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  1. Content type: Research

    PCOs is a heterogeneous disorder with anovulation/oligo ovulation usually taken as oligo menorrhoea or amenorrhoea, hyperandrogenemia, hirsutism, acne, androgen alopecia and polycystic ovaries as the key diagn...

    Authors: Asad Ullah, Sarwat Jahan, Suhail Razak, Madeeha Pirzada, Hizb Ullah, Ali Almajwal, Naveed Rauf and Tayyaba Afsar

    Citation: Journal of Ovarian Research 2017 10:62

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  2. Content type: Research

    Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a natural antioxidant polyphenol able to exert a wide range of biological effect on several tissues. Despite its important beneficial properties, it has a low ...

    Authors: Francesca Uberti, Vera Morsanuto, Silvio Aprile, Sabrina Ghirlanda, Ian Stoppa, Andrea Cochis, Giorgio Grosa, Lia Rimondini and Claudio Molinari

    Citation: Journal of Ovarian Research 2017 10:61

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  3. Content type: Research

    Upregulation of Cyclin dependent kinase 1 (CDK1) protein is closely related with the prognosis of several malignant tumors. Chk1-CDC25C-CDK1 signaling and P53-P21WAF1-CDK1 signaling pathways are closely relate...

    Authors: Ruitao Zhang, Huirong Shi, Fang Ren, Minghui Zhang, Pengcheng Ji, Wenwen Wang and Chuanna Liu

    Citation: Journal of Ovarian Research 2017 10:60

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  4. Content type: Research

    The purpose of this study is to examine whether racial disparities in epithelial ovarian cancer stage at diagnosis and survival may be explained by geographic availability of healthcare resources among Blacks ...

    Authors: Swati Sakhuja, Huifeng Yun, Maria Pisu and Tomi Akinyemiju

    Citation: Journal of Ovarian Research 2017 10:57

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  5. Content type: Research

    Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primor...

    Authors: Linyan Zhou, Yanqiu Xie, Song Li, Yihua Liang, Qi Qiu, Haiyan Lin and Qingxue Zhang

    Citation: Journal of Ovarian Research 2017 10:56

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  6. Content type: Research

    There is no universal screening method for discrimination between benign and malignant adnexal masses yet. Various authors have tried tumor markers, imaging studies, cytology but no one yet is a definite metho...

    Authors: Santosh Kumar Dora, Atal Bihari Dandapat, Benudhar Pande and Jatindra Prasad Hota

    Citation: Journal of Ovarian Research 2017 10:55

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  7. Content type: Research

    Small leucine-rich proteoglycans (SLRPs) play an important role in tissue homeostasis and cell proliferation since these proteoglycans sequester multiple growth factors. However, the content of SLRPs in the en...

    Authors: Ricardo Santos Simões, José Maria Soares-Jr, Manuel J. Simões, Helena B. Nader, Maria Cândida P. Baracat, Gustavo Arantes R. Maciel, Paulo C. Serafini, Ricardo Azziz and Edmund C. Baracat

    Citation: Journal of Ovarian Research 2017 10:54

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  8. Content type: Research

    Ovarian carcinoma is highly dependent on the ubiquitin proteasome system (UPS), but its clinical response to treatment with the proteasome inhibitor bortezomib has been disappointing. This has driven explorati...

    Authors: Rosie T. Jiang, Anna Yemelyanova, Deyin Xing, Ravi K. Anchoori, Jun Hamazaki, Shigeo Murata, Jeffrey D. Seidman, Tian-Li Wang and Richard B. S. Roden

    Citation: Journal of Ovarian Research 2017 10:53

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  9. Content type: Research

    To retrospectively investigate reproductive outcomes after fertility-sparing surgery and postoperative adjuvant chemotherapy in malignant ovarian germ cell tumors (MOGCT) and sex cord-stromal tumors (SCST).

    Authors: Ning Zhang, Ruifang Chen, Keqin Hua and Ying Zhang

    Citation: Journal of Ovarian Research 2017 10:52

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  10. Content type: Research

    R-spondin2 (Rspo2) is a secreted agonist of the canonical Wnt/β-catenin signaling pathway. Rspo2 plays a key role in development of limbs, lungs and hair follicles, and more recently during ovarian follicle de...

    Authors: Justine Bouilly, Isabelle Beau, Sara Barraud, Valérie Bernard, Brigitte Delemer, Jacques Young and Nadine Binart

    Citation: Journal of Ovarian Research 2017 10:51

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  11. Content type: Research

    Discoidin Domain Receptor 1 (DDR1) belongs to the family of collagen receptor tyrosine kinases that confers the progression of various cancers. Aberrant expression of DDR1 was detected in several human cancers...

    Authors: Yuao Deng, Fang Zhao, Liu Hui, Xiuyun Li, Danyu Zhang, Wang Lin, Zhiqiang Chen and Yingxia Ning

    Citation: Journal of Ovarian Research 2017 10:50

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  12. Content type: Research

    Ovarian cancer is one of the three leading gynecological malignancies, characterized by insidious growth, highly frequent metastasis, and quick development of drug resistance. As a result, this disease has low...

    Authors: Huidi Liu, Jianrui Liu, Siwen Wang, Zheng Zeng, Ting Li, Yongfang Liu, Emilio Mastriani, Qing-Hai Li, Hong-Xia Bao, Yu-Jie Zhou, Xiaoyu Wang, Sijing Hu, Shan Gao, Yingying Qi, Zhihang Shen, Hongyue Wang…

    Citation: Journal of Ovarian Research 2017 10:49

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  13. Content type: Research

    An upward trending incidence in cervical adenocarcinoma (ADC) has been reported in many countries. Because non-squamous histology has been associated with increased risk of ovarian metastases (OM), bilateral o...

    Authors: Jiansong Zhou, Yuanyuan Chen, Ping Zhang and Hanmei Lou

    Citation: Journal of Ovarian Research 2017 10:48

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  14. Content type: Research

    In human IVF, embryos cultured with a lower O2 tension (5%) can give rise to higher success rates when compared with normoxic conditions (20%). However, the mechanisms behind the beneficial effects of reduced oxy...

    Authors: Yun-Yi Ma, Huei-Wen Chen and Chii-Ruey Tzeng

    Citation: Journal of Ovarian Research 2017 10:47

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  15. Content type: Case report

    Choriocarcinoma of the ovary is rare. This tumor can arise from gestational tissue or pure germ cells of the ovary, the former results in gestational choriocarcinoma. The clinical characteristics and histology...

    Authors: Nan Jia, Yan Chen, Xiang Tao, Enzhi Ou, Xin Lu and Weiwei Feng

    Citation: Journal of Ovarian Research 2017 10:46

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  16. Content type: Research

    To explore the risk factors of endometriosis-associated ovarian cancer (EAOC) in women with ovarian endometriosis (OEM) aged 45 years and above in China.

    Authors: Zheng-Xing He, Hong-Hui Shi, Qing-Bo Fan, Lan Zhu, Jin-Hua Leng, Da-Wei Sun, Zhan-Fei Li, Keng Shen, Shu Wang and Jing-He Lang

    Citation: Journal of Ovarian Research 2017 10:45

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  17. Content type: Review

    As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cell...

    Authors: Cláudia Freitas, Ana Catarina Neto, Liliana Matos, Elisabete Silva, Ângela Ribeiro, João Luís Silva-Carvalho and Henrique Almeida

    Citation: Journal of Ovarian Research 2017 10:44

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  18. Content type: Review

    Endometriosis is an estrogen-dependent chronic inflammatory condition that affects women in their reproductive period causing infertility and pelvic pain. The disease, especially at the ovarian site has been s...

    Authors: Ana Maria Sanchez, Valeria Stella Vanni, Ludovica Bartiromo, Enrico Papaleo, Eran Zilberberg, Massimo Candiani, Raoul Orvieto and Paola Viganò

    Citation: Journal of Ovarian Research 2017 10:43

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  19. Content type: Research

    Oocyte quality is a key limiting factor in female fertility which is primarily reflected in morphological features. Centrally located cytoplasm granulation (CLCG) is one type of cytoplasmic dimorphism exhibite...

    Authors: Philippe Merviel, Rosalie Cabry, Karen Chardon, Elodie Haraux, Florence Scheffler, Naima-belhadri Mansouri, Aviva Devaux, Hikmat Chahine, Véronique Bach, Henri Copin and Moncef Benkhalifa

    Citation: Journal of Ovarian Research 2017 10:42

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  20. Content type: Research

    Ovarian hyperstimulation syndrome (OHSS) is a disorder associated with elevated serum VEGFA following chorionic gonadotropin (hCG) exposure in controlled ovarian stimulation (COS) cycles in women. In this stud...

    Authors: C. V. Bishop, D. M. Lee, O. D. Slayden and X. Li

    Citation: Journal of Ovarian Research 2017 10:41

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  21. Content type: Research

    MMP-7 and TIMP-1 may play a role in the pathogenesis of cancer disease. In this study we investigated plasma levels of selected metalloproteinase and its tissue inhibitor in comparison to plasma levels of the ...

    Authors: Grażyna Ewa Będkowska, Ewa Gacuta, Monika Zajkowska, Edyta Katarzyna Głażewska, Joanna Osada, Maciej Szmitkowski, Lech Chrostek, Milena Dąbrowska and Sławomir Ławicki

    Citation: Journal of Ovarian Research 2017 10:39

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  22. Content type: Research

    Ovarian tissue cryopreservation is a technique for fertility preservation addressed to prepubertal girls or to patients for whom no ovarian stimulation is possible before initiation of gonadotoxic treatments. ...

    Authors: Tristan Zver, Elodie Mouloungui, Aurélie Berdin, Christophe Roux and Clotilde Amiot

    Citation: Journal of Ovarian Research 2017 10:38

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  23. Content type: Research

    Oocyte maturation and preimplantation embryo development are controlled by array of genes that are post-transcriptionally regulated by microRNAs. With respect to this, previously, we identified altered express...

    Authors: Pritam Bala Sinha, Dawit Tesfaye, Franca Rings, Munir Hossien, Michael Hoelker, Eva Held, Christaine Neuhoff, Ernst Tholen, Karl Schellander and Dessie Salilew-Wondim

    Citation: Journal of Ovarian Research 2017 10:37

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  24. Content type: Research

    The survival duration of elderly patients with epithelial ovarian carcinoma is shorter than that of their younger counterparts. This variation in survival duration is likely attributed to differences in the di...

    Authors: Fei Deng, Xia Xu, Mengmeng Lv, Binhui Ren, Yan Wang, Wenwen Guo, Jifeng Feng and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2017 10:36

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  25. Content type: Research

    We aimed to test the hypothesis that the correlation of the changes in the blood Androstenedione (A4) levels to the number of selected follicles during ovulation induction with low-dose recombinant human follicle...

    Authors: Eser Sefik Ozyurek, Tevfik Yoldemir and Gokhan Artar

    Citation: Journal of Ovarian Research 2017 10:34

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  26. Content type: Research

    Ovarian cancer is the leading lethal, gynecological malignancy in the United States. No doubt, the continued morbidity and mortality of ovarian cancer reflects a poor understanding of invasive mechanisms. Rece...

    Authors: Jun Wei, Lahong Zhang, Jennifer Li, Shuguang Zhu, Minghui Tai, Clifford W. Mason, Julia A. Chapman, Evelyn A. Reynolds, Carl P Weiner and Helen H Zhou

    Citation: Journal of Ovarian Research 2017 10:33

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  27. Content type: Research

    Diminished ovarian reserve(DOR) is associated with female infertility and poor response to ovarian stimulation. Our objective was to assess the effect of dehydroepiandrosterone(DHEA) on DOR women and to explor...

    Authors: Qiaofei Hu, Liming Hong, Mingyue Nie, Qin Wang, Ying Fang, Yinmei Dai, Yanhong Zhai, Shuyu Wang, Chenghong Yin and Xiaokui Yang

    Citation: Journal of Ovarian Research 2017 10:32

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  28. Content type: Research

    Ovarian cancer is the leading cause of death for gynecological cancers and the 6th cause of women cancer death in developed countries. The late stage detection, the peritoneal dissemination and the acquisition...

    Authors: Benoît Thibault and Bertrand Jean-Claude

    Citation: Journal of Ovarian Research 2017 10:31

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  29. Content type: Research

    Accumulated evidence has demonstrated that Mammalian hepatitis B X-interacting protein (HBXIP) has broad roles in cancer. Although HBXIP is associated with a variety of cancers, the HBXIP protein expression le...

    Authors: Yixuan Wang, Jie Sun, Nan Li, Shuanlong Che, Tiefeng Jin, Shuangping Liu and Zhenhua Lin

    Citation: Journal of Ovarian Research 2017 10:26

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  30. Content type: Case report

    Although immune system plays a key role in the pathogenesis of both endometriosis and ovarian cancer, its function is different. Therefore, we hypothesized, that selected immune parameters can serve as diagnos...

    Authors: Olimpia Sipak-Szmigiel, Piotr Włodarski, Elżbieta Ronin-Walknowska, Andrzej Niedzielski, Beata Karakiewicz, Sylwia Słuczanowska-Głąbowska, Maria Laszczyńska and Witold Malinowski

    Citation: Journal of Ovarian Research 2017 10:25

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  31. Content type: Research

    Resistance to platinum-based chemotherapy remains a great challenge for ovarian cancer treatment. The human let-7 family contains 13 members located on nine different chromosomes, and most members have been im...

    Authors: Man Xiao, Jing Cai, Liqiong Cai, Jinghui Jia, Lisha Xie, Ying Zhu, Bangxing Huang, Dongdong Jin and Zehua Wang

    Citation: Journal of Ovarian Research 2017 10:24

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  32. Content type: Research

    The lack of consensus around best practices for management of borderline ovarian tumors (BOT) is, in part, to the lack of available data and of clarity in interpreting relationships among various factors that ...

    Authors: Xi Chen, Chenyan Fang, Tao Zhu, Ping Zhang, Aijun Yu and Shihua Wang

    Citation: Journal of Ovarian Research 2017 10:23

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  33. Content type: Brief Communication

    Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecu...

    Authors: Wen-Chung Wang, Ya-Ting Lee and Yen-Chein Lai

    Citation: Journal of Ovarian Research 2017 10:22

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  34. Content type: Research

    Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening.

    Authors: Renée T. Fortner, Allison F. Vitonis, Helena Schock, Anika Hüsing, Theron Johnson, Raina N. Fichorova, Titilayo Fashemi, Hidemi S. Yamamoto, Anne Tjønneland, Louise Hansen, Kim Overvad, Marie-Christine Boutron-Ruault, Marina Kvaskoff, Gianluca Severi, Heiner Boeing, Antonia Trichopoulou…

    Citation: Journal of Ovarian Research 2017 10:20

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  35. Content type: Research

    There is substantial evidence both in humans and in animals that a prolonged reduction in plasma thyroid hormone concentration leads to reproductive problems, including disturbed folliculogenesis, impaired ovu...

    Authors: Li Meng, Eddy Rijntjes, Hans J. M. Swarts, Jaap Keijer and Katja J. Teerds

    Citation: Journal of Ovarian Research 2017 10:19

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  36. Content type: Research

    In this work, a detailed anatomical description of the ovarian plexus nerve (OPN) in rats is presented. The distribution of the OPN was analyzed by gross anatomy; the features of the superior mesenteric gangli...

    Authors: César F. Pastelín, Nora H. Rosas, Leticia Morales-Ledesma, Rosa Linares, Roberto Domínguez and Carolina Morán

    Citation: Journal of Ovarian Research 2017 10:18

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  37. Content type: Case report

    Mature cystic teratomas are usually found in the ovaries. They are bilateral in 10 to 15% of cases and multiple cystic teratomas may be present in one ovary. The aim of this study is to clarify if development ...

    Authors: Wen-Chung Wang and Yen-Chein Lai

    Citation: Journal of Ovarian Research 2017 10:17

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  38. Content type: Case report

    Cytochrome P450 oxidoreductase deficiency (PORD) is a rare disease exhibiting a variety of clinical manifestations. It can be difficult to differentiate with other diseases such as 21-hydroxylase deficiency (2...

    Authors: Yang Bai, Jinhui Li and Xiaoli Wang

    Citation: Journal of Ovarian Research 2017 10:16

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  39. Content type: Research

    Preoperative evaluation of ovarian tumors is challenging. This study was undertaken to evaluate the performance of conventional two-dimensional (2D) ultrasound and CA125 in predicting malignant or benign natur...

    Authors: Riikka Johanna Niemi, Sami Kristian Saarelainen, Tiina Hannele Luukkaala and Johanna Unelma Mäenpää

    Citation: Journal of Ovarian Research 2017 10:15

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  40. Content type: Research

    The detection of CA125 has been used in the follow up of ovarian cancer. At present, some scholars believe that serum CA125 has no clinical value for the follow-up monitoring the recurrence for postoperative p...

    Authors: Na Guo and Zhilan Peng

    Citation: Journal of Ovarian Research 2017 10:14

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  41. Content type: Review

    In adults, the ovary is characterized with extensive angiogenesis and regular intervals of rapid growth. Ovarian function is dependent on the network of angiogenic vessels which enable the follicle and/or corp...

    Authors: Qi Xie, Zuowang Cheng, Xiaocui Chen, Corrinne G. Lobe and Ju Liu

    Citation: Journal of Ovarian Research 2017 10:13

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