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  1. The intricate interplay of gene expression within ovarian granulosa cells (GCs) is not fully understood. This study aimed to investigate the miRNA regulatory mechanisms of ferroptosis during the process of fol...

    Authors: Gulimire Abudureyimu, Yangsheng Wu, Ying Chen, Liqin Wang, Geng Hao, Jianguo Yu, Jianguo Wang, Jiapeng Lin and Juncheng Huang
    Citation: Journal of Ovarian Research 2024 17:3
  2. An unexpected impaired ovarian response pertains to an insufficient reaction to controlled ovarian hyperstimulation. This deficient reaction is identified by a reduced count of mature follicles and retrieved o...

    Authors: Gürkan Uncu, Kiper Aslan, Cihan Cakir, Berrin Avci, Isil Kasapoglu and Carlo Alviggi
    Citation: Journal of Ovarian Research 2024 17:1
  3. Epithelial ovarian cancer (OC) is the fourth leading cause of cancer-related deaths in women, with a 5-year survival rate of 30%-50%. Platinum resistance is the chief culprit for the high recurrence and mortal...

    Authors: Mengjun Zhang, Jialin Wang, Yan Guo, Haodi Yue and Lindong Zhang
    Citation: Journal of Ovarian Research 2023 16:240
  4. Polycystic ovary syndrome (PCOS) is a widespread heterogeneous disease that is in association with genetic, epigenetic, endocrine and environmental factors. Adipose-derived mesenchymal stem cell (ASC) and ASC-...

    Authors: Golnaz Shafiei, Mona Saheli, Sepideh Ganjalikhan-hakemi, Tahereh Haghpanah and Seyed Noureddin Nematollahi-mahani
    Citation: Journal of Ovarian Research 2023 16:238
  5. As a novel prognostic and inflammatory marker, the systemic immune-inflammation index (SII) has come to the foreground in recent years. SII may be used as an indicator reflecting the progressive inflammatory p...

    Authors: Xin Li, Ting Luan, Yi Wei, Juan Zhang, JuanJuan Zhang, Chun Zhao and Xiufeng Ling
    Citation: Journal of Ovarian Research 2023 16:236
  6. To investigate the efficacy of fertility-preserving treatment for young women with synchronous primary neoplasm of endometrium and ovary.

    Authors: Qujia Gama, Shuhan Luo, Pengfei Wu, Lulu Wang, Sijia Liu, Hongwei Zhang, Li Sun, Yiqin Wang, Min Yu, Xiaojun Chen, Weiwei Shan and Xuezhen Luo
    Citation: Journal of Ovarian Research 2023 16:235
  7. The ovary is an important reproductive organ in mammals, and its development directly affects the sexual maturity and reproductive capacity of individuals. MicroRNAs (miRNAs) are recognized as regulators of re...

    Authors: Yanyan Wang, Jianmin Wang, Qing Li, Rong Xuan, Yanfei Guo, Peipei He and Tianle Chao
    Citation: Journal of Ovarian Research 2023 16:234
  8. Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as a tumor suppressor i...

    Authors: Yi Zhang, Roslyn Tedja, Michael Millman, Terrence Wong, Alexandra Fox, Hussein Chehade, Meyer Gershater, Nicholas Adzibolosu, Radhika Gogoi, Matthew Anderson, Thomas Rutherford, Zhenggang Zhang, Michael Chopp, Gil Mor and Ayesha B. Alvero
    Citation: Journal of Ovarian Research 2023 16:233
  9. The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression. Exosomes, extracellular vesicles containing proteins involved in cell-cell co...

    Authors: Germano Aguiar Ferreira, Carolina Hassibe Thomé, Clarice Izumi, Mariana Lopes Grassi, Guilherme Pauperio Lanfredi, Marcus Smolka, Vitor Marcel Faça and Francisco José Candido dos Reis
    Citation: Journal of Ovarian Research 2023 16:232
  10. Clinical trials are currently exploring combinations of PARP inhibitors and immunotherapies for the treatment of ovarian cancer, but their effects on the ovarian tumour microenvironment (TME) remain unclear. H...

    Authors: Salar Farokhi Boroujeni, Galaxia Rodriguez, Kristianne Galpin, Edward Yakubovich, Humaira Murshed, Dalia Ibrahim, Sara Asif and Barbara C. Vanderhyden
    Citation: Journal of Ovarian Research 2023 16:231
  11. Clinical prediction models play an important role in the field of medicine. These can help predict the probability of an individual suffering from disease, complications, and treatment outcomes by applying spe...

    Authors: Guan Guixue, Pu Yifu, Gao Yuan, Liu Xialei, Shi Fan, Sun Qian, Xu Jinjin, Zhang Linna, Zhang Xiaozuo, Feng Wen and Yang Wen
    Citation: Journal of Ovarian Research 2023 16:230
  12. Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is generally considered as a pro-inflammatory cytokine which mediates anti-tumor immune response...

    Authors: Hui Zheng, Xiaolin Guan, Xin Meng, Ying Tong, Yanchun Wang, Suhong Xie, Lin Guo and Renquan Lu
    Citation: Journal of Ovarian Research 2023 16:229
  13. The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to the complex inheritance patterns and the highly heterogeneous phenotypes. This study aims ...

    Authors: Tingwenyi Hu, Chong Li, Sen Qiao, Weiwei Liu, Wei Han, Wei Li, Rong Shi, Xia Xue, Juanzi Shi, Guoning Huang and Tingting Lin
    Citation: Journal of Ovarian Research 2023 16:228
  14. Existing studies have investigated the relationship between the levels of serum inhibin B (INHB), anti-müllerian hormone (AMH) and precocious puberty in girls, but the results are inconsistent.

    Authors: Mei Jiang, Ying Gao, Tiange Qu, Yuechen Ji, Yiwen Niu, Jiaxin Zhang and Ling Huang
    Citation: Journal of Ovarian Research 2023 16:227
  15. The rescue in vitro mature(Rescue IVM) technique allows the use of immature oocytes collected in conventional COH to obtain more mature oocytes for fertilization through in vitro maturation. Some studies have ...

    Authors: Jianbo Wei, Zhongyu Luo, Xiyuan Dong, Huizi Jin, Lixia Zhu and Jihui Ai
    Citation: Journal of Ovarian Research 2023 16:226
  16. The oocyte and its surrounding cumulus cells (CCs) exist as an inseparable entity. The maturation of the oocyte relies on communication between the oocyte and the surrounding CCs. However, oocyte evaluation is...

    Authors: Yena Hu, Ran Zhang, Shuoping Zhang, Yaxing Ji, Qinwei Zhou, Lizhi Leng, Fei Meng, Fei Gong, Guangxiu Lu, Ge Lin and Liang Hu
    Citation: Journal of Ovarian Research 2023 16:225
  17. The influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on assisted reproductive technology (ART) has received increasing attention. It has been reported that the SARS-CoV-2 Rib...

    Authors: Yuling Mao, Yachao Yao, Hongzi Du, Zheng Wang, Xueliang Zhou, Ming Zeng, Chunyan Wang, Hanyan Liu, Yang Luo, Honghai Hong, Jianqiao Liu and Lei Li
    Citation: Journal of Ovarian Research 2023 16:224
  18. Ovarian cancer is a significant public health concern with a poor prognosis for epithelial ovarian cancer. To explore the potential of immunotherapy in treating epithelial ovarian cancer, we investigated the i...

    Authors: Hua Yang, Xiangyu Gu, Rong Fan, Qun Zhu, Sen Zhong, Xirun Wan, Qian Chen, Lan Zhu and Fengzhi Feng
    Citation: Journal of Ovarian Research 2023 16:223
  19. The objective of this study is to investigate the effects of an ethanolic extract derived from Agaricus subrufescens on rat models exhibiting Polycystic Ovarian Syndrome (PCOS) induced by Letrozole.

    Authors: Sarad Pawar Naik Bukke, Bharghava Bhushan Rao Pathange, Srikanth Kumar Karumanchi, Jalaiah Marri, Revathi Boyina, Kavya Rachamsetty, Bhargavi Manchikalapati, Saidi Odoma and Bello Hussaini
    Citation: Journal of Ovarian Research 2023 16:221
  20. High-grade serous ovarian cancer (OvCa) is the most common type of epithelial OvCa. It is usually diagnosed in advanced stages, leaving a woman’s chance of survival below 50%. Despite traditional chemotherapeu...

    Authors: Melayshia McFadden, Santosh Kumar Singh, Briana Kinnel, Sooryanarayana Varambally and Rajesh Singh
    Citation: Journal of Ovarian Research 2023 16:220
  21. Angiogenesis and metastasis contributes substantially to the poor outcome of patients with ovarian cancer. We aimed to explore the role and mechanisms of the long non-coding RNA NEAT1 (nuclear enriched abundan...

    Authors: Yang Liu, Yan Li, Yanzhi Wu, Yiyue Zhao, Xi Hu and Chunyi Sun
    Citation: Journal of Ovarian Research 2023 16:219
  22. High-grade serous carcinoma (HGSC) is the most common and aggressive subtype of epithelial ovarian cancer, characterized by gain-of-function TP53 mutations originating in the fallopian tube epithelium. Therapeuti...

    Authors: Madison Pereira, Alice Glogova, Jacob Haagsma, Julia Stewart, Trevor G. Shepherd and Jim Petrik
    Citation: Journal of Ovarian Research 2023 16:218
  23. Authors: Xing‑Hua Pan, Xue‑Juan Zhang, Xiang Yao, Ni‑Ni Tian, Zai‑Ling Yang, Kai Wang, Xiang‑Qing Zhu, Jing Zhao, Jie He, Xue‑Min Cai, Rong‑Qing Pang and Guang‑Ping Ruan
    Citation: Journal of Ovarian Research 2023 16:217

    The original article was published in Journal of Ovarian Research 2021 14:133

  24. Women with polycystic ovary syndrome (PCOS) have higher intestinal mucosal permeability, leading to the lipopolysaccharide (LPS) leakage and endotoxemia. This, in turn, leads to oxidative stress (OS) and neuro...

    Authors: Negin Nikrad, Mahdieh Abbasalizad Farhangi, Fatemeh Pourteymour Fard Tabrizi, Maryam Vaezi, Ata Mahmoudpour and Mehran Mesgari-Abbasi
    Citation: Journal of Ovarian Research 2023 16:216
  25. Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts, high androgen levels, and irregular menstruation. The causality between PCOS and breast cancer (BC) has been widely dis...

    Authors: Runxiang Cao, Lanlan Chen, Yutong Liu, Xuyutian Wang, Ruolin Ma, Qian Zhao and Ye Du
    Citation: Journal of Ovarian Research 2023 16:215
  26. No residual disease (CC 0) following cytoreductive surgery is pivotal for the prognosis of women with advanced stage epithelial ovarian cancer (EOC). Improving CC 0 resection rates without increasing morbidity...

    Authors: Diederick de Jong, Amudha Thangavelu, Timothy Broadhead, Inga Chen, Dermot Burke, Richard Hutson, Racheal Johnson, Angelika Kaufmann, Peter Lodge, David Nugent, Aaron Quyn, Georgios Theophilou and Alexandros Laios
    Citation: Journal of Ovarian Research 2023 16:214
  27. The oocyte cumulus complex is mainly composed of an oocyte, the perivitelline space, zona pellucida and numerous granulosa cells. The cumulus granulosa cells (cGCs) provide a particularly important microenviro...

    Authors: Chongyi Shu, Yiqi Yu, Xiaopan Chen, Jiansheng Guo, Yier Zhou, Dandan Wu, Tianyun Yang, Yuhang Fan, Qiongxiao Huang and Jing Shu
    Citation: Journal of Ovarian Research 2023 16:213
  28. To study whether CAG repeat polymorphism of androgen receptor (AR) contributes to the risk of polycystic ovarian morphology (PCOM) with antral follicle count (AFC) ≥ 20 in the context of new international guideli...

    Authors: Xueqi Yan, Xueying Gao, Qian Shang, Ziyi Yang, Yuteng Wang, Li Liu, Wei Liu, Dan Liu, Fang Cheng, Shigang Zhao, Han Zhao, Junli Zhao and Zi-Jiang Chen
    Citation: Journal of Ovarian Research 2023 16:211
  29. Premature ovarian insufficiency (POI) is a highly heterogeneous disease, and up to 25% of the cases can be explained by genetic causes. G protein-coupled receptor 3 (GPR3) plays an important role in oocyte arr...

    Authors: Shuting Ren, Feng Zhang, Lingyue Shang, Xi Yang, Yuncheng Pan, Xiaojin Zhang and Yanhua Wu
    Citation: Journal of Ovarian Research 2023 16:210
  30. The therapeutic effect of poly (ADP-ribose) polymerase inhibitors (PARPi) monotherapy compared with platinum-based chemotherapy, and the impact to subsequent platinum-based chemotherapy after PARPi resistance ...

    Authors: Yana Ma, Jiale Liu, Ning Li, Hualei Bu, Yongwen Huang, Chengjuan Jin, Hao Wen, Shuai Feng, Hui Zhang, Xiaorong Yang, Beihua Kong, Lingying Wu and Kun Song
    Citation: Journal of Ovarian Research 2023 16:209
  31. Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Animal models have been developed and used as tools to unrave...

    Authors: Haowen Wu, Bining Zhao, Qiyang Yao and Jihong Kang
    Citation: Journal of Ovarian Research 2023 16:207
  32. Follicular microenvironment has been proposed as an important factor for oocyte grown and maturation. We sought to evaluate the oxidative stress and inflammatory levels in follicular fluid (FF) and association...

    Authors: Yan Huang, Yi Cheng, Min Zhang, Yan Xia, Xiaoyan Chen, Yexing Xian, Dewei Lin, Suyan Xie and Xinyu Guo
    Citation: Journal of Ovarian Research 2023 16:206
  33. The immune system played a multifaceted role in ovarian cancer (OC) and was a significant mediator of ovarian carcinogenesis. Various immune cells and immune gene products played an integrated role in ovarian ...

    Authors: Hongjun Fei, Xu Han, Yanlin Wang and Shuyuan Li
    Citation: Journal of Ovarian Research 2023 16:205
  34. Studies have shown that supplementation with recombinant human GH (rh-GH) during ovarian stimulation (OS) may improve the ovarian response and clinical outcomes of IVF. However, it remains unclear whether GH i...

    Authors: Yilun Sui, Min Xiao, Jing Fu, Lu Li, Yining Xu, Caixia Lei and Xiaoxi Sun
    Citation: Journal of Ovarian Research 2023 16:204
  35. Premature ovarian insufficiency (POI) is an important cause of infertility characterized by the functional decline of the ovary. Granulosa cells (GCs) around oocytes are critical for folliculogenesis, and GC d...

    Authors: Dan Liu, Xiaohong Guan, Wenqiang Liu, Yanping Jia, Hong Zhou, Chenxiang Xi, Mei Zhao, Yuan Fang, Li Wu and Kunming Li
    Citation: Journal of Ovarian Research 2023 16:203
  36. Gynecologic cancers comprise malignancies in the female reproductive organs. Ovarian cancer ranks sixth in terms of incidence rates while seventh in terms of mortality rates. The stage at which ovarian cancer ...

    Authors: Khushbukhat Khan, Sameen Zafar, Yasmin Badshah, Naeem Mahmood Ashraf, Mehak Rafiq, Lubna Danish, Maria Shabbir, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal and Suhail Razak
    Citation: Journal of Ovarian Research 2023 16:202
  37. The factors affecting the cumulative live birth rate (CLBR) of PCOS (Polycystic ovary syndrom) patients who received in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) needs ...

    Authors: You Li, Leizhen Xia, Zengming Li, Ziyu Zhang and Ru Jiang
    Citation: Journal of Ovarian Research 2023 16:201
  38. Patients with epithelial ovarian carcinoma (EOC) are usually diagnosed at an advanced stage with tumour cell invasion. However, identifying the underlying molecular mechanisms and biomarkers of EOC proliferati...

    Authors: Yuanfu Zhang, Shu Sun, Yue Qi, Yifan Dai, Yangyang Hao, Mengyu Xin, Rongji Xu, Hongyan Chen, Xiaoting Wu, Qian Liu, Congcong Kong, Guangmei Zhang, Peng Wang and Qiuyan Guo
    Citation: Journal of Ovarian Research 2023 16:200
  39. Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life. Previous studies have demonstrated that ...

    Authors: Wenjie Dai, Hong Yang, Bo Xu, Tiantian He, Ling Liu, Xiaoqian Ma, Jiaxue Ma, Guoqin Yang, Rui Si, Xiuying Pei, Xing Du and Xufeng Fu
    Citation: Journal of Ovarian Research 2023 16:198
  40. Whether pretreatment with gonadotropin-releasing hormone agonist (GnRHa) can improve the pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles is controversial. The inconsistencies in the results of...

    Authors: Bin Xu, Zhaojuan Hou, Nenghui Liu, Jing Zhao and Yanping Li
    Citation: Journal of Ovarian Research 2023 16:197
  41. Ovarian cancer (OV) is the most fatal gynecological malignant tumor worldwide, with high recurrence rates and great heterogeneity. Pyroptosis is a newly-acknowledged inflammatory form of cell death with an ess...

    Authors: Jiani Yang, Chao Wang, Yue Zhang, Shanshan Cheng, Yanna Xu and Yu Wang
    Citation: Journal of Ovarian Research 2023 16:196
  42. Natural cycle- in vitro fertilization (NC-IVF) is particularly recommended for women with decreased ovarian reserve (DOR) or poor response to controlled ovarian hyperstimulation. In these cases, it can be chal...

    Authors: Tian Tian, Yu Li, Jiaxin Lv, Lixue Chen, Yuanyuan Wang, Rui Yang, Ping Liu, Rong Li and Jie Qiao
    Citation: Journal of Ovarian Research 2023 16:195
  43. The nuclear receptor subfamily 5 group A member 1 (NR5A1), encoding steroidogenic factor 1 (SF-1), has been identified as a critical factor in gonadal development in animal studies. A previous study of ours sugge...

    Authors: Laura Danti, Karolina Lundin, Kirsi Sepponen, Dawit A. Yohannes, Juha Kere, Timo Tuuri and Juha S. Tapanainen
    Citation: Journal of Ovarian Research 2023 16:194
  44. Evaluating the efficacy of letrozole overlapped with gonadotropin-modified letrozole protocol (mLP) for diminished ovarian reserve (DOR) or advanced-age women with repeated cycles.

    Authors: Xiaojia Li, Jingbo Chen, Yang Zhao, Fengyi He, Meijun Zeng, Guijun Guan and Xiaomiao Zhao
    Citation: Journal of Ovarian Research 2023 16:193

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