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  1. Research

    Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort

    Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening.

    Renée T. Fortner, Allison F. Vitonis, Helena Schock, Anika Hüsing, Theron Johnson, Raina N. Fichorova, Titilayo Fashemi, Hidemi S. Yamamoto, Anne Tjønneland, Louise Hansen, Kim Overvad, Marie-Christine Boutron-Ruault, Marina Kvaskoff, Gianluca Severi, Heiner Boeing, Antonia Trichopoulou…

    Journal of Ovarian Research 2017 10:20

    Published on: 20 March 2017

  2. Research

    Reliability of preoperative evaluation of postmenopausal ovarian tumors

    Preoperative evaluation of ovarian tumors is challenging. This study was undertaken to evaluate the performance of conventional two-dimensional (2D) ultrasound and CA125 in predicting malignant or benign natur...

    Riikka Johanna Niemi, Sami Kristian Saarelainen, Tiina Hannele Luukkaala and Johanna Unelma Mäenpää

    Journal of Ovarian Research 2017 10:15

    Published on: 14 March 2017

  3. Research

    Anatomical organization and neural pathways of the ovarian plexus nerve in rats

    In this work, a detailed anatomical description of the ovarian plexus nerve (OPN) in rats is presented. The distribution of the OPN was analyzed by gross anatomy; the features of the superior mesenteric gangli...

    César F. Pastelín, Nora H. Rosas, Leticia Morales-Ledesma, Rosa Linares, Roberto Domínguez and Carolina Morán

    Journal of Ovarian Research 2017 10:18

    Published on: 14 March 2017

  4. Review

    The role of Notch signalling in ovarian angiogenesis

    In adults, the ovary is characterized with extensive angiogenesis and regular intervals of rapid growth. Ovarian function is dependent on the network of angiogenic vessels which enable the follicle and/or corp...

    Qi Xie, Zuowang Cheng, Xiaocui Chen, Corrinne G. Lobe and Ju Liu

    Journal of Ovarian Research 2017 10:13

    Published on: 11 March 2017

  5. Research

    Putative stem cells and epithelial-mesenchymal transition revealed in sections of ovarian tumor in patients with serous ovarian carcinoma using immunohistochemistry for vimentin and pluripotency-related markers

    The mechanism of aggressive character of ovarian cancer and unsuccessful treatment of women with this deadly disease has been recently explained by the theory of cancer stem cells (CSCs). It has been reported ...

    Natasa Kenda Suster, Spela Smrkolj and Irma Virant-Klun

    Journal of Ovarian Research 2017 10:11

    Published on: 23 February 2017

  6. Research

    Circulatory microRNA 23a and microRNA 23b and polycystic ovary syndrome (PCOS): the effects of body mass index and sex hormones in an Eastern Han Chinese population

    MicroRNAs (miRNAs) regulate the expression of genes involved in various cellular functions related to metabolism, inflammation, and reproduction. This study evaluated the effects of sex hormones and obesity on...

    Weixi Xiong, Ying Lin, Lili Xu, Amin Tamadon, Shien Zou, Fubo Tian, Ruijin Shao, Xin Li and Yi Feng

    Journal of Ovarian Research 2017 10:10

    Published on: 13 February 2017

  7. Research

    Naturally occurring anti-glycan antibodies binding to Globo H-expressing cells identify ovarian cancer patients

    Glycosphingolipids are important compounds of the plasma membrane of mammalian cells and a number of them have been associated with malignant transformation and progression, reinforcing tumour aggressiveness a...

    Tatiana Pochechueva, Shahidul Alam, Andreas Schötzau, Alexander Chinarev, Nicolai V. Bovin, Neville F. Hacker, Francis Jacob and Viola Heinzelmann-Schwarz

    Journal of Ovarian Research 2017 10:8

    Published on: 10 February 2017

  8. Research

    Characterization of ovarian clear cell carcinoma using target drug-based molecular biomarkers: implications for personalized cancer therapy

    It has long been appreciated that different subtypes (serous, clear cell, endometrioid and mucinous) of epithelial ovarian carcinoma (EOC) have distinct pathogenetic pathways. However, clinical management, esp...

    Mengjiao Li, Haoran Li, Fei Liu, Rui Bi, Xiaoyu Tu, Lihua Chen, Shuang Ye and Xi Cheng

    Journal of Ovarian Research 2017 10:9

    Published on: 10 February 2017

  9. Research

    Effects of a single 20 mg dose of letrozole on ovarian function post dominant follicle selection: an exploratory randomized controlled trial

    Our objective was to explore the impact of a single dose of an aromatase inhibitor (letrozole) administered at defined times of the follicular phase or immediately after ovulation on dominant follicle developm...

    H.C.M. Allaway, D.R. Chizen, G.P. Adams and R.A. Pierson

    Journal of Ovarian Research 2017 10:6

    Published on: 21 January 2017

  10. Research

    Optimal FSH usage in revascularization of allotransplanted ovarian tissue in mice

    Ovarian transplantation is a useful method for preserving the fertility of young women with cancer who undergo radiotherapy and chemotherapy. Follicle-stimulating hormone (FSH) is use to protect transplanted o...

    Wen-Zhi Ma, Xiao-Min Zheng, Chang-Chun Hei, Cheng-Jun Zhao, Sha-Sha Xie, Qing Chang, Yu-Fang Cai, Hua Jia, Xiu-Ying Pei and Yan-Rong Wang

    Journal of Ovarian Research 2017 10:5

    Published on: 17 January 2017

  11. Research

    Does the transfer of a poor quality embryo together with a good quality embryo affect the In Vitro Fertilization (IVF) outcome?

    IVF cycles which result in only one good quality embryo, and a second poor quality embryo present a dilemma when the decision involves transferring two embryos. The aim of this study was to evaluate whether a ...

    Eliana Muskin Wintner, Anat Hershko-Klement, Keren Tzadikevitch, Yehudith Ghetler, Ofer Gonen, Oren Wintner, Adrian Shulman and Amir Wiser

    Journal of Ovarian Research 2017 10:2

    Published on: 13 January 2017

  12. Research

    Quantifying growing versus non-growing ovarian follicles in the mouse

    A standard histomorphometric approach has been used for nearly 40 years that identifies atretic (e.g., dying) follicles by counting the number of pyknotic granulosa cells (GC) in the largest follicle cross-sec...

    Bahar Uslu, Carola Conca Dioguardi, Monique Haynes, De-Qiang Miao, Meltem Kurus, Gloria Hoffman and Joshua Johnson

    Journal of Ovarian Research 2017 10:3

    Published on: 13 January 2017

  13. Research

    Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats

    Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women of reproductive age. The study was commenced to assess the favorable effects of Rutin against metabolic, biochemical, histological...

    Sarwat Jahan, Faryal Munir, Suhail Razak, Anam Mehboob, Qurat Ul Ain, Hizb Ullah, Tayyaba Afsar, Ghazala Shaheen and Ali Almajwal

    Journal of Ovarian Research 2016 9:86

    Published on: 7 December 2016

  14. Research

    Ascites regression following neoadjuvant chemotherapy in prediction of treatment outcome among stage IIIc to IV high-grade serous ovarian cancer

    No consensus exists on the outcome-related factors of interval debulking surgery (IDS) in patients with advanced high-grade serous ovarian cancer (HG-SOC) who underwent neoadjuvant chemotherapy (NAC). This stu...

    Xia Xu, Fei Deng, Mengmeng Lv, Binhui Ren, Wenwen Guo and Xiaoxiang Chen

    Journal of Ovarian Research 2016 9:85

    Published on: 2 December 2016

  15. Research

    Resveratrol and acetyl-resveratrol modulate activity of VEGF and IL-8 in ovarian cancer cell aggregates via attenuation of the NF-κB protein

    Key features of advanced ovarian cancer include metastasis via cell clusters in the abdominal cavity and increased chemoresistance. Resveratrol and derivatives of resveratrol have been shown to have antitumour...

    Alexandria B. Tino, Kenny Chitcholtan, Peter H. Sykes and Ashley Garrill

    Journal of Ovarian Research 2016 9:84

    Published on: 1 December 2016

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