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  1. Content type: Research

    In human IVF, embryos cultured with a lower O2 tension (5%) can give rise to higher success rates when compared with normoxic conditions (20%). However, the mechanisms behind the beneficial effects of reduced oxy...

    Authors: Yun-Yi Ma, Huei-Wen Chen and Chii-Ruey Tzeng

    Citation: Journal of Ovarian Research 2017 10:47

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  2. Content type: Research

    To explore the risk factors of endometriosis-associated ovarian cancer (EAOC) in women with ovarian endometriosis (OEM) aged 45 years and above in China.

    Authors: Zheng-Xing He, Hong-Hui Shi, Qing-Bo Fan, Lan Zhu, Jin-Hua Leng, Da-Wei Sun, Zhan-Fei Li, Keng Shen, Shu Wang and Jing-He Lang

    Citation: Journal of Ovarian Research 2017 10:45

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  3. Content type: Review

    As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cell...

    Authors: Cláudia Freitas, Ana Catarina Neto, Liliana Matos, Elisabete Silva, Ângela Ribeiro, João Luís Silva-Carvalho and Henrique Almeida

    Citation: Journal of Ovarian Research 2017 10:44

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  4. Content type: Review

    Endometriosis is an estrogen-dependent chronic inflammatory condition that affects women in their reproductive period causing infertility and pelvic pain. The disease, especially at the ovarian site has been s...

    Authors: Ana Maria Sanchez, Valeria Stella Vanni, Ludovica Bartiromo, Enrico Papaleo, Eran Zilberberg, Massimo Candiani, Raoul Orvieto and Paola Viganò

    Citation: Journal of Ovarian Research 2017 10:43

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  5. Content type: Research

    Oocyte quality is a key limiting factor in female fertility which is primarily reflected in morphological features. Centrally located cytoplasm granulation (CLCG) is one type of cytoplasmic dimorphism exhibite...

    Authors: Philippe Merviel, Rosalie Cabry, Karen Chardon, Elodie Haraux, Florence Scheffler, Naima-belhadri Mansouri, Aviva Devaux, Hikmat Chahine, Véronique Bach, Henri Copin and Moncef Benkhalifa

    Citation: Journal of Ovarian Research 2017 10:42

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  6. Content type: Research

    Ovarian hyperstimulation syndrome (OHSS) is a disorder associated with elevated serum VEGFA following chorionic gonadotropin (hCG) exposure in controlled ovarian stimulation (COS) cycles in women. In this stud...

    Authors: C. V. Bishop, D. M. Lee, O. D. Slayden and X. Li

    Citation: Journal of Ovarian Research 2017 10:41

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  7. Content type: Research

    MMP-7 and TIMP-1 may play a role in the pathogenesis of cancer disease. In this study we investigated plasma levels of selected metalloproteinase and its tissue inhibitor in comparison to plasma levels of the ...

    Authors: Grażyna Ewa Będkowska, Ewa Gacuta, Monika Zajkowska, Edyta Katarzyna Głażewska, Joanna Osada, Maciej Szmitkowski, Lech Chrostek, Milena Dąbrowska and Sławomir Ławicki

    Citation: Journal of Ovarian Research 2017 10:39

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  8. Content type: Research

    Ovarian tissue cryopreservation is a technique for fertility preservation addressed to prepubertal girls or to patients for whom no ovarian stimulation is possible before initiation of gonadotoxic treatments. ...

    Authors: Tristan Zver, Elodie Mouloungui, Aurélie Berdin, Christophe Roux and Clotilde Amiot

    Citation: Journal of Ovarian Research 2017 10:38

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  9. Content type: Research

    Oocyte maturation and preimplantation embryo development are controlled by array of genes that are post-transcriptionally regulated by microRNAs. With respect to this, previously, we identified altered express...

    Authors: Pritam Bala Sinha, Dawit Tesfaye, Franca Rings, Munir Hossien, Michael Hoelker, Eva Held, Christaine Neuhoff, Ernst Tholen, Karl Schellander and Dessie Salilew-Wondim

    Citation: Journal of Ovarian Research 2017 10:37

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  10. Content type: Research

    The survival duration of elderly patients with epithelial ovarian carcinoma is shorter than that of their younger counterparts. This variation in survival duration is likely attributed to differences in the di...

    Authors: Fei Deng, Xia Xu, Mengmeng Lv, Binhui Ren, Yan Wang, Wenwen Guo, Jifeng Feng and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2017 10:36

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  11. Content type: Research

    We aimed to test the hypothesis that the correlation of the changes in the blood Androstenedione (A4) levels to the number of selected follicles during ovulation induction with low-dose recombinant human follicle...

    Authors: Eser Sefik Ozyurek, Tevfik Yoldemir and Gokhan Artar

    Citation: Journal of Ovarian Research 2017 10:34

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  12. Content type: Research

    Ovarian cancer is the leading lethal, gynecological malignancy in the United States. No doubt, the continued morbidity and mortality of ovarian cancer reflects a poor understanding of invasive mechanisms. Rece...

    Authors: Jun Wei, Lahong Zhang, Jennifer Li, Shuguang Zhu, Minghui Tai, Clifford W. Mason, Julia A. Chapman, Evelyn A. Reynolds, Carl P Weiner and Helen H Zhou

    Citation: Journal of Ovarian Research 2017 10:33

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  13. Content type: Research

    Diminished ovarian reserve(DOR) is associated with female infertility and poor response to ovarian stimulation. Our objective was to assess the effect of dehydroepiandrosterone(DHEA) on DOR women and to explor...

    Authors: Qiaofei Hu, Liming Hong, Mingyue Nie, Qin Wang, Ying Fang, Yinmei Dai, Yanhong Zhai, Shuyu Wang, Chenghong Yin and Xiaokui Yang

    Citation: Journal of Ovarian Research 2017 10:32

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  14. Content type: Research

    Ovarian cancer is the leading cause of death for gynecological cancers and the 6th cause of women cancer death in developed countries. The late stage detection, the peritoneal dissemination and the acquisition...

    Authors: Benoît Thibault and Bertrand Jean-Claude

    Citation: Journal of Ovarian Research 2017 10:31

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  15. Content type: Research

    Accumulated evidence has demonstrated that Mammalian hepatitis B X-interacting protein (HBXIP) has broad roles in cancer. Although HBXIP is associated with a variety of cancers, the HBXIP protein expression le...

    Authors: Yixuan Wang, Jie Sun, Nan Li, Shuanlong Che, Tiefeng Jin, Shuangping Liu and Zhenhua Lin

    Citation: Journal of Ovarian Research 2017 10:26

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  16. Content type: Research

    Resistance to platinum-based chemotherapy remains a great challenge for ovarian cancer treatment. The human let-7 family contains 13 members located on nine different chromosomes, and most members have been im...

    Authors: Man Xiao, Jing Cai, Liqiong Cai, Jinghui Jia, Lisha Xie, Ying Zhu, Bangxing Huang, Dongdong Jin and Zehua Wang

    Citation: Journal of Ovarian Research 2017 10:24

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  17. Content type: Case report

    Although immune system plays a key role in the pathogenesis of both endometriosis and ovarian cancer, its function is different. Therefore, we hypothesized, that selected immune parameters can serve as diagnos...

    Authors: Olimpia Sipak-Szmigiel, Piotr Włodarski, Elżbieta Ronin-Walknowska, Andrzej Niedzielski, Beata Karakiewicz, Sylwia Słuczanowska-Głąbowska, Maria Laszczyńska and Witold Malinowski

    Citation: Journal of Ovarian Research 2017 10:25

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  18. Content type: Research

    The lack of consensus around best practices for management of borderline ovarian tumors (BOT) is, in part, to the lack of available data and of clarity in interpreting relationships among various factors that ...

    Authors: Xi Chen, Chenyan Fang, Tao Zhu, Ping Zhang, Aijun Yu and Shihua Wang

    Citation: Journal of Ovarian Research 2017 10:23

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  19. Content type: Brief Communication

    Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecu...

    Authors: Wen-Chung Wang, Ya-Ting Lee and Yen-Chein Lai

    Citation: Journal of Ovarian Research 2017 10:22

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  20. Content type: Research

    Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening.

    Authors: Renée T. Fortner, Allison F. Vitonis, Helena Schock, Anika Hüsing, Theron Johnson, Raina N. Fichorova, Titilayo Fashemi, Hidemi S. Yamamoto, Anne Tjønneland, Louise Hansen, Kim Overvad, Marie-Christine Boutron-Ruault, Marina Kvaskoff, Gianluca Severi, Heiner Boeing, Antonia Trichopoulou…

    Citation: Journal of Ovarian Research 2017 10:20

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  21. Content type: Research

    There is substantial evidence both in humans and in animals that a prolonged reduction in plasma thyroid hormone concentration leads to reproductive problems, including disturbed folliculogenesis, impaired ovu...

    Authors: Li Meng, Eddy Rijntjes, Hans J. M. Swarts, Jaap Keijer and Katja J. Teerds

    Citation: Journal of Ovarian Research 2017 10:19

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  22. Content type: Research

    In this work, a detailed anatomical description of the ovarian plexus nerve (OPN) in rats is presented. The distribution of the OPN was analyzed by gross anatomy; the features of the superior mesenteric gangli...

    Authors: César F. Pastelín, Nora H. Rosas, Leticia Morales-Ledesma, Rosa Linares, Roberto Domínguez and Carolina Morán

    Citation: Journal of Ovarian Research 2017 10:18

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  23. Content type: Case report

    Cytochrome P450 oxidoreductase deficiency (PORD) is a rare disease exhibiting a variety of clinical manifestations. It can be difficult to differentiate with other diseases such as 21-hydroxylase deficiency (2...

    Authors: Yang Bai, Jinhui Li and Xiaoli Wang

    Citation: Journal of Ovarian Research 2017 10:16

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  24. Content type: Research

    Preoperative evaluation of ovarian tumors is challenging. This study was undertaken to evaluate the performance of conventional two-dimensional (2D) ultrasound and CA125 in predicting malignant or benign natur...

    Authors: Riikka Johanna Niemi, Sami Kristian Saarelainen, Tiina Hannele Luukkaala and Johanna Unelma Mäenpää

    Citation: Journal of Ovarian Research 2017 10:15

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  25. Content type: Case report

    Mature cystic teratomas are usually found in the ovaries. They are bilateral in 10 to 15% of cases and multiple cystic teratomas may be present in one ovary. The aim of this study is to clarify if development ...

    Authors: Wen-Chung Wang and Yen-Chein Lai

    Citation: Journal of Ovarian Research 2017 10:17

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  26. Content type: Review

    In adults, the ovary is characterized with extensive angiogenesis and regular intervals of rapid growth. Ovarian function is dependent on the network of angiogenic vessels which enable the follicle and/or corp...

    Authors: Qi Xie, Zuowang Cheng, Xiaocui Chen, Corrinne G. Lobe and Ju Liu

    Citation: Journal of Ovarian Research 2017 10:13

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  27. Content type: Research

    The detection of CA125 has been used in the follow up of ovarian cancer. At present, some scholars believe that serum CA125 has no clinical value for the follow-up monitoring the recurrence for postoperative p...

    Authors: Na Guo and Zhilan Peng

    Citation: Journal of Ovarian Research 2017 10:14

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  28. Content type: Research

    The purpose of this study was to examine proliferative and apoptotic activity in relation with BRCA1 expression in ovarian epithelial inclusions (OEIs), the putative precursor lesions of ovarian epithelial can...

    Authors: Yiying Wang, Yue Wang, Li Wei, Shuhui Hong, Miaoqing Zhao, Xi Zhang and Wenxin Zheng

    Citation: Journal of Ovarian Research 2017 10:12

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  29. Content type: Research

    The mechanism of aggressive character of ovarian cancer and unsuccessful treatment of women with this deadly disease has been recently explained by the theory of cancer stem cells (CSCs). It has been reported ...

    Authors: Natasa Kenda Suster, Spela Smrkolj and Irma Virant-Klun

    Citation: Journal of Ovarian Research 2017 10:11

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  30. Content type: Research

    MicroRNAs (miRNAs) regulate the expression of genes involved in various cellular functions related to metabolism, inflammation, and reproduction. This study evaluated the effects of sex hormones and obesity on...

    Authors: Weixi Xiong, Ying Lin, Lili Xu, Amin Tamadon, Shien Zou, Fubo Tian, Ruijin Shao, Xin Li and Yi Feng

    Citation: Journal of Ovarian Research 2017 10:10

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  31. Content type: Research

    It has long been appreciated that different subtypes (serous, clear cell, endometrioid and mucinous) of epithelial ovarian carcinoma (EOC) have distinct pathogenetic pathways. However, clinical management, esp...

    Authors: Mengjiao Li, Haoran Li, Fei Liu, Rui Bi, Xiaoyu Tu, Lihua Chen, Shuang Ye and Xi Cheng

    Citation: Journal of Ovarian Research 2017 10:9

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  32. Content type: Research

    Glycosphingolipids are important compounds of the plasma membrane of mammalian cells and a number of them have been associated with malignant transformation and progression, reinforcing tumour aggressiveness a...

    Authors: Tatiana Pochechueva, Shahidul Alam, Andreas Schötzau, Alexander Chinarev, Nicolai V. Bovin, Neville F. Hacker, Francis Jacob and Viola Heinzelmann-Schwarz

    Citation: Journal of Ovarian Research 2017 10:8

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  33. Content type: Research

    The aim of our study was to investigate the clinical features and expression levels of hypothalamic-pituitary-gonadal axis-related hormone receptors in low-grade serous ovarian cancer (LGSC).

    Authors: Zheng Feng, Hao Wen, Xingzhu Ju, Rui Bi, Xiaojun Chen, Wentao Yang and Xiaohua Wu

    Citation: Journal of Ovarian Research 2017 10:7

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  34. Content type: Research

    Our objective was to explore the impact of a single dose of an aromatase inhibitor (letrozole) administered at defined times of the follicular phase or immediately after ovulation on dominant follicle developm...

    Authors: H.C.M. Allaway, D.R. Chizen, G.P. Adams and R.A. Pierson

    Citation: Journal of Ovarian Research 2017 10:6

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  35. Content type: Research

    Ovarian transplantation is a useful method for preserving the fertility of young women with cancer who undergo radiotherapy and chemotherapy. Follicle-stimulating hormone (FSH) is use to protect transplanted o...

    Authors: Wen-Zhi Ma, Xiao-Min Zheng, Chang-Chun Hei, Cheng-Jun Zhao, Sha-Sha Xie, Qing Chang, Yu-Fang Cai, Hua Jia, Xiu-Ying Pei and Yan-Rong Wang

    Citation: Journal of Ovarian Research 2017 10:5

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  36. Content type: Research

    A standard histomorphometric approach has been used for nearly 40 years that identifies atretic (e.g., dying) follicles by counting the number of pyknotic granulosa cells (GC) in the largest follicle cross-sec...

    Authors: Bahar Uslu, Carola Conca Dioguardi, Monique Haynes, De-Qiang Miao, Meltem Kurus, Gloria Hoffman and Joshua Johnson

    Citation: Journal of Ovarian Research 2017 10:3

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  37. Content type: Research

    IVF cycles which result in only one good quality embryo, and a second poor quality embryo present a dilemma when the decision involves transferring two embryos. The aim of this study was to evaluate whether a ...

    Authors: Eliana Muskin Wintner, Anat Hershko-Klement, Keren Tzadikevitch, Yehudith Ghetler, Ofer Gonen, Oren Wintner, Adrian Shulman and Amir Wiser

    Citation: Journal of Ovarian Research 2017 10:2

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  38. Content type: Research

    Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women of reproductive age. The study was commenced to assess the favorable effects of Rutin against metabolic, biochemical, histological...

    Authors: Sarwat Jahan, Faryal Munir, Suhail Razak, Anam Mehboob, Qurat Ul Ain, Hizb Ullah, Tayyaba Afsar, Ghazala Shaheen and Ali Almajwal

    Citation: Journal of Ovarian Research 2016 9:86

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  39. Content type: Research

    No consensus exists on the outcome-related factors of interval debulking surgery (IDS) in patients with advanced high-grade serous ovarian cancer (HG-SOC) who underwent neoadjuvant chemotherapy (NAC). This stu...

    Authors: Xia Xu, Fei Deng, Mengmeng Lv, Binhui Ren, Wenwen Guo and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2016 9:85

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  40. Content type: Research

    Key features of advanced ovarian cancer include metastasis via cell clusters in the abdominal cavity and increased chemoresistance. Resveratrol and derivatives of resveratrol have been shown to have antitumour...

    Authors: Alexandria B. Tino, Kenny Chitcholtan, Peter H. Sykes and Ashley Garrill

    Citation: Journal of Ovarian Research 2016 9:84

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  41. Content type: Research

    Ovarian serous carcinoma (OSC) is the most common ovarian epithelial malignancy. Disregulation of Eph/ephrin signaling has been implicated in oncogenesis and tumor progression. EphA5 receptor is one of large f...

    Authors: Xiao Chen, Xuan Wang, Xue Wei and Jiandong Wang

    Citation: Journal of Ovarian Research 2016 9:83

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