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  1. Ovarian cancer during pregnancy is relatively rare and treatment strategies are inexperienced in surgery and chemotherapy. Multidisciplinary management of advanced epithelial ovarian cancer in pregnant patient...

    Authors: Tianmin Xu, Liang Wang, Yan Jia, Zanhui Jia, Zhuo Li, Shaohai Cui and Manhua Cui

    Citation: Journal of Ovarian Research 2019 12:108

    Content type: Case report

    Published on:

  2. Cisplatin-based chemotherapy is the first-line treatment for ovarian cancer. However, acquired resistance to cisplatin treatment often occurs in epithelial ovarian cancer, and effective and practical methods f...

    Authors: Bo Zhou, Meng Xia, Bin Wang, Niresh Thapa, Lijuan Gan, Chaoyang Sun, Ensong Guo, Jia Huang, Yulan Lu and Hongbin Cai

    Citation: Journal of Ovarian Research 2019 12:107

    Content type: Research

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  3. Ovarian carcinoma (OC) is a common cause of death among women with gynecological cancer. MicroRNAs (miRNAs) are believed to have vital roles in tumorigenesis of OC. Although miRNAs are broadly recognized in OC...

    Authors: Yaowei Li and Li Li

    Citation: Journal of Ovarian Research 2019 12:106

    Content type: Research

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  4. Epithelial ovarian cancer (EOC) remains the most lethal gynecological cancer in developed countries, indicating the need for further research. Although current cancer models prove useful, they have major limit...

    Authors: Sander Dumont, Ziga Jan, Ruben Heremans, Toon Van Gorp, Ignace Vergote and Dirk Timmerman

    Citation: Journal of Ovarian Research 2019 12:105

    Content type: Review

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  5. Young girls before menarche or menstruating adolescent women may experience long-term drug-resistant chronic pelvic pain, as well as other symptoms associated with pelvic mass. In such cases, it is of great im...

    Authors: Krzysztof Gałczyński, Maciej Jóźwik, Dorota Lewkowicz, Anna Semczuk-Sikora and Andrzej Semczuk

    Citation: Journal of Ovarian Research 2019 12:104

    Content type: Review

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  6. Epithelial ovarian cancer (EOC) is usually diagnosed late at an advanced stage. Though EOC initially responds to treatment, the recurrence rate is pretty high. The efficacy of different targeted therapies redu...

    Authors: Sudeep Gupta, Shona Nag, Shyam Aggarwal, Amit Rauthan and Narayanankutty Warrier

    Citation: Journal of Ovarian Research 2019 12:103

    Content type: Review

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  7. Breast cancer is the most common cancer in young women. Fortunately current survival rates of BC are significant which makes future fertility very important for quality of life of BC survivors. Chemotherapy ca...

    Authors: Cristina Silva, Ana Cristina Ribeiro Rama, Sérgio Reis Soares, Mariana Moura-Ramos and Teresa Almeida-Santos

    Citation: Journal of Ovarian Research 2019 12:102

    Content type: Research

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  8. Ovarian carcinoma is a lethal gynecological malignancy. Women with ovarian cancer (OC) are highly recurrent and typically diagnosed at late stage. Ten-eleven translocation protein 3 (TET3) belongs to the famil...

    Authors: Tiefeng Cao, Wenwei Pan, Xiaoli Sun and Huimin Shen

    Citation: Journal of Ovarian Research 2019 12:101

    Content type: Review

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  9. Ovarian cancer is the most common gynecological malignancy that causes cancer-related deaths in women today; this being the case, developing an understanding of ovarian cancer has become one of the major drivi...

    Authors: Yingyu Dou, Xiaoyan Jiang, Hui Xie, Junyu He and Songshu Xiao

    Citation: Journal of Ovarian Research 2019 12:99

    Content type: Review

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  10. Endometriosis patients undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment suffer from lower success rates. The success of IVF-ET is related to the receptivity of the uterus and the quality of...

    Authors: Yu Liang, Xiaokui Yang, Yonglian Lan, Lingling Lei, Ying Li and Shuyu Wang

    Citation: Journal of Ovarian Research 2019 12:98

    Content type: Research

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  11. Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance. Intercellular adhesion molecule-1 (ICAM-1) is a proinflammatory ...

    Authors: Nearmeen M. Rashad, Amal S. El-Shal, Hala G. Abomandour, Amr Mostafa Kamel Aboelfath, Mohamed el sayed Rafeek, Mohammad Samir Badr, Ayman E. Ali, Mohammed S. Yousef, Maha Abdelhamid Fathy and Mustafa taha Abdelfattah Sharaf el din

    Citation: Journal of Ovarian Research 2019 12:97

    Content type: Research

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  12. Development of a hyper-gonadotropic hypoestrogenism condition in women < 40 years, defined as premature ovarian insufficiency (POI), is the most common long-term complication in female survivors of galactosemi...

    Authors: Marzieh Rostami Dovom, Mahsa Noroozzadeh, Nariman Mosaffa, Azita Zadeh–Vakili, Abbas Piryaei and Fahimeh Ramezani Tehrani

    Citation: Journal of Ovarian Research 2019 12:96

    Content type: Review

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  13. Large cell neuroendocrine carcinoma is a very rare ovarian neoplasm that has a poor clinical outcome even in the early stage, and there is as yet no established treatment. Diagnostic laparoscopy has been used ...

    Authors: Hideaki Tsuyoshi, Kenji Yashiro, Shizuka Yamada, Makoto Yamamoto, Toshimichi Onuma, Tetsuji Kurokawa and Yoshio Yoshida

    Citation: Journal of Ovarian Research 2019 12:95

    Content type: Case report

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  14. The polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder, clinically characterized by oligo-ovulation/chronic anovulation, menstrual irregularities, hyperandrogenism (such as hirsutism, acne),...

    Authors: Zeng-Hong Wu, Yun Tang, Xun Niu, Fei-Fei Pu, Xi-Yue Xiao and Wen Kong

    Citation: Journal of Ovarian Research 2019 12:94

    Content type: Review

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  15. The ST6Gal-I glycosyltransferase, which adds α2–6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer. Prior studies have shown that ST6Gal-I-med...

    Authors: Kaitlyn A. Dorsett, Robert B. Jones, Katherine E. Ankenbauer, Anita B. Hjelmeland and Susan L. Bellis

    Citation: Journal of Ovarian Research 2019 12:93

    Content type: Research

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  16. AB209371 gene has been characterized as an oncogenic lncRNA in liver cancer. However, its involvement in ovarian carcinoma (OC) is unknown. In the present study, we analyzed the roles of AB209371 in OC. We fou...

    Authors: Zi-Hui Zheng, Dong-Mei Wu, Shao-Hua Fan, Xin Wen, Xin-Rui Han, Shan Wang, Yong-Jian Wang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Yuan-Lin Zheng and Jun Lu

    Citation: Journal of Ovarian Research 2019 12:92

    Content type: Research

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  17. A retrospective case-control study was performed to evaluate whether PCOS-specific serum markers would change in women with polycystic ovary syndrome (PCOS) during the course of two consecutive cycles of clomi...

    Authors: Marlene Hager, Steffen Hörath, Peter Frigo, Marianne Koch, Rodrig Marculescu and Johannes Ott

    Citation: Journal of Ovarian Research 2019 12:91

    Content type: Research

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  18. Phospholipase C (PLC) can participate in cell proliferation, differentiation and aging. However, whether it has a function in apoptosis in porcine primary granulosa cells is largely uncertain. The objective of...

    Authors: Huali Chen, Youfu Yang, Youlin Wang, Yuan Li, Yamei He, Jiaxin Duan, Dejun Xu, Yifei Pei, Jianyong Cheng, Li Yang, Rongmao Hua, Xiaoya Li, Jie Wang, Xiaohan Jiang, Huanshan He, Lin Wu…

    Citation: Journal of Ovarian Research 2019 12:90

    Content type: Research

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  19. Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome. However, this entity in not ...

    Authors: Ana R. Flores, João Lobo, Francisco Nunes, Alexandra Rêma, Paula Lopes, Luís Carvalho, Carla Bartosch, Irina Amorim and Fátima Gärtner

    Citation: Journal of Ovarian Research 2019 12:89

    Content type: Case report

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  20. Epithelial ovarian cancer (EOC) is the majority ovarian cancer (OC) type with a poor prognosis. This present study aimed to investigate potential prognostic factors including albumin-to-fibrinogen ratio (AFR) ...

    Authors: Wen Yu, Zhongxue Ye, Xi Fang, Xingzhi Jiang and Yafen Jiang

    Citation: Journal of Ovarian Research 2019 12:88

    Content type: Research

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  21. This study aimed to examine the performance of the four risk of malignancy index (RMI) in discriminating borderline ovarian tumors (BOTs) and benign ovarian masses in daily clinical practice.

    Authors: Shuang Zhang, Shan Yu, Wenying Hou, Xiaoying Li, Chunping Ning, Yingnan Wu, Feng Zhang, Yu Fei Jiao, Leo Tsz On Lee and Litao Sun

    Citation: Journal of Ovarian Research 2019 12:87

    Content type: Research

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  22. To compare the chemoresistance and survival in patients with stage IIIC or IV epithelial ovarian cancer who were treated with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) or pri...

    Authors: Yan Gao, Yuan Li, Chunyu Zhang, Jinsong Han, Huamao Liang, Kun Zhang and Hongyan Guo

    Citation: Journal of Ovarian Research 2019 12:85

    Content type: Research

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  23. Circular RNAs (circRNAs) are a class of long non-coding RNAs (lncRNAs) which have a circular and closed loop structure. They are ubiquitous, stable, conserved and diverse RNA molecules with a range of activiti...

    Authors: Zahra Shabaninejad, Asma Vafadar, Ahmad Movahedpour, Younes Ghasemi, Afshin Namdar, Hadis Fathizadeh, Mohammad Hossein Pourhanifeh, Amir Savardashtaki and Hamed Mirzaei

    Citation: Journal of Ovarian Research 2019 12:84

    Content type: Review

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  24. The incidence of Cesarean has increased in recent years. The purpose of this study is to evaluate the effect of cesarean section on ovarian reserve.

    Authors: Ashraf Moini, Reihaneh Pirjani, Maryam Rabiei, Maryam Nurzadeh, Mahdi Sepidarkish, Reihaneh Hosseini and Ladan Hosseini

    Citation: Journal of Ovarian Research 2019 12:83

    Content type: Research

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  25. Polycystic ovary syndrome (PCOS) is an endocrine disease that is common in women in their reproductive period. Patients with this disease suffer from anovulation and hyperandrogenism. Ovulation induction with ...

    Authors: Sachiko Nagao, Tsuyoshi Baba, Yuya Fujibe, Sayaka Adachi, Keiko Ikeda, Miyuki Morishita, Yoshika Kuno, Hiroyuki Honnma, Toshiaki Endo, Tamotsu Kiya and Tsuyoshi Saito

    Citation: Journal of Ovarian Research 2019 12:82

    Content type: Research

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  26. Uterine corpus endometrial carcinoma (UCEC) is one of the most common cancer in female worldwide. PIK3CA has been proven to be a strong prognostic biomarker in UCEC. Nevertheless, current studies have not inve...

    Authors: Yinglian Pan, Li Ping Jia, Yuzhu Liu, Yixu Han and Qingchun Deng

    Citation: Journal of Ovarian Research 2019 12:81

    Content type: Research

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  27. Multiple targeted gene sequencing is seldom performed in both germline and somatic testing for ovarian cancer. This study is to evaluate the specific genetic alterations, including both somatic and germline mu...

    Authors: Wenhui Li, Di Shao, Lei Li, Ming Wu, Shuiqing Ma, Xianjie Tan, Sen Zhong, Fengming Guo, Zhe Wang and Mingzhi Ye

    Citation: Journal of Ovarian Research 2019 12:80

    Content type: Research

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  28. To explore the risk factors for the recurrence of endometrioma and the risk factors for the recurrence of endometriosis-related pain after long-term follow-up.

    Authors: Xiao-Yan Li, Xiao-Pei Chao, Jin-Hua Leng, Wen Zhang, Jun-Ji Zhang, Yi Dai, Jing-Hua Shi, Shuang-Zheng Jia, Xiao-Xuan Xu, Si-Kai Chen and Yu-Shi Wu

    Citation: Journal of Ovarian Research 2019 12:79

    Content type: Research

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  29. Reduction of the body iron stores can improve hyperandrogenemia and insulin resistance. This study aimed to compare clinical and para-clinical responses to the treatment of phlebotomy using oral contraceptive ...

    Authors: Samira Behboudi-Gandevani, Hayedeh Abtahi, Navid Saadat, Maryam Tohidi and Fahimeh Ramezani Tehrani

    Citation: Journal of Ovarian Research 2019 12:78

    Content type: Research

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  30. Granulosa cell tumors (GCTs) are derived from proliferating granulosa cells of the ovarian follicle. They are known for their late recurrence and most patients with an aggressive form die from their disease. T...

    Authors: Konstantin Bagnjuk, Verena Jasmin Kast, Astrid Tiefenbacher, Melanie Kaseder, Toshihiko Yanase, Alexander Burges, Lars Kunz, Doris Mayr and Artur Mayerhofer

    Citation: Journal of Ovarian Research 2019 12:76

    Content type: Research

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  31. The mechanism of the pathological change of polycystic ovary syndrome (PCOS) is still unclear. Previous studies have shown that PCOS is a chronic nonspecific low-grade inflammatory condition, and that heat sho...

    Authors: Gengxiang Wu, Xue Hu, Jinli Ding and Jing Yang

    Citation: Journal of Ovarian Research 2019 12:74

    Content type: Research

    Published on:

  32. In this study we aimed at retrospectively assessing in a homogeneous group of IVF patients whether the addition of Early Embryo Viability Assessment (Eeva™) to standard morphology increases the accuracy of emb...

    Authors: Alberto Revelli, Stefano Canosa, Andrea Carosso, Claudia Filippini, Carlotta Paschero, Gianluca Gennarelli, Luisa Delle Piane and Chiara Benedetto

    Citation: Journal of Ovarian Research 2019 12:73

    Content type: Research

    Published on:

  33. The majority of death-related ovarian cancer is epithelial ovarian cancer (EOC). Regarding the Federation of Gynecology and Obstetrics (FIGO) stage IV EOC, the 5-year overall survival (OS) has not changed in l...

    Authors: Jie-Ping Chen, Qi-Dan Huang, Ting Wan, Hua Tu, Hai-Feng Gu, Jun-Ya Cao and Ji-Hong Liu

    Citation: Journal of Ovarian Research 2019 12:72

    Content type: Research

    Published on:

  34. About 80 % of all women affected by ovarian cancer present with advanced stage disease at the time of diagnosis. Achieving complete cytoreduction is complicated when many small tumor spots are found. Yet, comp...

    Authors: Gatske M. Nieuwenhuyzen-de Boer, Jacoba van der Kooy and Heleen J. van Beekhuizen

    Citation: Journal of Ovarian Research 2019 12:71

    Content type: Review

    Published on:

  35. Mesenchymal stem cells (MSCs) have surfaced as ideal candidates for treatment of different therapeutically challenging diseases however their effect on cancer cells is not well determined. In this study, we in...

    Authors: C. Khalil, M. Moussa, A. Azar, J. Tawk, J. Habbouche, R. Salameh, A. Ibrahim and N Alaaeddine

    Citation: Journal of Ovarian Research 2019 12:70

    Content type: Research

    Published on:

  36. There is no consensus on the optimal chemotherapy regimen and the prognostic factors for ovarian large cell neuroendocrine carcinoma (LCNEC), a rare type of tumor. The objective of the present study is to pres...

    Authors: Xiaohang Yang, Junyu Chen and Ruiying Dong

    Citation: Journal of Ovarian Research 2019 12:69

    Content type: Case report

    Published on:

  37. Following publication of the original article [1], the authors opted to correct the incorrect e-mail address of the corresponding author from

    Authors: Ki Hyung Kim, Kyung Un Choi, Ahrong Kim, So Jung Lee, Jung Hee Lee, Dong Soo Suh, Byung-Su Kwon and Chungsu Hwang

    Citation: Journal of Ovarian Research 2019 12:68

    Content type: Correction

    Published on:

    The original article was published in Journal of Ovarian Research 2019 12:56

  38. Women with vanishing twin syndrome are associated with increased risks of adverse neonatal outcomes, such as preterm birth (PTB) and low birthweight (LBW), compared with those in singleton live births followin...

    Authors: Junfang Yan, Yichun Guan, Hongfang Fan, Mingkun Mu, Simin Sun, Wenjun Geng, Wei Zheng and Zhiying Xiao

    Citation: Journal of Ovarian Research 2019 12:67

    Content type: Research

    Published on:

  39. Laparoscopic cystectomy provides more favourable outcomes as regards the recurrence and subsequent clinical pregnancy rates. It is associated with significant reduction in the ovarian reserve due to the inevit...

    Authors: Mohamed F. Shaltout, Ahmad elsheikhah, Ahmed M. Maged, Moutaz M. Elsherbini, Sherif S. Zaki, Sherif Dahab and Rasha O. Elkomy

    Citation: Journal of Ovarian Research 2019 12:66

    Content type: Research

    Published on:

  40. Premature ovarian insufficiency (POI) is characterized by early loss of ovarian function that affects women before the age of 40. We aim to explore the protective effects of transcutaneous electrical acupoint ...

    Authors: Rongrong Tan, Yuheng He, Suyun Zhang, Danhua Pu and Jie Wu

    Citation: Journal of Ovarian Research 2019 12:65

    Content type: Research

    Published on:

  41. Serous carcinoma, the subtype of ovarian cancer has the highest occurrence and mortality in women. Proteomic profiling using mass spectrometry (MS) has been used to detect biomarkers in tissue s obtained from ...

    Authors: Haniyeh Bashi zadeh fakhar, Hakimeh Zali, Mostafa Rezaie-Tavirani, Roya Faraji Darkhaneh and Babak Babaabasi

    Citation: Journal of Ovarian Research 2019 12:64

    Content type: Research

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  42. The use of patient reported outcome measures (PROMs) has increased during the past decade, and the focus on how to use them has resulted in a more proactive application. Studies have shown that proactive use o...

    Authors: Anette Stolberg Kargo, Angela Coulter, Pernille Tine Jensen and Karina Dahl Steffensen

    Citation: Journal of Ovarian Research 2019 12:63

    Content type: Review

    Published on:

  43. All-trans retinoic acid (ATRA) is currently being used to treat hematological malignancies, given the ability to inhibit cell proliferation. This effect seems to be related to epigenetic changes of the TERT (Telo...

    Authors: Lorena Losi, Angela Lauriola, Erica Tazzioli, Gaia Gozzi, Letizia Scurani, Domenico D’Arca and Jean Benhattar

    Citation: Journal of Ovarian Research 2019 12:62

    Content type: Research

    Published on:

  44. Premature ovarian insufficiency (POI) leads to early loss of ovarian function in women aged < 40 years and is highly heterogeneous in etiology. The genetic etiology of this disorder remains unknown in most wom...

    Authors: Jing Zhe, Shiling Chen, Xin Chen, Yudong Liu, Ying Li, Xingyu Zhou and Jun Zhang

    Citation: Journal of Ovarian Research 2019 12:61

    Content type: Research

    Published on:

  45. To investigate whether miR-203a-3p can regulate the biological behaviors of ovarian cancer cells by targeting ATM to affect the Akt/GSK-3β/Snail signaling pathway.

    Authors: Hong-Yun Liu, Yu-Ying Zhang, Bao-Lian Zhu, Fu-Zhong Feng, Hai-Tang Zhang, Hua Yan and Bin Zhou

    Citation: Journal of Ovarian Research 2019 12:60

    Content type: Research

    Published on:

  46. To determine whether magnetic resonance (MR) imaging features combined with apparent diffusion coefficient (ADC) values could be used as a tool for categorizing ovarian epithelial cancer (OEC) and predicting surv...

    Authors: Guofu Zhang, Weigen Yao, Taotao Sun, Xuefen Liu, Peng Zhang, Jun Jin, Yu Bai, Keqin Hua and He Zhang

    Citation: Journal of Ovarian Research 2019 12:59

    Content type: Research

    Published on:

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