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  1. Polycystic ovary syndrome (PCOS) is a common reproductive, neuroendocrine, and metabolic disorder in women of reproductive age that affects up to 5–10% of women of reproductive age. The aetiology of follicle d...

    Authors: Qingfang Li, Yimiao Sang, Qingqing Chen, Bingru Ye, Xiaoqian Zhou and Yimin Zhu
    Citation: Journal of Ovarian Research 2023 16:154
  2. Sclerosing stromal tumors of the ovary are benign and tend to occur in youthful women with lobular structures at low frequencies. Three types of cells, including luteinized cells, short spindle myoid cells, an...

    Authors: Li Zhao, Zhongfeng Yang, Yan Zhou, Yuping Liu, Qiuping Luo, Qingping Jiang, Hui Wang and Na Wang
    Citation: Journal of Ovarian Research 2023 16:152
  3. Excessive production of androgen drives oxidative stress (OS) and inflammasome activation in ovarian granulosa cells (GCs). Therefore, the induced follicular developmental disorder is the major cause of infert...

    Authors: Yajing Weng, Yaling Zhang, Daojuan Wang, Rong Wang, Zou Xiang, Shanmei Shen, Hongwei Wang, Xiaoke Wu, Yanting Wen and Yong Wang
    Citation: Journal of Ovarian Research 2023 16:151
  4. Mechanisms of development and progression of high-grade serous ovarian cancer (HGSOC) are poorly understood. EVI1 and PARP1, part of TGF-ß pathway, are upregulated in cancers with DNA repair deficiencies with ...

    Authors: Paul Jank, Jonas Leichsenring, Svenja Kolb, Inga Hoffmann, Philip Bischoff, Catarina Alisa Kunze, Mihnea P. Dragomir, Moritz Gleitsmann, Moritz Jesinghaus, Wolfgang D. Schmitt, Hagen Kulbe, Christine Sers, Albrecht Stenzinger, Jalid Sehouli, Ioana Elena Braicu, Christina Westhoff…
    Citation: Journal of Ovarian Research 2023 16:150
  5. Polycystic ovary syndrome (PCOS) is known as a prevalent but complicated gynecologic disease throughout the reproductive period. Typically, it is characterized by phenotypic manifestations of hyperandrogenism,...

    Authors: Yuli Geng, Zhuo Liu, Runan Hu, Wenwen Ma, Xiao Wu, Haoxu Dong, Kunkun Song, Xiaohu Xu, Yanjing Huang, Fan Li, Yufan Song and Mingmin Zhang
    Citation: Journal of Ovarian Research 2023 16:149
  6. Over the past two decades, increasing number of people with cystic fibrosis (CF) survive into adulthood. Compared to the general population, sub-fertility is an obstacle for many women with CF (wwCF). Decrease...

    Authors: Malena Cohen-Cymberknoh, Keren Marks Garber, Joel Reiter, Michal Shteinberg, Aielet Stolovas, Iyad Barghouti, Chana Adler Lazarovits, Efrat Esh Broder and Anat Hershko Klement
    Citation: Journal of Ovarian Research 2023 16:148
  7. A recent study reported the role of long non-coding RNA (lncRNA) RBAT1 in promoting the development of retinoblastoma and bladder cancer. However, its function in other cancers is unclear. We then studied the ...

    Authors: Lingye Fan, Chunyan Wang, Ping Zhan and Yaofang Liu
    Citation: Journal of Ovarian Research 2023 16:147
  8. To establish an early clinical diagnosis model based on the retinal vascular features associated with POI, supplying a non-invasive way for accurately and early predicted the risk of POI.

    Authors: Jiaman Wu, Liya Tan, Yan Ning, Weiqu Yuan, Zuowei Lee, Fei Ma, Erfeng Wang and Yuanyuan Zhuo
    Citation: Journal of Ovarian Research 2023 16:146
  9. Granulosa cells (GCs) that surround oocytes in mammalian reproduction play an active role in oocyte differentiation through proliferation and energy production.

    Authors: Ya-Kun Zhao, Ya-Na Gao, Ling-Chao Wang, Jing Wang, Gai-Jing Wang and Hong-Li Wu
    Citation: Journal of Ovarian Research 2023 16:145
  10. The current study attempted to investigate the role of transcription factor c-fos in the development of premature ovarian insufficiency (POI) as well as the underlying mechanism involving the MALAT1/miR-22-3p/...

    Authors: Ting Qiu, Jie Zhou, Bing Ji, Liuyang Yuan, Tingsong Weng and Huishu Liu
    Citation: Journal of Ovarian Research 2023 16:144
  11. To explore the effect of intervention programs constructed under the guidance of the comprehensive unit-based safety program (CUSP) model on chemotherapy-induced nausea and vomiting (CINV) in patients with ova...

    Authors: Aihua Liu, Min Li, Zhuo Liu, Xinxin Xie, Wen Yao, Jingmin Wang, Tingting Zhao and Jie Yang
    Citation: Journal of Ovarian Research 2023 16:143
  12. Accumulating studies have reported indispensable functions of circular RNAs (circRNA) in tumor progression through regulation of gene expression. However, circRNA expression profiles and functions in human ova...

    Authors: Hongxia Wang, Suwei Lan, Lingxiang Wang, Jingyun Zhao, Xinzhuan Jia, Jie Xu, Guangyu Sun, Leilei Liu, Shan Gong, Na Wang, Baoen Shan, Fenghua Zhang and Zhengmao Zhang
    Citation: Journal of Ovarian Research 2023 16:142
  13. High-grade serous ovarian cancers (HGSCs) display a high degree of complex genetic alterations. In this study, we identified germline and somatic genetic alterations in HGSC and their association with relapse-...

    Authors: A. W. Adamson, Y. C. Ding, L. Steele, L. A. Leong, R. Morgan, M. T. Wakabayashi, E. S. Han, T. H. Dellinger, P. S. Lin, A. A. Hakim, S. Wilczynski, C. D. Warden, S. Tao, V. Bedell, M. C. Cristea and S. L. Neuhausen
    Citation: Journal of Ovarian Research 2023 16:141
  14. Thyroid autoimmunity and polycystic ovary syndrome (PCOS) are the most common endocrinopathies and have close relationships based on common etiology and pathogenesis, including genetic susceptibility, metaboli...

    Authors: Huahua Jiang, Lixue Chen, Ning Huang, Huifeng Shi, Hongbin Chi, Rui Yang, Xiaoyu Long and Jie Qiao
    Citation: Journal of Ovarian Research 2023 16:140
  15. The specific long-term trend in ovarian cancer (OC) rates in China has been rarely investigated. We aimed to estimate the temporal trends in incidence and mortality rates from 1990 to 2019 in OC and predict th...

    Authors: Jianyang Feng, Lijiang Xu, Yangping Chen, Rongjin Lin, Haoxian Li and Hong He
    Citation: Journal of Ovarian Research 2023 16:139
  16. Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder that frequently exhibits low-grade inflammation, pro-oxidant activity, and gut dysbiosis. PCOS has become one of the leading causes ...

    Authors: Hong Zhang, Lu Zheng, Chuwei Li, Jun Jing, Zhou Li, Shanshan Sun, Tongmin Xue, Kemei Zhang, Mengqi Xue, Chun Cao, Lei Ouyang, Zhang Qian, Rui Xu, Zhaowanyue He, Rujun Ma, Li Chen…
    Citation: Journal of Ovarian Research 2023 16:138
  17. Folliculogenesis is a complex network of interacting cellular signals between somatic cells and oocytes. Many components in ovarian follicular fluid (FF) dynamically change during folliculogenesis and play a p...

    Authors: Jia Liu and Chong Wang
    Citation: Journal of Ovarian Research 2023 16:137
  18. Paclitaxel dose-dense regimen has been controversial in clinical trials in recent years. This systematic review and meta-analysis tried to evaluate the efficacy and safety of paclitaxel dose-dense chemotherapy...

    Authors: Wenjian Gong, Ruidi Yu, Canhui Cao, Yong Fang, Xuejiao Zhao and Qinglei Gao
    Citation: Journal of Ovarian Research 2023 16:136
  19. Premature ovarian insufficiency (POI) is a clinically heterogeneous disease that may seriously affect the physical and mental health of women of reproductive age. POI primarily manifests as ovarian function de...

    Authors: Xuechun Ding, Xiaowei Gong, Yingying Fan, Jinghe Cao, Jingyu Zhao, Yixin Zhang, Xiaomei Wang and Kai Meng
    Citation: Journal of Ovarian Research 2023 16:135
  20. Cangfu Daotan Wan (CFDTW) has been widely used for polycystic ovary syndrome (PCOS) patients in the type of stagnation of phlegm and dampness. In this study, we aimed to evaluate the mechanism underlying the t...

    Authors: Yuan Li, Haicui Wu, Ying Guo, Chaofeng Wei, Lu Guan, Wenhan Ju and Fang Lian
    Citation: Journal of Ovarian Research 2023 16:134
  21. Multiple-organ primary tumors can invade the ovary through lymphatic and hematogenous routes, presenting as ovarian Krukenberg tumors, but these rarely originate from the gallbladder. Krukenberg tumors can pre...

    Authors: Jing Wang, Yanjun Liu, Liang Sang and Weina Wan
    Citation: Journal of Ovarian Research 2023 16:133
  22. When prepubertal lambs are superovulated, the ovarian response to gonadotropin stimulation has great individual difference and the collected oocytes have lower developmental ability than that of adult ewes. Ov...

    Authors: Kexiong Liu, Luyao Zhang, Qi Qi, Junjin Li, Fengxiang Yan and Jian Hou
    Citation: Journal of Ovarian Research 2023 16:132
  23. Telomeres are repetitive DNA sequences at eukaryotic chromosome ends and function in maintaining genome integrity and stability. These unique structures undergo shortening due to various factors including biol...

    Authors: Betul Tire and Saffet Ozturk
    Citation: Journal of Ovarian Research 2023 16:130
  24. Endometrial carcinoma (EC) is the sixth most frequent malignancy in women and is often linked to high estrogen exposure. Polycystic ovarian syndrome (PCOS) is a known risk factor for EC, but the underlying mec...

    Authors: Yun Zhang, Yifang Hu, Jian Yu, Xiaoyan Xie, Feng Jiang and Chuyan Wu
    Citation: Journal of Ovarian Research 2023 16:129
  25. Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder in women of reproductive age that still lacks effective treatment. Inflammation is one of the important features of PCOS. Asparagus ...

    Authors: Jinshan Xing, Xin Luo, Keran Jia, Shuang Liu, Shaokun Chen, Gan Qiao, Chunxiang Zhang and Jingyan Yi
    Citation: Journal of Ovarian Research 2023 16:128
  26. Advanced glycation end products (AGEs) are known to associate with the pathogenesis of several chronic diseases via interaction with their corresponding receptor (RAGE). The soluble forms of RAGE (sRAGE) are c...

    Authors: Neda Emami, AliReza Alizadeh, Arezoo Maleki-Hajiagha, Alireza Dizavi, Samira Vesali and Ashraf Moini
    Citation: Journal of Ovarian Research 2023 16:127
  27. Ovarian cancer (OC) is one of the most common malignancies in women. It has a poor prognosis owing to its recurrence and metastasis. Unfortunately, reliable markers for early diagnosis and prognosis of OC are ...

    Authors: Zouyu Zhao, Chongfeng Sun, Jishuai Hou, Panpan Yu, Yan Wei, Rui Bai and Ping Yang
    Citation: Journal of Ovarian Research 2023 16:126
  28. Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women at increased risk of breast and ovarian cancer. We launched a prospective study of women receiving RRSO, including those with mutations in ge...

    Authors: Zheng Feng, Ke Zuo, Xingzhu Ju, Xiaojun Chen, Wentao Yang, Hao Wen, Lin Yu and Xiaohua Wu
    Citation: Journal of Ovarian Research 2023 16:125
  29. MicroRNAs are a group of small non-coding RNAs that are involved in development and diseases such as cancer. Previously, we demonstrated that miR-335 is crucial for preventing collagen type XI alpha 1 (COL11A1...

    Authors: Yi-Hui Wu, Yu-Fang Huang, Pei-Ying Wu, Tzu-Hao Chang, Soon-Cen Huang and Cheng-Yang Chou
    Citation: Journal of Ovarian Research 2023 16:124
  30. To analyze whether metformin treatment in patients with polycystic ovary syndrome (PCOS) results in a decrease of anti-Müllerian hormone (AMH) levels, we reviewed and analyzed PCOS studies which evaluated seru...

    Authors: Zhijiao Zhou, Hongzhi Chen, Ling Chu, Qiong Zou, Qian Chen, Jun Yang, Yang Liu and Xiang Ou
    Citation: Journal of Ovarian Research 2023 16:123
  31. Poly-ADP Ribose Polymerase (PARP) targeted therapy is clinically approved for the treatment of homologous recombination (HR) repair deficient tumors. The remarkable success of this therapy in the treatment of ...

    Authors: Goutam Dey, Rashmi Bharti, Chad Braley, Ravi Alluri, Emily Esakov, Katie Crean-Tate, Keith McCrae, Amy Joehlin-Price, Peter G. Rose, Justin Lathia, Zihua Gong and Ofer Reizes
    Citation: Journal of Ovarian Research 2023 16:122
  32. To investigate the prognostic relevance of the time to interval debulking surgery (TTS) and the time to postoperative adjuvant chemotherapy (TTC) after the completion of neoadjuvant chemotherapy (NACT).

    Authors: Xingyu Liu, Yingjun Zhao, Xiaofei Jiao, Yang Yu, Ruyuan Li, Shaoqing Zeng, Jianhua Chi, Guanchen Ma, Yabing Huo, Ming Li, Zikun Peng, Jiahao Liu, Qi Zhou, Dongling Zou, Li Wang, Qingshui Li…
    Citation: Journal of Ovarian Research 2023 16:121
  33. Mucinous epithelial ovarian cancer (mEOC) is a relatively uncommon subtype of ovarian cancer with special prognostic features, but there is insufficient research in this area. This study aimed to develop a nom...

    Authors: Guanchen Ma, Shaoqing Zeng, Yingjun Zhao, Jianhua Chi, Li Wang, Qingshui Li, Jing Wang, Shuzhong Yao, Qi Zhou, Youguo Chen, Xiaofei Jiao, Xingyu Liu, Yang Yu, Yabing Huo, Ming Li, Zikun Peng…
    Citation: Journal of Ovarian Research 2023 16:120
  34. A premature luteinizing hormone (LH) surge refers to an endogenous LH peak that occurs before follicle maturation or human chorionic gonadotropin injection in the process of controlled ovarian hyperstimulation...

    Authors: Yangyang Zhang, Yang Xu, Jiao Yu, Xi Wang, Qing Xue, Jing Shang, Xiuli Yang and Xuemin Shan
    Citation: Journal of Ovarian Research 2023 16:119
  35. In the current study, we investigated the regenerative effects of amniotic fluid exosomes (AF-Exos) in a rat model for premature ovarian insufficiency (POI). POI is a condition characterized by a decrease in o...

    Authors: Nahideh Nazdikbin Yamchi, Shahin Ahmadian, Halimeh Mobarak, Farhad Amjadi, Rahim Beheshti, Amin Tamadon, Reza Rahbarghazi and Mahdi Mahdipour
    Citation: Journal of Ovarian Research 2023 16:118
  36. Increasingly studies reported that the Anti-Müllerian hormone (AMH) seems to be a promising and reliable marker of functional ovarian follicle reserve, even better than the AFC test. Our study aimed to conduct...

    Authors: Yang Liu, Zhengmei Pan, Yanzhi Wu, Jiamei Song and Jingsi Chen
    Citation: Journal of Ovarian Research 2023 16:117
  37. Reproductive traits play a vital role in determining the production efficiency of sheep. Maximizing the production is of paramount importance for breeders worldwide due to the growing population. Circular RNAs...

    Authors: Salsabeel Yousuf, Waqar Afzal Malik, Hui Feng, Tianyi Liu, Lingli Xie and Xiangyang Miao
    Citation: Journal of Ovarian Research 2023 16:115
  38. Ovarian cancer is the third most prevalent cancer in Indian women. Relative frequency of High grade serous epithelial ovarian cancer (HGSOC) and its associated deaths are highest in India which suggests the im...

    Authors: Pavan Kumar, Samruddhi Ranmale, Sanket Mehta, Hemant Tongaonkar, Vainav Patel, Amit Kumar Singh and Jayanti Mania-Pramanik
    Citation: Journal of Ovarian Research 2023 16:114
  39. Exosomal circRNA, as an essential mediator of the follicular microenvironment, has been implicated in the etiological and pathobiological studies of polycystic ovarian syndrome (PCOS). This study aimed to dete...

    Authors: Li Yu, Chen Wang, Doudou Zhang, Miao Liu, Te Liu, Baishen Pan, Qi Che, Suying Liu, Beili Wang, Xi Dong and Wei Guo
    Citation: Journal of Ovarian Research 2023 16:113
  40. Granulosa cell tumors (GCTs) account for approximately 2% of ovarian malignancies and are considered a rare type of ovarian cancer. GCTs are characterized by irregular genital bleeding after menopause due to f...

    Authors: Kazuki Takasaki, Takayuki Ichinose, Yuko Miyagawa, Shiho Fukui, Kei Hashimoto, Haruka Nishida, Yuko Takahashi, Haruko Hiraike, Koji Saito, Yuko Sasajima and Kazunori Nagasaka
    Citation: Journal of Ovarian Research 2023 16:112
  41. 17α-hydroxylase/17,20-lyase deficiency (17-OHD) is a rare form of congenital adrenal hyperplasia caused by CYP17A1 gene variants. Female patients with 17-OHD demonstrate a broad clinical spectrum, including oligo...

    Authors: Ping Pan, Lingyan Zheng, Jia Huang, Xiaoli Chen, Renmin Ni, Qingxue Zhang, Dongzi Yang and Yu Li
    Citation: Journal of Ovarian Research 2023 16:111
  42. This study aimed to compare the characteristics of the gut microbiota and their metabolite profiles between polycystic ovary syndrome (PCOS) and orlistat-treated PCOS rats (ORL-PCOS), which could help to bette...

    Authors: Jianmei Yang, Enli Wang, Mingmin Jiang, Yujun Tan, Fangfang Yao, Chenghong Sun, Lihong Pan, Ling Gao and Jingchun Yao
    Citation: Journal of Ovarian Research 2023 16:109
  43. The mortality rate of epithelial ovarian cancer (EOC) remains the first in malignant tumors of the female reproductive system. The characteristics of rapid proliferation, extensive implanted metastasis, and tr...

    Authors: Ming Wang, Jingjing Zhang and Yumei Wu
    Citation: Journal of Ovarian Research 2023 16:108
  44. Poor ovarian responders (POR) are women undergoing in-vitro fertilization who respond poorly to ovarian stimulation, resulting in the retrieval of lower number of oocytes, and subsequently lower pregnancy rate...

    Authors: Veronique Viardot-Foucault, Jieliang Zhou, Dexi Bi, Yoshihiko Takinami, Jerry. K. Y. Chan and Yie Hou Lee
    Citation: Journal of Ovarian Research 2023 16:107
  45. Tumor-to-tumor metastasis (TTM) is a rare but well-established phenomenon where histologically distinct tumors metastasize within each other. Here we report the first “known” case of follicular lymphoma that m...

    Authors: Yusuke Sato, Mitsutake Yano, Satoshi Eto, Kuniko Takano and Kaei Nasu
    Citation: Journal of Ovarian Research 2023 16:106
  46. Women with polycystic ovary syndrome (PCOS) suffer from a wide range of psychological problems. The goal of this study is to assess depression, sexual dysfunction and sexual quality of life in women with PCO c...

    Authors: Batool Shahraki Mojahed, Mahsa Ghajarzadeh, Razie Khammar and Zahra Shahraki
    Citation: Journal of Ovarian Research 2023 16:105

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