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Circular RNAs (circRNAs) are reported to be key regulators in the progression of human cancers. This work focuses on the function and ... known as hsa_circ_0008732) in ovarian cancer (OC).
This study intended to clarify the mechanisms by which WISP1-mediated IGF1/αvβ3/Wnt axis might affect the progression of ovarian cancer.
Purine, an abundant substrate in organisms, is a critical raw material for cell proliferation and an important factor for immune regulation. The purine de novo pathway and salvage pathway are tightly regulated by...
Recently, increasing evidence has indicated that elevation of Hexokinase 2 (HK2) plays an important role in several cancers on regulating cell motility and growth. However ... role on regulating cell EMT in human...
Metastasis was the major cause of the high mortality in ovarian cancer. Although some mechanisms of metastasis in ovarian cancer were proposed, few have been targeted in ... to metastasis and poor clinical outcom...
Many factors can affect the recurrence of endometriosis after surgery, however, whether endometriotic cyst fluid contributes to endometriosis recurrence after surgical excision of ovarian endometriomas remains...
Epithelial ovarian cancer (EOC) is the most lethal gynaecological cancer among women worldwide, with the 5-year ... with homologous recombination deficiency (HRD) including BReast CAncer gene (BRCA) mutations are...
Clinical outcomes of cancer cell senescence are still elusive. Here, ... activity of spontaneously and drug-inducible senescent ovarian cancer cells. Experiments were performed on tumors and tumor-derived primary...
Granulosa cells (GCs) are multilayered somatic cells within the follicle that provide physical support and microenvironment for the developing oocyte. In recent years, the role of Neuregulin-1 (NRG1), a member...
Ovarian clear cell carcinoma (OCCC) is the most common endometriosis-associated ovarian cancer. Ovarian endometriosis may present with atypical or...
Bilateral ovarian epithelial neoplasms in adolescents are rare. Moreover, borderline mucinous neoplasms with local intraepithelial carcinoma with anaplastic carcinoma are even more infrequent. Herein, we prese...
The original article was published in Journal of Ovarian Research 2022 15:56
Ovarian cancer (OC), a frequent malignant tumor that ... , is one of the leading causes of cancer-related death in this group of individuals. For the treatment of ovarian cancer, systemic chemotherapy with platin...
The delay of ovarian aging and the fertility preservation of cancer patients are the eternal themes in the ... is also considered as the principle player of cancer, cardiovascular diseases, cerebrovascular diseas...
Ying Yang1 (YY1) has already been discussed in oral squamous cell carcinoma (OSCC), but the knowledge about its mediation on long non-coding RNA KCNQ1 overlapping transcript 1/microRNA-506-3p/synaptophysin lik...
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13048-016-0266-3.
Studies have revealed the implications of cancer-associated fibroblasts (CAFs) in tumor progression, ... pathways by which CAFs affected chemoresistance in ovarian cancer.
High grade epithelial ovarian cancer (EOC) represents a diagnostic and therapeutic...in-silico analysis. We present the analysis of 150 ovarian tissue microarray (TMA) samples on the expression of the translation...
Among many gynecological malignancies ovarian cancer is the most prominent and leading cause ... still unknown. In the progression of ovarian cancer different non-coding RNAs have been recognized as important reg...
Highly differentiated follicular carcinoma (HDFCO) is a rare form of struma-derived thyroid-type carcinoma in ovary, defined as ovarian struma spreading beyond ovary but consisting of benign thyroid tissues. N...
Mitochondrial dynamics (e.g. fission/fusion) play an important role in controlling chemoresistance in representative gynecologic malignancies, ovarian and cervical cancer. Processing the long form of Optic atroph...
Dysregulation of Ectonucleoside Triphospahate Diphosphohydrolase 5 (ENTPD5) in tumors might be associated with tumor progression, while the role of ENTPD5 in the growth and metastasis of serous ovarian cancer (SO...
Mature cystic teratomas of the ovary (MCTO) are a type of germ cell tumor that may contain well-differentiated tissues developed from three germ cell layers and constitute about 20% of ovarian germ cell tumors...
Ovarian cancer is composed of a complex system of ... , thus making it the most lethal gynecologic cancer. Seminal work on cancer as an evolutionary process has a long ... that focused on the clonal evolution of ...
Rising evidences bespeak that circular RNAs are indispensable in regulating cellular biological behaviors and engaging in diseases' occurrence. CircRHOBTB3 has been reported to participate intimately in the progr...
To evaluate the diagnostic utility of conventional magnetic resonance imaging (MRI)-based characteristics and a texture analysis (TA) for discriminating between ovarian thecoma-fibroma groups (OTFGs) and ovari...
The results showed that the number of preoperative white blood cells (p = 0.022), monocytes (p < 0.001), lymphocytes (p < 0.001), neutrophils (p < 0.001), and eosinophils (p...< 0.001) and the monocyte to lymphoc...
The prognostic value of the expression of estrogen receptor (ER) subtypes ER⍺ and ERβ in ovarian cancer has previously been evaluated by meta-analyses....
Emerging evidence identifies enhancer RNAs (eRNAs) as a class of regulatory ncRNAs that can contribute to the transcription of target genes. In this study, we used an integrated data analysis method to identify t...
Greater ovulatory years is associated with increased ovarian cancer risk. Although ovulation leads to an acute...
Circular RNA (circRNA), a class of RNA with a covalent closed circular structure that widely existed in serum and plasma, has been considered an ideal liquid biopsy marker in many diseases. In this study, we empl...
Among reproductive cancers, ovarian cancer leads to the highest female mortality rate. ... a natural flavonoid, exerts pharmacological effects, inhibiting cancer growth with various origins. Although multiple mec...
Multifaceted functions of the so-called “oncogene” Wip1 have been reported in a previous study, while its actual role remains to be explored in serous ovarian cancer (SOC). In this study, by...
The Correction to this article has been published in Journal of Ovarian Research 2022 15:82
Increasing evidence has indicated that Maelstrom (MAEL) plays an oncogenic role in various human carcinomas. However, the exact function and mechanisms by which MAEL acts in epithelial ovarian cancer (EOC) remain...
Ovarian cancer (OVC) is a devastating disease worldwide;...
Ovarian insufficiency is a major concern for long-term cancer survivors. Ovarian tissue cryopreservation for fertility preservation...
Previous studies have revealed that miRNAs participate in the pathogenesis of ovarian cancer; however, whether miR-600 is also ... investigated the role of miR-600 in ovarian cancer progression. Here, miR-600 exp...
There have been a variety of published studies on the expression of serum miR-21 in patients with ovarian cancer associated with the diagnostic value of ovarian cancer, but the conclusions are not clearly elucida...
Patients treated with neoadjuvant chemotherapy (NACT) for advanced high-grade serous ovarian carcinoma (HGSC) have a higher rate and shorter time to platinum-resistant recurrence compared to patients treated w...
Accumulated studies have provided controversial evidences of expression patterns and prognostic value of the GATA family in human ovarian cancer. In the present study, we accessed...GATA family in ovarian cancer ...
Taxol resistance in serous ovarian cancer is responsible for its poor prognosis, yet ... the mechanism of Taxol resistance in serous ovarian cancer with multiple bioinformatic methods to provide novel...
A 75-year-old female patient was reported in this study. The patient had a six-month history of changes in bowel habits, with occasional black feces and paroxysmal pain in the abdomen. The computed tomography sca...
We conducted a survey among women with ovarian cancer at their first follow-up visit or ... (MaNGO) and Multicenter Italian Trials in Ovarian Cancer (MITO) groups. A questionnaire on knowledge ... process involvi...
To investigate the alterations of peripheral lymphocyte subpopulations in ovarian cancer patients compared to benign or borderline counterparts....
Ovarian “seromucinous carcinoma” has been recently removed in 2020 5th Edition of WHO classification of Female Genital Tumors and is considered as a subtype of endometrioid carcinoma with mucinous differentiation...
Ovarian cancer (OC) is the deadliest tumor in...
We recently published evidence to suggest that two populations of stem cells including very small embryonic-like stem cells (VSELs) and ovarian stem cells (OSCs) in ovary surface epithelium (OSE) undergo proli...
The Correction to this article has been published in Journal of Ovarian Research 2023 16:165
The mammalian follicle is the basic functional unit of the ovary, and its normal development is required to obtaining oocytes capable of fertilization. As women get older or decline in ovarian function due to ...
Ovarian endometrioma is a common gynecologic disease among reproductive-aged women. Pregnancy-related hormonal status may lead to changes of decidualization, which may resemble ovarian malignancies in sonograp...
Ovarian cancer is one of the most lethal malignancies,...FEN1...gene and miR-4324 has been associated with cancer progression. However, the relationship between miR-...
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