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  1. Content type: Review

    Reproductive aging is a natural process that occurs in all women, eventually leading to reproductive senescence and menopause. Over the past half century there has been a trend towards delayed motherhood. Post...

    Authors: Rani Fritz and Sangita Jindal

    Citation: Journal of Ovarian Research 2018 11:66

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  2. Content type: Research

    In recent years, autotransplantation of cryopreserved ovarian tissue became a promising approach to preserve female fertility. The slow freezing is the most effective technique which resulted in greater live b...

    Authors: Dmitry Nikiforov, Valentina Russo, Delia Nardinocchi, Nicola Bernabò, Mauro Mattioli and Barbara Barboni

    Citation: Journal of Ovarian Research 2018 11:65

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  3. Content type: Research

    Ovarian cancer is the most lethal of gynecological malignancies. Fourier Transform Infrared (FTIR) spectroscopy has gradually developed as a convenient, inexpensive and non-destructive technique for the study ...

    Authors: Lei Li, Xiaoning Bi, Hengzi Sun, Simiao Liu, Mei Yu, Ying Zhang, Shifu Weng, Limin Yang, Yanan Bao, Jinguang Wu, Yizhuang Xu and Keng Shen

    Citation: Journal of Ovarian Research 2018 11:64

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  4. Content type: Research

    In the recent years, vitamin D has become a topical subject and a focus of research not only in reproductive medicine but across many medical disciplines. In reproductive medicine, studies have identified an a...

    Authors: Soheila Arefi, Gholamreza Khalili, Homa Iranmanesh, Fattaneh Farifteh, Ahmad Hosseini, Human M. Fatemi and Barbara Lawrenz

    Citation: Journal of Ovarian Research 2018 11:62

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  5. Content type: Research

    To demonstrate the use of surface-enhanced Raman spectroscopy (SERS) to determine sialic acid (SA) levels in saliva using silver nanoparticles as substrates, in adnexal mass patients scheduled for surgical int...

    Authors: José de Jesús Zermeño-Nava, Marco Ulises Martínez-Martínez, Ana Laura Rámirez-de-Ávila, Aida Catalina Hernández-Arteaga, Ma. Guadalupe García-Valdivieso, Alondra Hernández-Cedillo, Miguel José-Yacamán and Hugo Ricardo Navarro-Contreras

    Citation: Journal of Ovarian Research 2018 11:61

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  6. Content type: Research

    This study sought to clarify the roles of Anti-müllerian hormone (AMH) and follicle stimulating hormone (FSH) in predicting live birth, especially in patients with discordant AMH and FSH. A large IVF data set ...

    Authors: Shunping Wang, Yi Zhang, Virginia Mensah, Warren J. Huber III, Yen-Tsung Huang and Ruben Alvero

    Citation: Journal of Ovarian Research 2018 11:60

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  7. Content type: Research

    Improvements in vitrification and frozen embryo transfer (FET) technologies have rapidly increased, and some evidence suggests that FET may increase pregnancy rates and lead to more favourable perinatal outcom...

    Authors: Junwei Zhang, Mingze Du, Zhe Li, Lulu Wang, Jijun Hu, Bei Zhao, Yingying Feng, Xiaolin Chen and Lijun Sun

    Citation: Journal of Ovarian Research 2018 11:59

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  8. Content type: Research

    Ovarian clear cell carcinoma is a distinct histologic subtype with grave survival. The underlying molecular mechanism is not fully elucidated. However, we don’t have many cell lines, which are useful experimen...

    Authors: Wei Jiang, Shuang Ye, Libing Xiang, Wentao Yang, Tiancong He, Xuan Pei, Lin Guo and Huijuan Yang

    Citation: Journal of Ovarian Research 2018 11:58

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  9. Content type: Research

    Primary cytoreductive surgery followed by adjuvant chemotherapy is the standard treatment for advanced epithelial ovarian cancer. The average interval between surgery and chemotherapy initiation is approximate...

    Authors: Yooyoung Lee, Alexandra Kollara, Taymaa May and Theodore J. Brown

    Citation: Journal of Ovarian Research 2018 11:56

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  10. Content type: Research

    PCOS is a reproductive hormonal abnormality and a metabolic disorder. It is frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, and oxidative stress. We aim to investigate th...

    Authors: Selenay Furat Rencber, Sema Kurnaz Ozbek, Ceyla Eraldemır, Zehra Sezer, Tugba Kum, Sureyya Ceylan and Elif Guzel

    Citation: Journal of Ovarian Research 2018 11:55

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  11. Content type: Research

    This study was to determine age-specific impact of fertility preserving surgery on disease-specific survival in women with stage I borderline ovarian tumors (BOTs). Patients diagnosed during 1988–2000 were sel...

    Authors: Haiyan Sun, Xi Chen, Tao Zhu, Nanfang Liu, Aijun Yu and Shihua Wang

    Citation: Journal of Ovarian Research 2018 11:54

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  12. Content type: Research

    Considered as the precursor lesion of a subset of ovarian clear cell carcinoma (OCCC), the prognostic role of endometriosis in OCCC patients remains controversial. This study aimed to investigate the prognosti...

    Authors: Ting Zhao, Yu Shao, Yan Liu, Xiao Wang, Luyao Guan and Yuan Lu

    Citation: Journal of Ovarian Research 2018 11:53

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  13. Content type: Case Report

    Alpha-fetoprotein (AFP) is a useful tumor marker for ovarian germ cell tumors, particularly yolk sac tumor (YST). It is valuable for both diagnosis and further follow-up. Epithelial ovarian carcinoma (EOC) rar...

    Authors: Wei-Ting Chao, Chia-Hao Liu, Chiung-Ru Lai, Yi-Jen Chen, Chi-Mu Chuang and Peng-Hui Wang

    Citation: Journal of Ovarian Research 2018 11:52

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  14. Content type: Research

    Menopause is the most important sign of aging in women, and the ovary is the organ most sensitive to aging. Quercetin is a potential antioxidant and free radical scavenger that is widely found in fruits, veget...

    Authors: Jiao Wang, Xin Qian, Qiang Gao, Chunmei Lv, Jie Xu, Hongbo Jin and Hui Zhu

    Citation: Journal of Ovarian Research 2018 11:51

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  15. Content type: Review

    Treatment for advanced ovarian cancer is rarely curative; three quarters of patients with advanced disease relapse and ultimately die with resistant disease. Improving patient outcomes will require the introdu...

    Authors: Mary Ellen Gee, Zahra Faraahi, Aiste McCormick and Richard J. Edmondson

    Citation: Journal of Ovarian Research 2018 11:50

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  16. Content type: Research

    The treatment of newly diagnosed advanced epithelial ovarian cancer (EOC) was predicted by an ovarian cancer computed tomography (CT) evaluation model combined with serum CA125.

    Authors: Lu Qin, Huming Huang, Mengjie Chen, Yuejuan Liang and He Wang

    Citation: Journal of Ovarian Research 2018 11:49

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  17. Content type: Research

    The clinical treatment of ovarian cancer with ascites is problematic. The main reasons for treatment failure are the susceptibility to intraperitoneal metastasis and chemotherapeutic drug resistance. The purpo...

    Authors: Duanyang Liu, Dan Kong, Jing Li, Lei Gao, Di Wu, Yu Liu, Weiwei Yang, Lei Zhang, Jiang Zhu and Xiaoming Jin

    Citation: Journal of Ovarian Research 2018 11:47

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  18. Content type: Research

    To assess and compare the influence of three fibroid treatment options: supracervical hysterectomy, ulipristal acetate and uterine artery embolization on ovarian reserve.

    Authors: Piotr Czuczwar, Anna Stepniak, Pawel Milart, Tomasz Paszkowski and Slawomir Wozniak

    Citation: Journal of Ovarian Research 2018 11:45

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  19. Content type: Case report

    Although cases of cervical squamous cell carcinoma metastatic to the ovary have been previously documented, we report the first case of superficially invasive squamous cell carcinoma metastatic to the ovary.

    Authors: Minfen Zhang, Elena Lucas, Hanzhen Xiong, Shaoyan Liu, Kyle Molberg, Qingping Jiang and Wenxin Zheng

    Citation: Journal of Ovarian Research 2018 11:44

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  20. Content type: Research

    Ovarian cancer is the major cause of death among gynecologic cancers with 75% of patients diagnosed with advanced disease, and only 20% of these patients having a survival duration of five years. Treatments bl...

    Authors: Maureen L. Drakes, Swati Mehrotra, Monica Aldulescu, Ronald K. Potkul, Yueying Liu, Anne Grisoli, Cara Joyce, Timothy E. O’Brien, M. Sharon Stack and Patrick J. Stiff

    Citation: Journal of Ovarian Research 2018 11:43

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  21. Content type: Research

    Optimal cytoreduction (macroscopic Residual Tumor, RT = 0) is the best survival predictor factor in epithelial ovarian cancer (EOC). It doesn’t exist a consolidated criteria to predict optimal surgical resecti...

    Authors: Eleonora Ghisoni, Dionyssios Katsaros, Furio Maggiorotto, Massimo Aglietta, Marco Vaira, Michele De Simone, Gloria Mittica, Gaia Giannone, Manuela Robella, Sofia Genta, Fabiola Lucchino, Francesco Marocco, Fulvio Borella, Giorgio Valabrega and Riccardo Ponzone

    Citation: Journal of Ovarian Research 2018 11:42

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  22. Content type: Research

    To analyze the clinical characteristics and chemo-resistance related factors of patients with resistant and non-resistant endometriosis-associated ovarian cancer (ovarian clear cell carcinoma and endometrioid ...

    Authors: Tong Ren, Ting-Ting Sun, Shu Wang, Jian Sun, Yang Xiang, Keng Shen and Jing-He Lang

    Citation: Journal of Ovarian Research 2018 11:40

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  23. Content type: Research

    The anti-tumor effects of S-allylcysteine (SAC), a water-soluble garlic derivative, on human ovarian cancer cells have been previous studied in vitro and in vivo models but the precise epigenetic molecular mec...

    Authors: Yasi Xu, Dan Su, Lucheng Zhu, Shirong Zhang, Shenglin Ma, Kan Wu, Qiang Yuan and Nengming Lin

    Citation: Journal of Ovarian Research 2018 11:39

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  24. Content type: Research

    Myo-inositol (MI), successfully used in polycystic ovary syndrome (PCOS), was administered with α-LA to exploit its action of favouring the passage of other molecules through biological barriers, and also cons...

    Authors: Mario Montanino Oliva, Giovanna Buonomo, Marco Calcagno and Vittorio Unfer

    Citation: Journal of Ovarian Research 2018 11:38

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  25. Content type: Research

    The use of long protocol during controlled ovarian stimulation for assisted reproduction attracts high dosage of gonadotropins. High dose of gonadotropins can be detrimental to oocyte development, which affect...

    Authors: Humphrey Ochin, Xiang Ma, Lin Wang, Xuan Li, Jie Song, Yan Meng, Jiandong Shen, Yu-Gui Cui and Jiayin Liu

    Citation: Journal of Ovarian Research 2018 11:37

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  26. Content type: Research

    Ovarian cancer stem cells (OCSCs) contribute to the poor prognosis of ovarian cancer. Involvement of the androgen receptor (AR) in the malignant behaviors of other tumors has been reported. However, whether AR...

    Authors: Kaijian Ling, Lupin Jiang, Shi Liang, Joseph Kwong, Leiyan Yang, Yudi Li, PingYin, Qingchun Deng and Zhiqing Liang

    Citation: Journal of Ovarian Research 2018 11:36

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    The Correction to this article has been published in Journal of Ovarian Research 2019 12:11

  27. Content type: Research

    Fertility preservation by whole ovary cryopreservation and transplantation (WOCP&TP) with vascular anastomosis requires successful cryopreservation. In this study, we investigated the possibility of restoring ...

    Authors: Yan Ding, Jia-liang Shao, Jun-wei Li, Ying Zhang, Kai-hua Hong, Ke-qin Hua and Xiang Wang

    Citation: Journal of Ovarian Research 2018 11:35

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  28. Content type: Research

    The granulosa cells are indispensable for follicular development and its function is orchestrated by several genes, which in turn posttranscriptionally regulated by microRNAs (miRNA). In our previous study, th...

    Authors: Hari Om Pande, Dawit Tesfaye, Michael Hoelker, Samuel Gebremedhn, Eva Held, Christiane Neuhoff, Ernst Tholen, Karl Schellander and Dessie Salilew Wondim

    Citation: Journal of Ovarian Research 2018 11:34

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  29. Content type: Research

    In recent years, cancer rates have been rising among reproductive-age women. Thus, chemotherapy exposure has become an important cause of premature ovarian failure (POF). There has been growing interest regard...

    Authors: Rauf Melekoglu, Osman Ciftci, Sevil Eraslan, Asli Cetin and Nese Basak

    Citation: Journal of Ovarian Research 2018 11:33

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  30. Content type: Research

    KLK10 exon 3 hypermethylation correlated to tumor-specific lack of KLK10 expression in cancer cell lines and primary tumors. In the present study we investigate the possible role of KLK10 exon 3 methylation in ov...

    Authors: Mustafa A. El Sherbini, Amal A. Mansour, Maha M. Sallam, Emtiaz A. Shaban, Zeinab A. Shehab ElDin and Amr H. El-Shalakany

    Citation: Journal of Ovarian Research 2018 11:32

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  31. Content type: Research

    B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1) might be an appropriate biomarker in the management of epithelial ovarian cancer (EOC). However, the biological role of BMI1 and its rele...

    Authors: Qianying Zhao, Qiuhong Qian, Dongyan Cao, Jiaxin Yang, Ting Gui and Keng Shen

    Citation: Journal of Ovarian Research 2018 11:31

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  32. Content type: Research

    Synchronous endometrial disorders have been poorly studied in women with endometrioid borderline ovarian tumors (EBOT). The aims of this study were to investigate the risk of endometrial disorders among women ...

    Authors: Shuang-zheng Jia, Jun-ji Zhang, Jun-jun Yang, Yang Xiang, Zhiyong Liang and Jin-hua Leng

    Citation: Journal of Ovarian Research 2018 11:30

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  33. Content type: Research

    Obesity has been linked to several types of cancers including ovarian cancer. Retinol binding protein 4 (RBP4) is an adipokine that drives the development of hyperinsulinemia and type II diabetes in obesity pa...

    Authors: Yanyan Wang, Yilin Wang and Zhenyu Zhang

    Citation: Journal of Ovarian Research 2018 11:29

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  34. Content type: Research

    In recent years the question of the lack of transparency in clinical research has been debated by clinicians, researchers, citizens and their representatives, authors and publishers. This is particularly impor...

    Authors: Anna Roberto, Silvia Radrezza and Paola Mosconi

    Citation: Journal of Ovarian Research 2018 11:28

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  35. Content type: Research

    Ovarian cancer is the leading gynecologic cancer diagnosed in North America and because related symptoms are not disease specific, this often leads to late detection, an advanced disease state, and the need fo...

    Authors: Taryne Chong, Amila Sarac, Cindy Q. Yao, Linda Liao, Nicola Lyttle, Paul C. Boutros, John M. S. Bartlett and Melanie Spears

    Citation: Journal of Ovarian Research 2018 11:27

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  36. Content type: Research

    PCOS is a leading endocrinopathy of young women instigating androgens elevation, insulin resistance, obesity, cardiometabolic and menstrual complications. The study investigated the effects of quercetin in a l...

    Authors: Sarwat Jahan, Abira Abid, Sidra Khalid, Tayyaba Afsar, Qurat-Ul-Ain, Ghazala Shaheen, Ali Almajwal and Suhail Razak

    Citation: Journal of Ovarian Research 2018 11:26

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  37. Content type: Research

    Hyperandrogenism and insulin resistance may be related to the etiology of PCOS. Zucker fa/fa rats with polycystic ovary are obese, have insulin resistance without diabetes mellitus or hyperandrogenism and can ...

    Authors: Miyuki Morishita, Toshiaki Endo, Tsuyoshi Baba, Yoshika Kuno, Keiko Ikeda, Tamotsu Kiya, Hiroyuki Honnma and Tsuyoshi Saito

    Citation: Journal of Ovarian Research 2018 11:24

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  38. Content type: Research

    Highly Individualized Egg Retrieval (HIER), defined as age-specific early oocyte retrieval (ER), has been demonstrated to avoid premature luteinization in women ≥43. We here investigated whether HIER also appl...

    Authors: Yan-Guang Wu, David H. Barad, Vitaly A. Kushnir, Qi Wang, Lin Zhang, Sarah K. Darmon, David F. Albertini and Norbert Gleicher

    Citation: Journal of Ovarian Research 2018 11:23

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  39. Content type: Research

    The recurrence, metastasis and poor prognosis are important characteristics of ovarian carcinoma (OC), which are associated with exfoliation of cells from the primary tumor and colonization of the cells in pel...

    Authors: Ji Pang, Pengcheng Jiang, Ying Wang, Lu Jiang, Hai Qian, Yan Tao, Ruxia Shi, Jizong Gao, Yongchang Chen and Yan Wu

    Citation: Journal of Ovarian Research 2018 11:22

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  40. Content type: Research

    The purpose of this retrospective study was to determine the prognosis of non-serous epithelial ovarian cancer (EOC) patients with exclusively retroperitoneal lymph node (LN) metastases, and to compare the pro...

    Authors: Hanifi Sahin, Mehmet Mutlu Meydanli, Mustafa Erkan Sari, Ibrahim Yalcin, Gonca Çoban, Nazlı Topfedaisi Ozkan, Zeliha Firat Cuylan, Baki Erdem, Kemal Gungorduk, Özgür Akbayir, Murat Dede, Mustafa Coşkun Salman, Tayfun Güngör and Ali Ayhan

    Citation: Journal of Ovarian Research 2018 11:21

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  41. Content type: Research

    Extracellular vesicles (EVs) are considered as a new class of resources for potential biomarkers. We analyzed expression of specific mRNA and miRNA in EVs derived from ovarian cancer ascites and the ideal cont...

    Authors: Cindy M. Yamamoto, Melanie L. Oakes, Taku Murakami, Michael G. Muto, Ross S. Berkowitz and Shu-Wing Ng

    Citation: Journal of Ovarian Research 2018 11:20

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  42. Content type: Research

    Metformin influences insulin receptor signaling, which might interfere with the proliferation of ovarian follicular structures and steroidogenesis. We hypothesize that reductions in glucose and insulin levels ...

    Authors: Roberta Rassi Mahamed, Carla Cristina Maganhin, Gisela Rodrigues Silva Sasso, Manuel de Jesus Simões, Maria Candida Pinheiro Baracat, Edmund Chada Baracat and José Maria Soares- Jr

    Citation: Journal of Ovarian Research 2018 11:18

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  43. Content type: Research

    High cyclooxygenase (COX)-2 expression in ovarian tumors has been associated with poor prognosis, but the role of COX-1 expression and its relation to survival is less clear. Here, we evaluated COX expression ...

    Authors: Alicia Beeghly-Fadiel, Andrew J. Wilson, Spencer Keene, Meral El Ramahi, Shu Xu, Lawrence J. Marnett, Oluwole Fadare, Marta A. Crispens and Dineo Khabele

    Citation: Journal of Ovarian Research 2018 11:17

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