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  1. Content type: Review

    Ral interacting protein of 76 kDa (RLIP76) is multifunctional protein localized and distributed in the plasma membrane, cytosol, and nucleus of the cell. In tumorigenesis, RLIP76 emerges as a common feature fo...

    Authors: Dody Houston Billhaq and Seunghyung Lee

    Citation: Journal of Ovarian Research 2019 12:34

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  2. Content type: Review

    Previous studies about the prognostic value of the HIPEC have yielded controversial results. Therefore, this study aims to assess the impact of HIPEC on patients with ovarian cancer.

    Authors: Guyu Zhang, Yimin Zhu, Chongdong Liu, Guangming Chao, Ran Cui and Zhenyu Zhang

    Citation: Journal of Ovarian Research 2019 12:33

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  3. Content type: Case report

    Ovarian carcinosarcoma, which contains sarcomatous and carcinomatous components, is a very rare tumor. The carcinomatous component is often adenocarcinoma, and squamous cell carcinoma is extremely rare. We her...

    Authors: Atsushi Daimon, Satoe Fujiwara, Yoshimichi Tanaka, Tomohito Tanaka and Masahide Ohmichi

    Citation: Journal of Ovarian Research 2019 12:32

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  4. Content type: Research

    Hyperandrogenism is one of the cardinal symptoms in polycystic ovary syndrome and plays a key role in the pathogenesis of polycystic ovary syndrome. However, the precise effects and mechanisms of excess androg...

    Authors: Yuya Fujibe, Tsuyoshi Baba, Sachiko Nagao, Sayaka Adachi, Keiko Ikeda, Miyuki Morishita, Yoshika Kuno, Masahiro Suzuki, Masahito Mizuuchi, Hiroyuki Honnma, Toshiaki Endo and Tsuyoshi Saito

    Citation: Journal of Ovarian Research 2019 12:31

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  5. Content type: Research

    Increased activity of the chaperones Hsp70 and Hsp90 is a common feature of solid tumours. Translocase of the outer mitochondrial membrane 34 (Tomm34) is a cochaperone of both Hsp70 and Hsp90 that was found to...

    Authors: Petr Muller, Philip J. Coates, Rudolf Nenutil, Filip Trcka, Roman Hrstka, Josef Chovanec, Veronika Brychtova and Borivoj Vojtesek

    Citation: Journal of Ovarian Research 2019 12:30

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  6. Content type: Review

    Ovarian cancer is the 5th leading cause of death for women with cancer worldwide. In more than 70% of cases, it is only diagnosed at an advanced stage. Our study aims to give an update on the biological marker...

    Authors: Vincent Dochez, Hélène Caillon, Edouard Vaucel, Jérôme Dimet, Norbert Winer and Guillaume Ducarme

    Citation: Journal of Ovarian Research 2019 12:28

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  7. Content type: Research

    To analyze the clinicopathological characteristics of subsequent pelvic masses after hysterectomy for benign diseases, and to compare the masses following hysterectomy with or without simultaneous bilateral sa...

    Authors: Xiaopei Chao, Xiaoxia Wang, Yu Xiao, Mingliang Ji, Shu Wang, Honghui Shi, Qingbo Fan, Lan Zhu, Jinhua Leng, Dawei Sun and Jinghe Lang

    Citation: Journal of Ovarian Research 2019 12:27

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  8. Content type: Research

    Polycystic ovarian syndrome (PCOS) is a highly variable syndrome and one of the most common female endocrine disorders. Although the association inositols-glucomannan may represent a good therapeutic strategy ...

    Authors: Jacopo Troisi, Claudia Cinque, Luigi Giugliano, Steven Symes, Sean Richards, David Adair, Pierpaolo Cavallo, Laura Sarno, Giovanni Scala, Maria Caiazza and Maurizio Guida

    Citation: Journal of Ovarian Research 2019 12:25

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  9. Content type: Review

    Ovarian cancer is the primary cause of cancer-associated deaths among gynaecological malignancies. Increasing evidence suggests that microRNAs may be potential biomarkers for the diagnosis and prognosis of can...

    Authors: Xinshuai Wang, Dejiu Kong, Chaokun Wang, Xuezhen Ding, Li Zhang, Mengqi Zhao, Jing Chen, Xiangyun Xu, Xiaochen Hu, Junqiang Yang and Shegan Gao

    Citation: Journal of Ovarian Research 2019 12:24

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  10. Content type: Research

    Low-grade ovarian cancers represent up to 8% of all epithelial ovarian carcinomas (EOCs). Recent studies demonstrated that epithelial-mesenchymal transition (EMT) is crucial for the progression of EOCs. EMT pl...

    Authors: Paweł Sadłecki, Marek Grabiec, Dariusz Grzanka, Jakub Jóźwicki, Paulina Antosik and Małgorzata Walentowicz-Sadłecka

    Citation: Journal of Ovarian Research 2019 12:23

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  11. Content type: Research

    Normal pubertal ovary displays all stages of follicular development and a biased BAX/BCL2 protein ratio in favor of pro-apoptotic BAX protein comparable to the adult ovary. However, adolescents suffering malig...

    Authors: María Itatí Albamonte, Mirta Susana Albamonte, Ricardo M. Bou-Khair, Luis Zuccardi and Alfredo Daniel Vitullo

    Citation: Journal of Ovarian Research 2019 12:22

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  12. Content type: Research

    The cumulus expansion process is one of the LH mediated ovulatory processes. Hyaluronan synthase 2 (HAS2) regulates the synthesis of hyaluronic acid, the main component of the cumulus expansion process. Recent...

    Authors: Yuval Yung, Libby Ophir, Gil M. Yerushalmi, Micha Baum, Ariel Hourvitz and Ettie Maman

    Citation: Journal of Ovarian Research 2019 12:21

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  13. Content type: Research

    Common cancerous histological types associated with endometriosis are clear cell carcinoma (CCC) and endometrioid carcinoma (EC). CCC is regarded as an aggressive, chemoresistant histological subtype. Magnetic...

    Authors: Sachiko Morioka, Ryuji Kawaguchi, Yuki Yamada, Kana Iwai, Chiharu Yoshimoto and Hiroshi Kobayashi

    Citation: Journal of Ovarian Research 2019 12:20

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  14. Content type: Research

    Ovarian cancer (OC) is one of the most malignant gynecological tumors, associated with excess death rate (50–60%) in ovarian cancer patients. Particularly, among newly occurred ovarian cancer patients, 70% of ...

    Authors: Lei Zhang, Min Luo, Hongying Yang, Shaoyan Zhu, Xianliang Cheng and Chen Qing

    Citation: Journal of Ovarian Research 2019 12:19

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  15. Content type: Brief Communication

    Virotherapy represents a promising approach for ovarian cancer. In this regard, conditionally replicative adenovirus (CRAd) has been translated to the context of human clinical trials. Advanced design of CRAds...

    Authors: Rebeca González-Pastor, Ahmad Mohammad Ashshi, Adel Galal El-Shemi, Igor P. Dmitriev, Elena A. Kashentseva, Zhi Hong Lu, S. Peter Goedegebuure, Osvaldo L. Podhajcer and David T. Curiel

    Citation: Journal of Ovarian Research 2019 12:18

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  16. Content type: Research

    Relapsed epithelial ovarian cancer (EOC) is frequently treated with pegylated liposomal doxorubicin (PLD). Unfortunately, most patients do not benefit from treatment. Prediction of response is crucial to optim...

    Authors: Eleonora Ghisoni, Furio Maggiorotto, Fulvio Borella, Gloria Mittica, Sofia Genta, Gaia Giannone, Dionyssios Katsaros, Alberto Sciarrillo, Annamaria Ferrero, Ivana Sarotto, Jessica Erriquez, Maria Flavia Di Renzo, Massimo Aglietta and Giorgio Valabrega

    Citation: Journal of Ovarian Research 2019 12:17

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  17. Content type: Research

    The aim of the present study was to investigate the prognostic significance of preoperative complete blood count inflammatory markers in women operated for invasive Epithelial Ovarian Cancer (EOC).

    Authors: Mehmet Ufuk Ceran, Umit Tasdemir, Eser Colak and Tayfun Güngör

    Citation: Journal of Ovarian Research 2019 12:16

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  18. Content type: Research

    Ovarian cancer is the most lethal of all gynecologic malignancies. The relationship between sexual steroids receptors and ovarian cancer progression has been largely evaluated. The presence of progesterone rec...

    Authors: Enrique Pedernera, María J. Gómora, Flavia Morales-Vásquez, Delia Pérez-Montiel and Carmen Mendez

    Citation: Journal of Ovarian Research 2019 12:15

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  19. Content type: Research

    In ovarian endometriomas (OE), the expression statuses of various steroid hormone receptors are altered compared with their expression statuses in eutopic endometrium (EE). For example, in OE, the expressions ...

    Authors: Ryo Maekawa, Yumiko Mihara, Shun Sato, Maki Okada, Isao Tamura, Masahiro Shinagawa, Yuichiro Shirafuta, Haruka Takagi, Toshiaki Taketani, Hiroshi Tamura and Norihiro Sugino

    Citation: Journal of Ovarian Research 2019 12:14

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  20. Content type: Research

    Obesity is a chronic and multifactorial disease characterized by increased adipose tissue. In females, obesity leads to reduced ovulation and lower chances of conception in diseases like polycystic ovary syndr...

    Authors: R. O. A. Benevides, C. C. Vale, J. L. L. Fontelles, L. M. França, T. S. Teófilo, S. N. Silva, A. M. A. Paes and R. S. Gaspar

    Citation: Journal of Ovarian Research 2019 12:13

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  21. Content type: Research

    The aim of this study was to (1) evaluate the ability of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) parameters to predict suboptimal cytoreduction and (2) to create a...

    Authors: Gun Oh. Chong, Shin Young Jeong, Yoon Hee Lee, Hyun Jung Lee, Sang-Woo Lee, Hyung Soo Han, Dae Gy Hong and Yoon Soon Lee

    Citation: Journal of Ovarian Research 2019 12:12

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  22. Content type: Review

    Epithelial ovarian cancer is the most lethal gynecologic malignancy. In most women, it is diagnosed at an advanced stage, which largely explains the poor prognosis of this malignancy. Germline mutations of the...

    Authors: Angiolo Gadducci, Valentina Guarneri, Fedro Alessandro Peccatori, Graziana Ronzino, Giuseppa Scandurra, Claudio Zamagni, Paolo Zola and Vanda Salutari

    Citation: Journal of Ovarian Research 2019 12:9

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  23. Content type: Research

    Ovarian hyperstimulation syndrome remains a serious complication during in vitro fertilization cycles if high dose human chorionic gonadotropin (hCG) is used to trigger ovulation in high responder patients. Th...

    Authors: L. L. Engmann, B. S. Maslow, L. A. Kaye, D. W. Griffin, A. J. DiLuigi, D. W. Schmidt, D. R. Grow, J. C. Nulsen and C. A. Benadiva

    Citation: Journal of Ovarian Research 2019 12:8

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  24. Content type: Research

    Ovarian clear cell carcinoma (OCCC) is the second most common ovarian cancer after serous carcinoma in Japan. OCCC has a more unfavorable clinical outcome due to a poor response to platinum-based chemotherapy,...

    Authors: Hiroyuki Suzuki, Mitsutake Yano, Mariko Miyazawa, Masaki Miyazawa, Naoki Ogane, Kosei Hasegawa, Hitoshi Tsuda, Masayuki Yoshida, Ryugo Okagaki, Osamu Ishihara and Masanori Yasuda

    Citation: Journal of Ovarian Research 2019 12:7

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  25. Content type: Research

    Ovarian cancer (OC) is associated with high mortality in gynecological oncology; this is mainly due to the low diagnosis rate. Exosomal miRNA has demonstrated potential as a tumor biomarker. We aimed to explor...

    Authors: Ying Ying Su, Li Sun, Zhi Rui Guo, Jin Chang Li, Ting Ting Bai, Xiao Xiao Cai, Wen Han Li and Ye Fei Zhu

    Citation: Journal of Ovarian Research 2019 12:6

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  26. Content type: Research

    The aim of this study was to determine the effect of vitamin D and probiotic co-administration on mental health, hormonal, inflammatory and oxidative stress parameters in women with polycystic ovary syndrome (...

    Authors: Vahidreza Ostadmohammadi, Mehri Jamilian, Fereshteh Bahmani and Zatollah Asemi

    Citation: Journal of Ovarian Research 2019 12:5

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  27. Content type: Review

    There has been increasing interest in the role of endocannabinoids as critical modulators of the female reproductive processes. Endocannabinoids are natural ligands of cannabinoid, vanilloid, and peroxisome pr...

    Authors: O’Llenecia S. Walker, Alison C. Holloway and Sandeep Raha

    Citation: Journal of Ovarian Research 2019 12:3

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  28. Content type: Review

    Ovarian cancer remains the most fatal gynecologic malignancy worldwide due to delayed diagnosis as well as recurrence and drug resistance. Thus, the development of new tumor-related molecules with high sensiti...

    Authors: Kaipeng Xie, Chenyang Fu, Suli Wang, Hanzi Xu, Siyu Liu, Yang Shao, Zhen Gong, Xiaoli Wu, Bo Xu, Jing Han, Juan Xu, Pengfei Xu, Xuemei Jia and Jiangping Wu

    Citation: Journal of Ovarian Research 2019 12:1

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  29. Content type: Case report

    Sclerosing stromal tumors (SST) are rare, benign tumors classified as sex cord stromal tumors. To our knowledge, positron emission tomography with computed tomography (PET-CT) findings of SST have only been de...

    Authors: Hiroki Matsutani, Go Nakai, Takashi Yamada, Kazuhiro Yamamoto, Masahide Ohmichi and Yoshifumi Narumi

    Citation: Journal of Ovarian Research 2018 11:101

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  30. Content type: Case report

    Ovarian granulosa cell tumors (GCTs) are divided into adult GCT (AGCT) and juvenile GCT (JGCT). The AGCT is more common type, conversely, less than 5% of tumors are the JGCT and occur in mainly premenarchal gi...

    Authors: Yuki Inada, Go Nakai, Kazuhiro Yamamoto, Takashi Yamada, Yoshinobu Hirose, Yoshito Terai, Masahide Ohmichi and Yoshifumi Narumi

    Citation: Journal of Ovarian Research 2018 11:100

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  31. Content type: Research

    Ficus deltoidea is one of the well-known medicinal plants in Malaysia that is traditionally used by the Malay community to treat various ailments and for maintenance of female reproductive health. The objective o...

    Authors: Siti Sarah Mohamad Zaid, Shatrah Othman and Normadiah M. Kassim

    Citation: Journal of Ovarian Research 2018 11:99

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  32. Content type: Research

    Premature ovulation occurs at a high rate in natural-cycle in vitro fertilization (IVF), and cycle cancellation further hampers the overall efficiency of the procedure. While lower levels of estradiol (E2) are...

    Authors: Xuefeng Lu, Shuzin Khor, Qianqian Zhu, Lihua Sun, Yun Wang, Qiuju Chen, Ling Wu, Yonglun Fu, Hui Tian, Qifeng Lyu, Renfei Cai and Yanping Kuang

    Citation: Journal of Ovarian Research 2018 11:96

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  33. Content type: Research

    It has been shown – mostly in animal models - that circadian clock genes are expressed in granulosa cells and in corpora luteum and might be essential for the ovulatory process and steroidogenesis.

    Authors: Amnon Brzezinski, A. Saada, H. Miller, NA Brzezinski-Sinai and A. Ben-Meir

    Citation: Journal of Ovarian Research 2018 11:95

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  34. Content type: Research

    Epithelial ovarian cancer is one of the most severe public health threats in women. Since it is still challenging to screen in early stages, identification of core genes that play an essential role in epithel...

    Authors: Wenyu Li, Zheran Liu, Bowen Liang, Siyang Chen, Xinping Zhang, Xiaoqin Tong, Weiming Lou, Lulu Le, Xiaoli Tang and Fen Fu

    Citation: Journal of Ovarian Research 2018 11:94

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  35. Content type: Research

    Luteolin, a polyphenolic flavone, has been demonstrated to exert anti-tumor activity in various cancer types. Cisplatin drug resistance is a major obstacle in the management of ovarian cancer. In the present s...

    Authors: Haixia Wang, Youjun Luo, Tiankui Qiao, Zhaoxia Wu and Zhonghua Huang

    Citation: Journal of Ovarian Research 2018 11:93

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  36. Content type: Research

    The purpose of this study is to assess the preoperative evaluation of an adnexal mass using the GI-RADS classification and to verify whether CA-125 measurement can offer any additional benefits to the GI-RADS-...

    Authors: Michal Migda, Migda Bartosz, Marian S. Migda, Marcin Kierszk, Gieryn Katarzyna and Marek Maleńczyk

    Citation: Journal of Ovarian Research 2018 11:92

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  37. Content type: Research

    The purpose of this case-control study was to compare the prognoses of women with stage III mucinous ovarian carcinoma (MOC) who received maximal or optimal cytoreduction followed by paclitaxel plus carboplati...

    Authors: Zeliha Firat Cuylan, Emine Karabuk, Murat OZ, Ahmet Taner Turan, Mehmet M. Meydanli, Salih Taskin, Mustafa Erkan Sari, Hanifi Sahin, Suat C. Ulukent, Ozgur Akbayir, Kemal Gungorduk, Tayfun Gungor, Mehmet F. Kose and Ali Ayhan

    Citation: Journal of Ovarian Research 2018 11:91

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  38. Content type: Research

    The death-domain-associated protein (DAXX) was originally identified as a protein that binds to the transmembrane death receptor FAS and enhances both FAS-induced and transforming growth factor-β-dependent apo...

    Authors: Sheng-Bing Liu, Xue-Ping Lin, Ying Xu, Zhong-Fei Shen and Wei-Wei Pan

    Citation: Journal of Ovarian Research 2018 11:90

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  39. Content type: Research

    Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between neoplasms can be unique, allowing for distinctions in...

    Authors: Julie A. MacDonald, Niharika Kura, Carleigh Sussman and Dori C. Woods

    Citation: Journal of Ovarian Research 2018 11:89

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  40. Content type: Review

    Ovarian cancer has emerged as one of the leading cause of gynecological malignancies. So far, the measurement of CA125 and HE4 concentrations in blood and transvaginal ultrasound examination are essential ovar...

    Authors: Agata Swiatly, Szymon Plewa, Jan Matysiak and Zenon J. Kokot

    Citation: Journal of Ovarian Research 2018 11:88

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  41. Content type: Research

    Fibroblast growth factor 13 (FGF13) is one of the most highly expressed FGF family members in adult mouse ovary. However, its precise roles in ovarian function remain largely unknown. We sought to evaluate the...

    Authors: Yu Liu, Shengxian Li, Tao Tao, Xiaoxue Li, Qinling Zhu, Yu Liao, Jing Ma, Yun Sun and Wei Liu

    Citation: Journal of Ovarian Research 2018 11:87

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  42. Content type: Case report

    Ovarian cancer is the second most common gynecologic malignancy. As the primary imaging modality, computed tomography (CT) can provide staging information for preoperative planning and determination of surgica...

    Authors: Yi-ren Jin, Xie-lan Yang, Qin-qing Li, Zhi-ling Yan, Hong-ying Yang and Chengde Liao

    Citation: Journal of Ovarian Research 2018 11:86

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