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  1. Target-driven cancer therapy is a notable advancement in precision oncology that has been accompanied by substantial medical accomplishments. Ovarian cancer is a highly frequent neoplasm in women and exhibits ...

    Authors: Anam Beg, Rafat Parveen, Hassan Fouad, M. E. Yahia and Azza S. Hassanein
    Citation: Journal of Ovarian Research 2024 17:86
  2. Omentectomy is an important procedure in surgery for epithelial ovarian cancer, but the scope of omentectomy is not recommended in the guidelines. This study was performed to evaluate the benefits and risks of...

    Authors: Xuhui Dong, Lei Yuan, Ruoyao Zou and Liangqing Yao
    Citation: Journal of Ovarian Research 2024 17:85
  3. Ovarian cancer, among all gynecologic malignancies, exhibits the highest incidence and mortality rate, primarily because it is often presents with non-specific or no symptoms during its early stages. For the a...

    Authors: Priyanka Gautam, Sameer Gupta and Manisha Sachan
    Citation: Journal of Ovarian Research 2024 17:83
  4. To establish a prognostic risk profile for ovarian cancer (OC) patients based on cancer-associated fibroblasts (CAFs) and gain a comprehensive understanding of their role in OC progression, prognosis, and ther...

    Authors: Liang Shen, Aihua Li, Jing Cui, Haixia Liu and Shiqian Zhang
    Citation: Journal of Ovarian Research 2024 17:82
  5. Resveratrol is a natural polyphenolic compound present in plants and red wine with many potential health benefits. This compound has various anti-inflammatory and anti-tumor properties and can improve cellular...

    Authors: A. Conforti, G. G. Iorio, R. Di Girolamo, M. Y. Rovetto, S. Picarelli, F. Cariati, R. Gentile, A. D’Amato, O. Gliozheni, B. Fioretti and C. Alviggi
    Citation: Journal of Ovarian Research 2024 17:81
  6. Chemotherapy exposure has become a main cause of premature ovarian insufficiency (POI). This study aimed to evaluate the role and molecular mechanism of human umbilical cord mesenchymal stem cell-derived exoso...

    Authors: Yuan Zhou, Jinfa Huang, Lingling Zeng, Qian Yang, Fangjuan Bai, Qiqing Mai and Kaixian Deng
    Citation: Journal of Ovarian Research 2024 17:80
  7. IR emerges as a feature in the pathophysiology of PCOS, precipitating ovulatory anomalies and endometrial dysfunctions that contribute to the infertility challenges characteristic of this condition. Despite it...

    Authors: Xi Luo, Yunhua Dong, Haishan Zheng, Xiaoting Zhou, Lujuan Rong, Xiaoping Liu, Yun Bai, Yunxiu Li and Ze Wu
    Citation: Journal of Ovarian Research 2024 17:79
  8. This study investigated the association between Anti-Müllerian Hormone (AMH) and relevant metabolic parameters and assessed its predictive value in the clinical diagnosis of polycystic ovarian syndrome (PCOS).

    Authors: Li Wang, Mengjun Luo, Xiaoyu Yu, Rong Li, Fei Ye, Dongsheng Xiong, Yan Gong, Mingyue Zheng, Weixin Liu and Jiuzhi Zeng
    Citation: Journal of Ovarian Research 2024 17:78
  9. Our explorative study assessed a panel of molecules for their association with epithelial ovarian carcinomas and their prognostic implications. The panel included tissue expression of VEGF-C, COX-2, Ki-67 and ...

    Authors: J. Bhaskari, Rahul Bhagat, V. Shilpa, C.S. Premalata and Lakshmi Krishnamoorthy
    Citation: Journal of Ovarian Research 2024 17:77
  10. Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women that necessitates effective and safe treatment alternatives. This study aimed to evaluate the therapeutic efficacy of Vitex negundo seed i...

    Authors: Tarun Kumar Kar, Sananda Sil, Angshita Ghosh, Ananya Barman and Sandip Chattopadhyay
    Citation: Journal of Ovarian Research 2024 17:76
  11. Umbilical cord-derived mesenchymal stem cell (UCMSC) transplantation has been deeply explored for premature ovarian insufficiency (POI) disease. However, the associated mechanism remains to be researched. To e...

    Authors: Na Yin, Chao Luo, Lun Wei, Guangzhao Yang, Le Bo and Caiping Mao
    Citation: Journal of Ovarian Research 2024 17:75
  12. Ovarian cancer is a leading cause of death among gynecologic tumors, often detected at advanced stages. Metabolic reprogramming and increased lipid biosynthesis are key factors driving cancer cell growth. Stea...

    Authors: Juwon Lee, Suin Jang, Jihye Im, Youngjin Han, Soochi Kim, HyunA Jo, Wenyu Wang, Untack Cho, Se Ik Kim, Aeran Seol, Boyun Kim and Yong Sang Song
    Citation: Journal of Ovarian Research 2024 17:73
  13. Polycystic ovarian syndrome (PCOS) is the most common endocrine disease in women of childbearing age which is often associated with abnormal proliferation or apoptosis of granulosa cells (GCs). Studies proved ...

    Authors: Feilan Xuan, Ruiying Jin, Weimei Zhou, Yongju Ye, Yuefang Ren, Jiali Lu and Aixue Chen
    Citation: Journal of Ovarian Research 2024 17:72
  14. Ovarian cancer remains the deadliest of the gynecologic cancers in the United States. There have been limited advances in treatment strategies that have seen marked increases in overall survival. Thus, it is e...

    Authors: Linah Al-Alem, Jillian M. Prendergast, Justin Clark, Bianca Zarrella, Dominique T. Zarrella, Sarah J. Hill, Whitfield B. Growdon, Venkatesh Pooladanda, David R. Spriggs, Daniel Cramer, Kevin M. Elias, Rawan I. Nazer, Steven J. Skates, Jeff Behrens, Daniel T. Dransfield and Bo R. Rueda
    Citation: Journal of Ovarian Research 2024 17:71
  15. Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic condition in women of childbearing age and a major cause of anovulatory infertility. The pathophysiology of PCOS is complex. Recent studi...

    Authors: Ping Zhou, Penghui Feng, Baoying Liao, Lin Fu, Hongying Shan, Canhui Cao, Renxin Luo, Tianliu Peng, Fenting Liu and Rong Li
    Citation: Journal of Ovarian Research 2024 17:69
  16. The gene cell division cycle associated 5 (CDCA5), also called sororin, has oncogenic characteristics and is upregulated in various carcinomas. Nevertheless, the involvement of CDCA5 in ovarian cancer (OC), a ...

    Authors: Qingsong Zhang, Rong Zhang, Yuzhi Li and Xiaojun Yang
    Citation: Journal of Ovarian Research 2024 17:68
  17. Premature ovarian insufficiency (POI) is a severe disorder leading to female infertility. Genetic mutations are important factors causing POI. TP63-truncating mutation has been reported to cause POI by increas...

    Authors: Yali Fan, Shuya Chen, Chunfang Chu, Xiaodan Yin, Jing Jin, Lingyan Zhang, Huihui Yan, Zheng Cao, Ruixia Liu, Mingwei Xin, Lin Li and Chenghong Yin
    Citation: Journal of Ovarian Research 2024 17:67
  18. Quiescin sulfhydryl oxidase 2 (QSOX2) is a flavin adenine dinucleotide-dependent sulfhydryl oxidase that is known to be involved in protein folding, cell growth regulation, and redox state modification through...

    Authors: Shih-Yun Chen, Tse-En Wang, Wei-Yun Lee, Ya-Yi Yang, Hong-Chun Lai, Fuko Matsuda, Haruhiko Kosek, You-Tzung Chen, Sheng-Hsiang Li and Pei-Shiue Tsai
    Citation: Journal of Ovarian Research 2024 17:66
  19. It is well described that circulating progesterone (P4) plays a key role in several reproductive events such as oocyte maturation. However, during diestrus, when circulating P4 is at the highest concentrations...

    Authors: Paola Maria da Silva Rosa, Alessandra Bridi, Giuliana de Ávila Ferronato, Cibele Maria Prado, Natália Marins Bastos, Juliano Rodrigues Sangalli, Flávio Vieira Meirelles, Felipe Perecin and Juliano Coelho da Silveira
    Citation: Journal of Ovarian Research 2024 17:65
  20. Ovarian cancer (OC) is a severe gynecological malignancy with significant diagnostic and therapeutic challenges. The discovery of reliable cancer biomarkers can be used to adjust diagnosis and improve patient ...

    Authors: Shihao Hong, Ni Fu, Shanliang Sang, Xudong Ma, Fangying Sun and Xiao Zhang
    Citation: Journal of Ovarian Research 2024 17:64
  21. Artificial Intelligence entails the application of computer algorithms to the huge and heterogeneous amount of morphodynamic data produced by Time-Lapse Technology. In this context, Machine Learning (ML) metho...

    Authors: S. Canosa, N. Licheri, L. Bergandi, G. Gennarelli, C. Paschero, M. Beccuti, D. Cimadomo, G. Coticchio, L. Rienzi, C. Benedetto, F. Cordero and A. Revelli
    Citation: Journal of Ovarian Research 2024 17:63
  22. Premature ovarian failure (POF) is a devastating condition for women under 40 years old. Chemotherapy, especially the use of cisplatin, has been demonstrated to promote the apoptosis of granulosa cells in prim...

    Authors: Rongli Wang, Feiyan Cheng and Xinyuan Yang
    Citation: Journal of Ovarian Research 2024 17:62
  23. Lymph node metastasis (LNM) is a major factor contributing to the high mortality rate of ovarian cancer, making the treatment of this disease challenging. However, the molecular mechanism underlying LNM in ova...

    Authors: Jiajia Li, Yihua Sun, Xiuling Zhi, Yating Sun, Zulimire Abudousalamu, Qianhan Lin, Bin Li, Liangqing Yao and Mo Chen
    Citation: Journal of Ovarian Research 2024 17:61
  24. Follitropin delta is a novel recombinant follicle stimulating hormone preparation uniquely expressed in a human fetal retinal cell line by recombinant DNA technology. To date, no systematic review was availabl...

    Authors: Stefano Palomba, Donatella Caserta, Paolo Emanuele Levi-Setti and Andrea Busnelli
    Citation: Journal of Ovarian Research 2024 17:60
  25. To investigate the clinical and magnetic resonance imaging (MRI) features for preoperatively discriminating  primary ovarian mucinous malignant tumors (POMTs) and metastatic mucinous carcinomas involving the o...

    Authors: Song-Qi Cai, Min-Rong Wu, Xiao-Liang Ma, Jing-Jing Lu, Jin-Wei Qiang, Yin-Yin Guan, Meng-Su Zeng and Jian-Jun Zhou
    Citation: Journal of Ovarian Research 2024 17:59
  26. Tumors are highly heterogeneous, and within their parenchyma, a small population of tumor-stem cells possessing differentiation potential, high oncogenicity, and self-renewal capabilities exists. These cells a...

    Authors: Guangwei Wang, Xiaofei Liu, Yue You, Silei Chen, Xiaohan Chang and Qing Yang
    Citation: Journal of Ovarian Research 2024 17:58
  27. Mesonephric-like adenocarcinoma is a new class of rare subtypes of the female reproductive system. Its clinical symptoms are similar to other types of ovarian tumors. The diagnosis is based on pathological and...

    Authors: Yun Yang, Mengru Zhao, Qiuchen Jia, Huimin Tang, Tingwei Xing, Yang Li, Bin Tang, Lin Xu, Weiwei Wei, Hong Zheng, Ruxia Shi, Bairong Xia and Jiming Chen
    Citation: Journal of Ovarian Research 2024 17:57
  28. The efficacy of subsequent therapy after poly-ADP-ribose polymerase (PARP) inhibitor maintenance treatment has raised concerns. Retrospective studies show worse outcomes for platinum-based chemotherapy after p...

    Authors: Nan Zhang, Hong Zheng, Yunong Gao, Tong Shu, Hongguo Wang and Yan Cai
    Citation: Journal of Ovarian Research 2024 17:55
  29. Oocytes of large animal species isolated from small ovarian follicles (< 2 mm) are less competent to support early embryonic development after in vitro maturation and fertilization than their counterparts isol...

    Authors: Alexandra Rosenbaum Bartková, Lucie Němcová, Veronika Kinterová, Dominika Radová, František Strejček, Tereza Toralová, Jozef Laurinčík and Radek Procházka
    Citation: Journal of Ovarian Research 2024 17:54
  30. Ovarian cancer is the eighth leading cause of cancer-related death among women, characterized by late diagnosis and a high relapse rate. In randomized controlled trials, we aimed to evaluate the efficacy and s...

    Authors: István Baradács, Brigitta Teutsch, Alex Váradi, Alexandra Bilá, Ádám Vincze, Péter Hegyi, Tamás Fazekas, Balázs Komoróczy, Péter Nyirády, Nándor Ács, Ferenc Bánhidy and Balázs Lintner
    Citation: Journal of Ovarian Research 2024 17:53
  31. Despite receiving first-line treatment, ovarian cancer patients continue to experience a high rate of recurrence; nearly all women with ovarian cancer develop chemoresistance and succumb to the disease. In thi...

    Authors: Biyao Jiang, Songshu Xiao, Shan Zhang and Fang Xiao
    Citation: Journal of Ovarian Research 2024 17:52
  32. Individual patients with ovarian cancer show remarkably different prognosis. Present prognostic models for ovarian cancer mainly focus on clinico-pathological parameters, so quantifiable prognostic markers at ...

    Authors: Hao Wang, Yin-hai Xu and Yi Guo
    Citation: Journal of Ovarian Research 2024 17:50
  33. Ovarian cancer is a significant challenge in women's health due to the lack of effective screening and diagnostic methods, often leading to late detection and the highest mortality rate among all gynecologic t...

    Authors: Ning Li, Xingmei Jiang, Qingyu Zhang, Yongmei Huang, Jinbin Wei, Haitao Zhang and Hui Luo
    Citation: Journal of Ovarian Research 2024 17:49
  34. Despite advances in medical imaging technology, the accurate preoperative prediction of lymph node status remains challenging in ovarian cancer. This retrospective study aimed to investigate the feasibility of...

    Authors: Yue Qi, Jinchi Liu, Xinyue Wang, Yuqing Zhang, Zhixun Li, Xinyu Qi and Ying Huang
    Citation: Journal of Ovarian Research 2024 17:48
  35. Evidence from the Istanbul consensus workshop suggests correlations between morphological parameters and embryo developments. 8-cell embryos are the best blastomere stage on day 3. No good quality evidence exi...

    Authors: Haijing Zhao, Keer Gan, Xiaohui Ji, Lingyan Zheng, Songbang Ou, Mei Mei, Qingxue Zhang, Hui Chen, Ping Yuan and Wenjun Wang
    Citation: Journal of Ovarian Research 2024 17:47
  36. Polycystic ovary syndrome (PCOS) is one of the most complex endocrine disorders in women of reproductive age. Abnormal proliferation of granulosa cells (GCs) is an important cause of PCOS. This study aimed to ...

    Authors: Jingyu Liu, Jie Li, Xin Wu, Mei Zhang, Guijun Yan, Haixiang Sun and Dong Li
    Citation: Journal of Ovarian Research 2024 17:44
  37. Polycystic ovary syndrome (PCOS) is a gynecological endocrine disease and could be considered a metabolic disease because it is often accompanied by obesity and insulin resistance. Brown adipose tissue (BAT) t...

    Authors: Yan Yan, Fangfang Di, Ruoxi Zhang, Liwen Song, Runjie Zhang and Jin Qiu
    Citation: Journal of Ovarian Research 2024 17:43
  38. To investigate the effects of metformin (MET) monotherapy and pioglitazone plus MET (PIOMET) therapy on gonadal and metabolic profiles in normal-weight women with polycystic ovary syndrome (PCOS).

    Authors: Han Zhao, Jiaqi Zhang, Chuan Xing, Xiangyi Cheng and Bing He
    Citation: Journal of Ovarian Research 2024 17:42
  39. Mucin 16 (MUC16) overexpression is linked with cancer progression, metastasis, and therapy resistance in high grade serous ovarian cancer and other malignancies. The cleavage of MUC16 forms independent bimodul...

    Authors: Kwangkook Lee, Kay Perry, Mengyao Xu, Irva Veillard, Raj Kumar, Thapi Dharma Rao, Bo R Rueda, David R Spriggs and Oladapo O Yeku
    Citation: Journal of Ovarian Research 2024 17:41
  40. Poor ovarian response (POR) is a big challenge for in vitro fertilization. The traditional Chinese medicine, Cai’s Prescription of Tonifying Kidney and Strengthening Vitals (Cai’s Prescription) has yielded sat...

    Authors: Zheng Wang, Denghao Liu, Yonghong Nie and Qinhua Zhang
    Citation: Journal of Ovarian Research 2024 17:40
  41. PCOS is a widespread disease that primarily caused in-pregnancy in pregnant-age women. Normoandrogen (NA) and Hyperandrogen (HA) PCOS are distinct subtypes of PCOS, while bio-markers and expression patterns fo...

    Authors: Wensu Liu, Tianyu Tang, Jianwei Feng, Chunyu Wang, Lin Lin, Shengli Wang, Kai Zeng, Renlong Zou, Zeyu Yang and Yue Zhao
    Citation: Journal of Ovarian Research 2024 17:38

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