Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ: Cancer statistics, 2009. CA Cancer J Clin 2009, 59: 225–249. 10.3322/caac.20006
Article
PubMed
Google Scholar
Armstrong DK: Relapsed ovarian cancer: challenges and management strategies for a chronic disease. Oncologist 2002, 7(Suppl 5):20–28. 10.1634/theoncologist.7-suppl_5-20
Article
CAS
PubMed
Google Scholar
Markman M: Pharmaceutical management of ovarian cancer: current status. Drugs 2008, 68: 771–789. 10.2165/00003495-200868060-00004
Article
CAS
PubMed
Google Scholar
Markman M, Webster K, Zanotti K, Peterson G, Kulp B, Belinson J: Survival following the documentation of platinum and taxane resistance in ovarian cancer: a single institution experience involving multiple phase 2 clinical trials. Gynecol Oncol 2004, 93: 699–701. 10.1016/j.ygyno.2004.03.023
Article
CAS
PubMed
Google Scholar
Borst P, Rottenberg S, Jonkers J: How do real tumors become resistant to cisplatin? Cell Cycle 2008, 7: 1353–1359.
Article
CAS
PubMed
Google Scholar
Herzog TJ, Pothuri B: Ovarian cancer: a focus on management of recurrent disease. Nat Clin Pract Oncol 2006, 3: 604–611. 10.1038/ncponc0637
Article
CAS
PubMed
Google Scholar
Alvarez RD, Huh WK, Khazaeli MB, Meredith RF, Partridge EE, Kilgore LC, Grizzle WE, Shen S, Austin JM, Barnes MN, et al.: A Phase I study of combined modality (90)Yttrium-CC49 intraperitoneal radioimmunotherapy for ovarian cancer. Clin Cancer Res 2002, 8: 2806–2811.
CAS
PubMed
Google Scholar
Meredith RF, Buchsbaum DJ, Alvarez RD, LoBuglio AF: Brief overview of preclinical and clinical studies in the development of intraperitoneal radioimmunotherapy for ovarian cancer. Clin Cancer Res 2007, 13: 5643s-5645s. 10.1158/1078-0432.CCR-07-0985
Article
CAS
PubMed
Google Scholar
Meenakshi Kuhar SI, Neeta Singh: Curcumin and Quercetin Combined with Cisplatin to Induce Apoptosis in Human Laryngeal Carcinoma Hep-2 Cells through the Mitochondrial Pathway. Journal of Cancer Molecules 2007, 3: 121–128.
Google Scholar
Cheah YH, Nordin FJ, Sarip R, Tee TT, Azimahtol HL, Sirat HM, Rashid BA, Abdullah NR, Ismail Z: Combined xanthorrhizol-curcumin exhibits synergistic growth inhibitory activity via apoptosis induction in human breast cancer cells MDA-MB-231. Cancer Cell Int 2009, 9: 1. 10.1186/1475-2867-9-1
Article
PubMed Central
PubMed
Google Scholar
Siddiqui IA, Malik A, Adhami VM, Asim M, Hafeez BB, Sarfaraz S, Mukhtar H: Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis. Oncogene 2008, 27: 2055–2063. 10.1038/sj.onc.1210840
Article
CAS
PubMed
Google Scholar
Bal Krishnan Jaggi SCC, Meena Jaggi : Review of Curcumin Effects on Signaling Pathways in Cancer. Proceedings of the South Dakota Academy of Science 2007, 86: 283–293.
Google Scholar
Karmakar S, Banik NL, Patel SJ, Ray SK: Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cells. Neurosci Lett 2006, 407: 53–58. 10.1016/j.neulet.2006.08.013
Article
CAS
PubMed
Google Scholar
Shishodia S, Amin HM, Lai R, Aggarwal BB: Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem Pharmacol 2005, 70: 700–713. 10.1016/j.bcp.2005.04.043
Article
CAS
PubMed
Google Scholar
Shishodia S, Chaturvedi MM, Aggarwal BB: Role of curcumin in cancer therapy. Curr Probl Cancer 2007, 31: 243–305. 10.1016/j.currproblcancer.2007.04.001
Article
PubMed
Google Scholar
Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, et al.: Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 2001, 21: 2895–2900.
CAS
PubMed
Google Scholar
Garcea G, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ, Berry DP: Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration. Br J Cancer 2004, 90: 1011–1015. 10.1038/sj.bjc.6601623
Article
PubMed Central
CAS
PubMed
Google Scholar
Hamaguchi K, Godwin AK, Yakushiji M, O'Dwyer PJ, Ozols RF, Hamilton TC: Cross-resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines. Cancer Res 1993, 53: 5225–5232.
CAS
PubMed
Google Scholar
Chauhan SC, Vannatta K, Ebeling MC, Vinayek N, Watanabe A, Pandey KK, Bell MC, Koch MD, Aburatani H, Lio Y, Jaggi M: Expression and functions of transmembrane mucin MUC13 in ovarian cancer. Cancer Res 2009, 69: 765–774. 10.1158/0008-5472.CAN-08-0587
Article
CAS
PubMed
Google Scholar
Jaggi M, Chauhan SC, Du C, Balaji KC: Bryostatin 1 modulates beta-catenin subcellular localization and transcription activity through protein kinase D1 activation. Mol Cancer Ther 2008, 7: 2703–2712. 10.1158/1535-7163.MCT-08-0119
Article
CAS
PubMed
Google Scholar
Govender T, Stolnik S, Garnett MC, Illum L, Davis SS: PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J Control Release 1999, 57: 171–185. 10.1016/S0168-3659(98)00116-3
Article
CAS
PubMed
Google Scholar
Bisht S, Feldmann G, Soni S, Ravi R, Karikar C, Maitra A, Maitra A: Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J Nanobiotechnology 2007, 5: 3. 10.1186/1477-3155-5-3
Article
PubMed Central
PubMed
Google Scholar
Dong S, Roman M: Fluorescently labeled cellulose nanocrystals for bioimaging applications. J Am Chem Soc 2007, 129: 13810–13811. 10.1021/ja076196l
Article
CAS
PubMed
Google Scholar
Gavert N, Ben-Ze'ev A: beta-Catenin signaling in biological control and cancer. J Cell Biochem 2007, 102: 820–828. 10.1002/jcb.21505
Article
CAS
PubMed
Google Scholar
Wheelock MJ, Johnson KR: Cadherin-mediated cellular signaling. Curr Opin Cell Biol 2003, 15: 509–514. 10.1016/S0955-0674(03)00101-7
Article
CAS
PubMed
Google Scholar
Gatcliffe TA, Monk BJ, Planutis K, Holcombe RF: Wnt signaling in ovarian tumorigenesis. Int J Gynecol Cancer 2008, 18: 954–962. 10.1111/j.1525-1438.2007.01127.x
Article
PubMed Central
CAS
PubMed
Google Scholar
Sarrio D, Moreno-Bueno G, Sanchez-Estevez C, Banon-Rodriguez I, Hernandez-Cortes G, Hardisson D, Palacios J: Expression of cadherins and catenins correlates with distinct histologic types of ovarian carcinomas. Hum Pathol 2006, 37: 1042–1049. 10.1016/j.humpath.2006.03.003
Article
CAS
PubMed
Google Scholar
Dehner M, Hadjihannas M, Weiske J, Huber O, Behrens J: Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1. J Biol Chem 2008, 283: 19201–19210. 10.1074/jbc.M710366200
Article
CAS
PubMed
Google Scholar
Huang M, Wang Y, Sun D, Zhu H, Yin Y, Zhang W, Yang S, Quan L, Bai J, Wang S, et al.: Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis. BMC Cancer 2006, 6: 221. 10.1186/1471-2407-6-221
Article
PubMed Central
PubMed
Google Scholar
Yang F, Zeng Q, Yu G, Li S, Wang CY: Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC. Cell Signal 2006, 18: 679–687. 10.1016/j.cellsig.2005.06.015
Article
CAS
PubMed
Google Scholar
Liu M, Yang S, Wang Y, Zhu H, Yan S, Zhang W, Quan L, Bai J, Xu N: EB1 acts as an oncogene via activating beta-catenin/TCF pathway to promote cellular growth and inhibit apoptosis. Mol Carcinog 2009, 48: 212–219. 10.1002/mc.20471
Article
CAS
PubMed
Google Scholar
Anand P, Nair HB, Sung B, Kunnumakkara AB, Yadav VR, Tekmal RR, Aggarwal BB: Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo. Biochem Pharmacol 2010, 79: 330–338. 10.1016/j.bcp.2009.09.003
Article
PubMed Central
CAS
PubMed
Google Scholar
Shaikh J, Ankola DD, Beniwal V, Singh D, Kumar MN: Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci 2009, 37: 223–230. 10.1016/j.ejps.2009.02.019
Article
CAS
PubMed
Google Scholar
Ponnusamy MP, Venkatraman G, Singh AP, Chauhan SC, Johansson SL, Jain M, Smith L, Davis JS, Remmenga SW, Batra SK: Expression of TAG-72 in ovarian cancer and its correlation with tumor stage and patient prognosis. Cancer Lett 2007, 251: 247–257. 10.1016/j.canlet.2006.11.025
Article
CAS
PubMed
Google Scholar
Morris PG, Fornier MN: Microtubule active agents: beyond the taxane frontier. Clin Cancer Res 2008, 14: 7167–7172. 10.1158/1078-0432.CCR-08-0169
Article
CAS
PubMed
Google Scholar
Perez EA: Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer. Breast Cancer Res Treat 2009, 114: 195–201. 10.1007/s10549-008-0005-6
Article
CAS
PubMed
Google Scholar
Krishna R, Mayer LD: Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm Sci 2000, 11: 265–283. 10.1016/S0928-0987(00)00114-7
Article
CAS
PubMed
Google Scholar
Chendil D, Ranga RS, Meigooni D, Sathishkumar S, Ahmed MM: Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene 2004, 23: 1599–1607. 10.1038/sj.onc.1207284
Article
CAS
PubMed
Google Scholar
Javvadi P, Segan AT, Tuttle SW, Koumenis C: The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol Pharmacol 2008, 73: 1491–1501. 10.1124/mol.107.043554
Article
PubMed Central
CAS
PubMed
Google Scholar
Chan MM, Fong D, Soprano KJ, Holmes WF, Heverling H: Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents. J Cell Physiol 2003, 194: 63–70. 10.1002/jcp.10186
Article
CAS
PubMed
Google Scholar
Chirnomas D, Taniguchi T, de la Vega M, Vaidya AP, Vasserman M, Hartman AR, Kennedy R, Foster R, Mahoney J, Seiden MV, D'Andrea AD: Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway. Mol Cancer Ther 2006, 5: 952–961. 10.1158/1535-7163.MCT-05-0493
Article
CAS
PubMed
Google Scholar
Montopoli M, Ragazzi E, Froldi G, Caparrotta L: Cell-cycle inhibition and apoptosis induced by curcumin and cisplatin or oxaliplatin in human ovarian carcinoma cells. Cell Prolif 2009, 42: 195–206. 10.1111/j.1365-2184.2009.00585.x
Article
CAS
PubMed
Google Scholar
Frenzel A, Grespi F, Chmelewskij W, Villunger A: Bcl2 family proteins in carcinogenesis and the treatment of cancer. Apoptosis 2009, 14: 584–596. 10.1007/s10495-008-0300-z
Article
PubMed Central
CAS
PubMed
Google Scholar
Lopez-Lazaro M: Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Mol Nutr Food Res 2008, 52(Suppl 1):S103–127.
PubMed
Google Scholar
Hsu CH, Cheng AL: Clinical studies with curcumin. Adv Exp Med Biol 2007, 595: 471–480. full_text
Article
PubMed
Google Scholar
Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, Hewitt HR, Marczylo TH, Morgan B, Hemingway D, Plummer SM, et al.: Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance. Clin Cancer Res 2004, 10: 6847–6854. 10.1158/1078-0432.CCR-04-0744
Article
CAS
PubMed
Google Scholar
Ireson C, Orr S, Jones DJ, Verschoyle R, Lim CK, Luo JL, Howells L, Plummer S, Jukes R, Williams M, et al.: Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res 2001, 61: 1058–1064.
CAS
PubMed
Google Scholar
Ireson CR, Jones DJ, Orr S, Coughtrie MW, Boocock DJ, Williams ML, Farmer PB, Steward WP, Gescher AJ: Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol Biomarkers Prev 2002, 11: 105–111.
CAS
PubMed
Google Scholar
Singh R, Lillard JW Jr: Nanoparticle-based targeted drug delivery. Exp Mol Pathol 2009, 86: 215–223. 10.1016/j.yexmp.2008.12.004
Article
PubMed Central
CAS
PubMed
Google Scholar
Emerich DF, Thanos CG: Targeted nanoparticle-based drug delivery and diagnosis. J Drug Target 2007, 15: 163–183. 10.1080/10611860701231810
Article
CAS
PubMed
Google Scholar
Byrne JD, Betancourt T, Brannon-Peppas L: Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev 2008, 60: 1615–1626. 10.1016/j.addr.2008.08.005
Article
CAS
PubMed
Google Scholar
Davis ME, Chen ZG, Shin DM: Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 2008, 7: 771–782. 10.1038/nrd2614
Article
CAS
PubMed
Google Scholar
Kukowska-Latallo JF, Candido KA, Cao Z, Nigavekar SS, Majoros IJ, Thomas TP, Balogh LP, Khan MK, Baker JR Jr: Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res 2005, 65: 5317–5324. 10.1158/0008-5472.CAN-04-3921
Article
CAS
PubMed
Google Scholar