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  1. Long non-coding RNA PTPRG antisense RNA 1 (PTPRG-AS1) deregulation has been reported in various human malignancies and identified as an important modulator of cancer development. Few reports have focused on th...

    Authors: Juanjuan Shi, Xijian Xu, Dan Zhang, Jiuyan Zhang, Hui Yang, Chang Li, Rui Li, Xuan Wei, Wenqing Luan and Peishu Liu

    Citation: Journal of Ovarian Research 2020 13:127

    Content type: Research

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  2. This study aimed to explore the effects of activating GABAB1 receptor by baclofen on proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of ovarian cancer cells.

    Authors: Jun Gao, Yao Gao, Shixin Lin, Xia Zou, Yukai Zhu, Xintong Chen, Hong Wan and Hong Zhu

    Citation: Journal of Ovarian Research 2020 13:126

    Content type: Research

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  3. High-grade serous ovarian cancer (HGSOC) is the most common and lethal subtype of ovarian cancer. A growing body of evidence suggests tumor-supporting roles of several members of the kallikrein-related peptida...

    Authors: Weiwei Gong, Yueyang Liu, Eleftherios P. Diamandis, Marion Kiechle, Holger Bronger, Julia Dorn, Tobias Dreyer and Viktor Magdolen

    Citation: Journal of Ovarian Research 2020 13:125

    Content type: Research

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  4. Ovarian cancer is the eighth most commonly occurring cancer in women. Clinically, the limitation of conventional screening and monitoring approaches inhibits high throughput analysis of the tumor molecular mar...

    Authors: Mina Sharbatoghli, Somayeh Vafaei, Hamidreza Aboulkheyr Es, Mohsen Asadi-Lari, Mehdi Totonchi and Zahra Madjd

    Citation: Journal of Ovarian Research 2020 13:124

    Content type: Review

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  5. Ovarian clear cell carcinoma (OCCC) is a rare histologic type of ovarian cancer. There is a lack of an efficient prognostic predictive tool for OCCC in clinical work. This study aimed to construct and validate...

    Authors: Qian Chen, Shu Wang and Jing-He Lang

    Citation: Journal of Ovarian Research 2020 13:123

    Content type: Research

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  6. MicroRNAs (MiRNAs) is thought to play a critical role in the initiation and progress of ovarian cancer (OC). Although miRNAs has been widely recognized in ovarian cancer, the role of hsa-miR-30a-5p (miR-30a) in.....

    Authors: Weijia Lu, Yunyu Wu, Can Xiong Lu, Ting Zhu, Zhong Lu Ren and Zhiwu Yu

    Citation: Journal of Ovarian Research 2020 13:120

    Content type: Research

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  7. Wilms tumor 1 associated protein (WTAP) modulates other genes via transcriptional and post-transcriptional regulation, in particular, by acting as a N6-methyladenosine writer or binding to the 3’UTR of mRNA, a...

    Authors: Jing Wang, Jing Xu, Ke Li, Yunke Huang, Yilin Dai, Congjian Xu and Yu Kang

    Citation: Journal of Ovarian Research 2020 13:119

    Content type: Research

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  8. The second major cause of death is cancer. In fact, the effectiveness of anticancer treatments and positive long-term prognosis for young women has increased. However, the problem of post-cancer infertility pl...

    Authors: Vladimir Isachenko, Bernd Morgenstern, Plamen Todorov, Evgenia Isachenko, Peter Mallmann, Bettina Hanstein and Gohar Rahimi

    Citation: Journal of Ovarian Research 2020 13:118

    Content type: Case report

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  9. The foundation of modern ovarian cancer care is cytoreductive surgery to remove all macroscopic disease (R0). Identification of R0 resection patients may help individualise treatment. Machine learning and AI h...

    Authors: Alexandros Laios, Alexandros Gryparis, Diederick DeJong, Richard Hutson, Georgios Theophilou and Chris Leach

    Citation: Journal of Ovarian Research 2020 13:117

    Content type: Research

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  10. Ovarian cancer is the second fatal malignancy of the female reproductive system. Based on the cancer stem cell (CSC) theory, its poor prognosis of ovarian cancer attributed to tumor recurrence caused by CSCs. ...

    Authors: Xiaoxiao Zhang, Yue Su, Xue Wu, Rourou Xiao, Yifan Wu, Bin Yang, Zhen Wang, Lili Guo, Xiaoyan Kang and Changyu Wang

    Citation: Journal of Ovarian Research 2020 13:116

    Content type: Research

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  11. The loss of ovarian function in women, referred to as premature ovarian insufficiency (POI), is associated with a series of concomitant diseases. POI is genetically heterogeneous, and in most cases, the etiolo...

    Authors: Hongli Liu, Xiaoli Wei, Yanwei Sha, Wensheng Liu, Haijie Gao, Jin Lin, Youzhu Li, Yaling Tang, Yifeng Wang, Yanlong Wang and Zhiying Su

    Citation: Journal of Ovarian Research 2020 13:114

    Content type: Research

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  12. To assess the anti-tumor activity and side effects of different dosages of paclitaxel (albumin binding type) (hereinafter referred to as nab-P) combined with Apatinib (hereinafter referred to as AP) in platinu...

    Authors: Hong Zhao, Rong Li, Xiaoyan Wang, Xin Lu, Min Hu, Jinbin Zhang, Xia Zhao, Xiaoqin Song and Yangyang Liu

    Citation: Journal of Ovarian Research 2020 13:113

    Content type: Research

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  13. In this study we aimed to identify a prognostic signature in BRCA1/2 mutations to predict disease progression and the efficiency of chemotherapy ovarian cancer (OV), the second most common cause of death from gyn...

    Authors: Yinglian Pan, Li Ping Jia, Yuzhu Liu, Yiyu Han, Qian Li, Qin Zou, Zhongpei Zhang, Jin Huang and Qingchun Deng

    Citation: Journal of Ovarian Research 2020 13:112

    Content type: Research

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  14. RNA methylation can reverse the methylation modification at the RNA level, which is an extremely important epigenetic modification. The function and mechanism of YTHDF2, as a reader of m6A modification, in epi...

    Authors: Jie Li, Lei Wu, Meili Pei and Yun Zhang

    Citation: Journal of Ovarian Research 2020 13:111

    Content type: Research

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  15. Ovarian cancer (OC) has been regarded as the most malignant gynecological neoplasm and often confers grave outcomes owing to the frequent metastasis and high recurrence. A previous study has demonstrated that ...

    Authors: Feng-Juan Han, Jia Li, Ying Shen, Ying Guo, Yi-Chao Liu, Yang Yu, Jia-Yue Xu, Shao-Xuan Liu and Yan-Hong Wang

    Citation: Journal of Ovarian Research 2020 13:110

    Content type: Research

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  16. The presence of Degenerated Oocyte (DEG) was mostly described after intracytoplasmic sperm injection (ICSI), with fewer reports on DEG at the time of ovum pick-up (OPU). This study aims to assess morphokinetic...

    Authors: Yuval Atzmon, Mediea Michaeli, Diana Poltov, Nechami Rotfarb, Oshrit Lebovitz, Nardin Aslih and Einat Shalom-Paz

    Citation: Journal of Ovarian Research 2020 13:109

    Content type: Research

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  17. The aim of this study was to investigate the effect of bioactive peptides (BAPT) from animal sources on the development of mouse preantral follicles in vitro. Preantral follicles were isolated and randomly div...

    Authors: Gang Liu, Shubin Li, Jinyu Ren, Chunyu Wang, Yaxuan Zhang, Xiulan Su and Yanfeng Dai

    Citation: Journal of Ovarian Research 2020 13:108

    Content type: Research

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  18. The exact pathogenesis of polycystic ovary syndrome (PCOS), the most common neuroendocrine disorder in women of reproductive age, has not been fully elucidated. Recent studies suggested that chronic inflammati...

    Authors: Zixuan Gao, Xiaochen Ma, Jing Liu, Yuhang Ge, Lei Wang, Ping Fu, Zhian Liu, Ruiqin Yao and Xiaonan Yan

    Citation: Journal of Ovarian Research 2020 13:106

    Content type: Research

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  19. The number of cases of novel coronavirus disease 2019 (COVID-19) in Japan have risen since the first case was reported on January 24, 2020, and 6225 infections have been reported as of June 30, 2020. On April ...

    Authors: Yuya Nogami, Yusuke Kobayashi, Kosuke Tsuji, Megumi Yokota, Hiroshi Nishio, Masaru Nakamura, Wataru Yamagami, Tohru Morisada, Eiichiro Tominaga, Kouji Banno and Daisuke Aoki

    Citation: Journal of Ovarian Research 2020 13:105

    Content type: Case report

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  20. Circular RNAs (circRNAs) are a newly discovered class of endogenous non-coding RNAs that play an important role in growth and development by regulating gene expression and participating in a variety of biologi...

    Authors: Su Xie, Mengxun Li, Yansen Chen, Yi Liu, Lipeng Ma, Xiaomei Sun, Yishan Sun, Ruonan Gao and Tao Huang

    Citation: Journal of Ovarian Research 2020 13:104

    Content type: Research

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  21. In clinical practice alterations in CA-125 concentration within normal range in patients with ovarian cancer after first-line treatment are common. Even minor increase in CA-125 concentration is associated wit...

    Authors: Szymon Piatek, Grzegorz Panek, Zbigniew Lewandowski, Mariusz Bidzinski, Dominika Piatek, Przemyslaw Kosinski and Miroslaw Wielgos

    Citation: Journal of Ovarian Research 2020 13:102

    Content type: Research

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  22. Detailed epidemiologic descriptions of large populations of advanced stage ovarian cancer patients have been lacking to date. This study aimed to describe the patient characteristics, treatment patterns, survi...

    Authors: Daniel C. Beachler, Francois-Xavier Lamy, Leo Russo, Devon H. Taylor, Jade Dinh, Ruihua Yin, Aziza Jamal-Allial, Samuel Dychter, Stephan Lanes and Patrice Verpillat

    Citation: Journal of Ovarian Research 2020 13:101

    Content type: Research

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  23. Ovarian cancer typically is diagnosed late because insensitivity and lack of specificity of current biomarkers prior to its clinical detection. Ribosomal protein S6 (RPS6) is a ribosomal protein involved in th...

    Authors: Xueqing Yang, Luxi Xu, Yu-e Yang, Chang Xiong, Jinjin Yu, Yuan Wang and Yaying Lin

    Citation: Journal of Ovarian Research 2020 13:100

    Content type: Research

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  24. Ovarian cancer is the second most common gynecologic cancer with high mortality rate and generally diagnosed in advanced stages. The 5-year disease-free survival is below 40%. MicroRNAs, subset of the non-codi...

    Authors: Seref Bugra Tuncer, Ozge Sukruoglu Erdogan, Seda Kilic Erciyas, Mukaddes Avsar Saral, Betul Celik, Demet Akdeniz Odemis, Gozde Kuru Turkcan and Hulya Yazici

    Citation: Journal of Ovarian Research 2020 13:99

    Content type: Research

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  25. Intercellular exchange between the oocyte and its surrounding cells within the follicular environment is critical for oocyte maturation and subsequent development. In vertebrates this exchange is facilitated t...

    Authors: Zachary Timothy Dye, Lauren Virginia Rutledge, Silvia Penuela and Paul William Dyce

    Citation: Journal of Ovarian Research 2020 13:98

    Content type: Research

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  26. In the context of a continuously increased delay of motherhood and of an increase of the incidence of premature ovarian failure, it is of the greatest interest to dispose of a predictive marker of the duration...

    Authors: Anne-Julie Fattet, Simon Toupance, Simon N. Thornton, Nicolas Monnin, Jean-Louis Guéant, Athanase Benetos and Isabelle Koscinski

    Citation: Journal of Ovarian Research 2020 13:96

    Content type: Review

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  27. Ovarian cancer is the leading cause of cancer-related death among women. Complete cytoreductive surgery followed by platinum-taxene chemotherapy has been the gold standard for a long time. Various compounds ha...

    Authors: Kuo-Chang Wen, Pi-Lin Sung, Alexander T. H. Wu, Ping-Chieh Chou, Jun-Hung Lin, Chi-Ying F. Huang, Sai-Ching J. Yeung and Mong-Hong Lee

    Citation: Journal of Ovarian Research 2020 13:95

    Content type: Research

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  28. To determine if a modified ovarian sensitivity index (MOSI), based on initial follicular measurements and the initial follicle-stimulating hormone (FSH) dose, can predict the production of high-quality embryos...

    Authors: David Camargo-Mattos, Uziel García, Felipe Camargo-Diaz, Ginna Ortiz, Ivan Madrazo and Esther Lopez-Bayghen

    Citation: Journal of Ovarian Research 2020 13:94

    Content type: Research

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  29. Cumulus cells (CC) encapsulate growing oocytes and support their growth and development. Transcriptomic signatures of CC have the potential to serve as valuable non-invasive biomarkers for oocyte competency an...

    Authors: Brandon A. Wyse, Noga Fuchs Weizman, Seth Kadish, Hanna Balakier, Mugundhine Sangaralingam and Clifford L. Librach

    Citation: Journal of Ovarian Research 2020 13:93

    Content type: Research

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  30. MicroRNAs (miRNAs) play crucial functions in the progression of ovarian cancer. MicroRNA-27b-5p (miR-27b-5p) has been identified as a cancer-associated miRNA. Nevertheless, the expression profile of miR-27b-5p...

    Authors: Chun Hua Liu, Xue Ning Jing, Xiao Lan Liu, Shan Yong Qin, Min Wei Liu and Chun Hong Hou

    Citation: Journal of Ovarian Research 2020 13:92

    Content type: Research

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  31. In order to investigate whether adjuvant chemotherapy is essential for patients with early-stage serous and endometrioid epithelial ovarian cancer, the present study collected data from the US Surveillance, Ep...

    Authors: Shuqing Li and Zhiling Zhu

    Citation: Journal of Ovarian Research 2020 13:91

    Content type: Research

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  32. MiRNAs play important roles in the development of ovarian cancer, activation of primitive follicles, follicular development, oocyte maturation and ovulation. In the present study, we investigated the specific ...

    Authors: Ji Lin, Huijuan Huang, Liheng Lin, Weiwei Li and Jianfen Huang

    Citation: Journal of Ovarian Research 2020 13:90

    Content type: Research

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  33. This study attempts to evaluate whether preoperative systemic inflammatory response (SIR) markers or other hematological variables, such as albumin, D-dimer, and carbohydrate antigen 125, play roles in predict...

    Authors: Wei Chen, Siyuan Zhong, Boer Shan, Shuling Zhou, Xiaohua Wu, Huijuan Yang and Shuang Ye

    Citation: Journal of Ovarian Research 2020 13:89

    Content type: Research

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  34. This study aims to determine the impact of assisted hatching (AH) on pregnancy outcomes in vitrified-warmed blastocyst transfers, and evaluate if embryo expansion or morphology influences outcomes.

    Authors: Charis Ng, Marta Wais, Taryn Nichols, Sarah Garrow, Julius Hreinsson, Zhong-Cheng Luo and Crystal Chan

    Citation: Journal of Ovarian Research 2020 13:88

    Content type: Research

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  35. Whether menstrual variability in women with regular and ovulatory cycle could affect embryo implantation remains controversial, with conflicting evidences presented in the literature. Thus, in this study, we e...

    Authors: Ying Ying, Fuman Qiu, Qing Huang, Sichen Li, Haiying Liu and Jianqiao Liu

    Citation: Journal of Ovarian Research 2020 13:87

    Content type: Research

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  36. The current study evaluated the metalloproteinases MMP-2 and MMP-9 expression in epithelial cells and the surrounding stroma in ovarian tumors and the association of MMPs with the histological subtypes, the cl...

    Authors: Flavia Morales-Vásquez, Rocío Castillo-Sánchez, María J. Gómora, Miguel Ángel Almaraz, Enrique Pedernera, Delia Pérez-Montiel, Elizabeth Rendón, Horacio Noé López-Basave, Edgar Román-Basaure, Sergio Cuevas-Covarrubias, Juan Maldonado-Cubas, Antonio Villa and Carmen Mendez

    Citation: Journal of Ovarian Research 2020 13:86

    Content type: Research

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  37. Wnt-inducible signaling pathway protein 2 (WISP2) is a wnt1-induced signaling pathway protein 2. Although studies indicate that WISP2 may promote the development of various tumors, its role in ovarian cancer r...

    Authors: Zi-Qing Shi, Zi-Yan Chen, Yao Han, Heng-Yan Zhu, Meng-Dan Lyu, Han Zhang, Yi Zhang, Liu-Qing Yang and Wei-Wei Pan

    Citation: Journal of Ovarian Research 2020 13:85

    Content type: Research

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  38. Ovarian cancer (OvCa) is one of the most lethal tumors of gynecologic malignancies, due to lack of early detection, and a high rate of metastasis. The standard treatment for OvCa is surgery and cytotoxic chemo...

    Authors: Caroline E. Ukwade, Osaretin A. T. Ebuehi, Rahmat A. Adisa, Santosh K. Singh and Rajesh Singh

    Citation: Journal of Ovarian Research 2020 13:83

    Content type: Research

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  39. Serous ovarian carcinomas (SCA) are the most common and most aggressive ovarian carcinoma subtype which etiology remains unclear. To investigate the prospective role of mRNAs in the tumorigenesis and progressi...

    Authors: Hongjun Fei, Songchang Chen and Chenming Xu

    Citation: Journal of Ovarian Research 2020 13:82

    Content type: Research

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  40. circular RNAs (circRNAs) have been reported to be essential regulators of multiple malignant cancers. However, the functions of circRNAs in ovarian cancer need to be further explored. The aim of our study is t...

    Authors: Qin Xu, Bo Deng, Manlin Li, Yang Chen and Li Zhuan

    Citation: Journal of Ovarian Research 2020 13:81

    Content type: Research

    Published on:

  41. Problems with fallopian tubes are one of the main reasons for women to undergo in vitro fertilization-embryo transfer (IVF-ET). A large proportion of women with ectopic pregnancy, fallopian tube obstruction an...

    Authors: Tong Chen, Feiyan Zhao, Qin Wang, Chang Liu, Yonglian Lan, Shuyu Wang, Zhimin Xin and Xiaokui Yang

    Citation: Journal of Ovarian Research 2020 13:80

    Content type: Research

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  42. We sought to determine the impact of pretreatment plasma platelet levels, dimerized plasmin fragment (D-dimer) and fibrinogen in recurrent epithelial ovarian cancer (EOC) and the impact of platelet levels on S...

    Authors: Qinghong Hu, Abha Hada and Liping Han

    Citation: Journal of Ovarian Research 2020 13:78

    Content type: Research

    Published on:

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