the carcinogenesis and progression of ovar...

    Authors: Xin Zhang, Wenjie Gu, Aiqin Lin, Renjie Duan, Likai Lian, Yuanyuan Huang, Tiechen Li and Qing Sun
    Citation: Journal of Ovarian Research 2023 16:185
  34. We aimed to determine whether adding metformin to carboplatin treatment would reduce the damage to ovarian reserve associated with carboplatin use.

    Authors: Sevgi Ayhan, Necati Hancerliogullari, Gurhan Guney, Murat Gozukucuk, Muzaffer Caydere, Sergul Selvi Guney, Aytekin Tokmak and Yusuf Ustun
    Citation: Journal of Ovarian Research 2023 16:184
  35. Two polymorphisms, rs6165 and rs6166 located in the intracellular domain of FSHR has been reported to affect folliculogenesis, steroidogenesis and oocyte maturation. Several studies have highlighted the role of F...

    Authors: Mandeep Kaur, Sukhjashanpreet Singh and Anupam Kaur
    Citation: Journal of Ovarian Research 2023 16:183
  36. Most women with anovulatory infertility show polycystic ovarian syndrome (PCOS), and androgen excess is known as a key factor involved in pathogenicity of PCOS. However, the mechanism of follicular development...

    Authors: Yoko Urata, Reza Salehi, Brandon A. Wyse, Sahar Jahangiri, Clifford L. Librach, Chii-Ruey Tzeng, Yutaka Osuga and Benjamin Tsang
    Citation: Journal of Ovarian Research 2023 16:182
  37. MUC16 (CA125) is a commonly used tumor marker for ovarian cancer screening and reported to be an immunosuppressive factor by acting on the sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on the sur...

    Authors: Yuliang Wu, Qi Liu, Yan Xie, Jihui Zhu, Sai Zhang, Yao Ge, Jing Guo, Ning Luo, Wei Huang, Runping Xu, Shupeng Liu and Zhongping Cheng
    Citation: Journal of Ovarian Research 2023 16:181
  38. C-X-C motif chemokine ligand 9 (CXCL9), which is involved in the pathological processes of various human cancers, has become a hot topic in recent years. We developed a radiomic model to identify CXCL9 status ...

    Authors: Rui Gu, Siyi Tan, Yuping Xu, Donghui Pan, Ce Wang, Min Zhao, Jiajun Wang, Liwei Wu, Shaojie Zhao, Feng Wang and Min Yang
    Citation: Journal of Ovarian Research 2023 16:180
  39. Mature and immature teratomas are differentiated based on tumor markers and calcification or fat distribution. However, no study has objectively quantified the differences in calcification and fat distribution...

    Authors: Akari Nakamori, Hideaki Tsuyoshi, Tetsuya Tsujikawa, Makoto Orisaka, Tetsuji Kurokawa and Yoshio Yoshida
    Citation: Journal of Ovarian Research 2023 16:179
  40. Oocyte maturation arrest results in female infertility and the genetic etiology of this phenotype remains largely unknown. Previous studies have proven that cyclins play a significant role in the cell cycle bo...

    Authors: Congjing Wang, Meng Xi Chen, Yuan Zhang, Xue Bai, Qiqi Cao, Jian Han, Nana Zhang, Chun Zhao, Xiufeng Ling, Ximan Rui, Yichun Guan, Junqiang Zhang and Ran Huo
    Citation: Journal of Ovarian Research 2023 16:178
  41. Ovarian cancer (OC) is the most malignant tumor with the worst prognosis in female reproductive system. Mitophagy and long non-coding RNAs (lncRNAs) play pivotal roles in tumorigenesis, development, and drug r...

    Authors: Jiao Wang, Xiaocui Zhang, Fei Zheng, Qing Yang and Fangfang Bi
    Citation: Journal of Ovarian Research 2023 16:177
  42. Traditional Chinese medicine has been used for a long time to treat a variety of gynecological diseases. Among various traditional Chinese medicine, Dingkun Pill (DK) has been used for the treatment of female ...

    Authors: Mengqing Gu, Han Cai, Weinan Deng, Yedong Tang, Shuailin Du, Peiran Wang, Wenbo Deng, Haibin Wang, Aijun Sun and Shuangbo Kong
    Citation: Journal of Ovarian Research 2023 16:176
  43. Follicular development in mammalian ovaries is a complex and dynamic process, and the interactions and regulatory-feedback loop between the follicular microenvironment, granulosa cells (GCs), and oocytes can a...

    Authors: Ziwen Xu, Tongwei Zhang, Jingyi Hu, Junya Zhang, Guang Yang, Jiahuan He, Huihui Wang, Ran Jiang and Guidong Yao
    Citation: Journal of Ovarian Research 2023 16:175
  44. Some major challenges of ovarian tissue vitrification and transplantation include follicle apoptosis induced by cryopreservation and ischemia-reperfusion injury, as well as ovarian follicle loss during post-tr...

    Authors: Fei Wang, Yuan Tian, Liwen Huang, Tian Qin, Wenye Ma, Chengbin Pei, Bo Xu, Hang Han, Xinrui Liu, Pengge Pan, Xiaoli Yu, Qin Chang, Yanrong Wang, Shuya Zhang and Xiuying Pei
    Citation: Journal of Ovarian Research 2023 16:173
  45. Explore the therapeutic role of human umbilical mesenchymal stem cells (hUMSCs) transplantation for regeneration of ECM components and restoration of follicular development in mice.

    Authors: Yin Shuyuan, Wang Meimei, Li Fenghua, Zhao Huishan, Chu Min, Bao Hongchu and Liu Xuemei
    Citation: Journal of Ovarian Research 2023 16:172

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