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  1. Content type: Research

    Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between neoplasms can be unique, allowing for distinctions in...

    Authors: Julie A. MacDonald, Niharika Kura, Carleigh Sussman and Dori C. Woods

    Citation: Journal of Ovarian Research 2018 11:89

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  2. Content type: Review

    Ovarian cancer has emerged as one of the leading cause of gynecological malignancies. So far, the measurement of CA125 and HE4 concentrations in blood and transvaginal ultrasound examination are essential ovar...

    Authors: Agata Swiatly, Szymon Plewa, Jan Matysiak and Zenon J. Kokot

    Citation: Journal of Ovarian Research 2018 11:88

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  3. Content type: Research

    Fibroblast growth factor 13 (FGF13) is one of the most highly expressed FGF family members in adult mouse ovary. However, its precise roles in ovarian function remain largely unknown. We sought to evaluate the...

    Authors: Yu Liu, Shengxian Li, Tao Tao, Xiaoxue Li, Qinling Zhu, Yu Liao, Jing Ma, Yun Sun and Wei Liu

    Citation: Journal of Ovarian Research 2018 11:87

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  4. Content type: Case report

    Ovarian cancer is the second most common gynecologic malignancy. As the primary imaging modality, computed tomography (CT) can provide staging information for preoperative planning and determination of surgica...

    Authors: Yi-ren Jin, Xie-lan Yang, Qin-qing Li, Zhi-ling Yan, Hong-ying Yang and Chengde Liao

    Citation: Journal of Ovarian Research 2018 11:86

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  5. Content type: Research

    Patients with ovarian cancer represent a heterogeneous population with a variable prognosis and response to chemotherapy. Plasma DNA has been shown to have a prognostic value in different types of cancer inclu...

    Authors: Katarina Kalavska, Tomas Minarik, Barbora Vlkova, Denisa Manasova, Michaela Kubickova, Andrej Jurik, Jozef Mardiak, Jozef Sufliarsky, Peter Celec and Michal Mego

    Citation: Journal of Ovarian Research 2018 11:85

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  6. Content type: Research

    Current methods for determining superior embryo quality (morphological assessment) are unable to compensate for poor pregnancy outcomes. Due to the importance of the cumulus-oocyte complex and the value of cum...

    Authors: Azucena Ocampo, Jeimy Pedraza, Ginna Ortiz, Elizabeth Hernández-Pérez, Leonardo Porchia and Esther López-Bayghen

    Citation: Journal of Ovarian Research 2018 11:84

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  7. Content type: Research

    Very small embryonic-like stem cells (VSELs) exist in adult organs, express pluripotent markers and have the ability to differentiate into three germ layers in vitro. Testicular, ovarian and hematopoietic stem/pr...

    Authors: Kreema James, Deepa Bhartiya, Ranita Ganguly, Ankita Kaushik, Kavita Gala, Pushpa Singh and S. M. Metkari

    Citation: Journal of Ovarian Research 2018 11:83

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  8. Content type: Case report

    11β-hydroxylase deficiency (11OHD) is extremely rare, and reports of non-classical 11OHD are even rarer. Non-classical 11OHD usually presents as premature adrenarche, hyperandrogenism, menstrual disorders, and...

    Authors: Dongdong Wang, Jiahui Wang, Tong Tong and Qing Yang

    Citation: Journal of Ovarian Research 2018 11:82

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  9. Content type: Research

    microRNAs (miRNAs) stably exist in circulating blood encapsulated in extracellular vesicles such as exosomes; therefore, serum miRNAs have the potential to serve as novel cancer biomarkers. New diagnostic mark...

    Authors: Masaki Kobayashi, Kenjiro Sawada, Koji Nakamura, Akihiko Yoshimura, Mayuko Miyamoto, Aasa Shimizu, Kyoso Ishida, Erika Nakatsuka, Michiko Kodama, Kae Hashimoto, Seiji Mabuchi and Tadashi Kimura

    Citation: Journal of Ovarian Research 2018 11:81

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  10. Content type: Research

    The aim of this study was to evaluate the effect of the co-administration of probiotic and selenium on parameters of mental health, hormonal profiles, and biomarkers of inflammation and oxidative stress in wom...

    Authors: Mehri Jamilian, Shirin Mansury, Fereshteh Bahmani, Zahra Heidar, Elaheh Amirani and Zatollah Asemi

    Citation: Journal of Ovarian Research 2018 11:80

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  11. Content type: Case report

    Ovary enlargement is common in controlled ovarian stimulation, which could continue several months during a successful pregnancy. However, persistent megalocystic ovaries 3 years after ovarian hyperstimulation...

    Authors: Jinghua Shi, Xinyu Ren, Qinjie Tian, Aijun Sun and Rong Chen

    Citation: Journal of Ovarian Research 2018 11:79

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  12. Content type: Research

    In some in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles, we may consider transferring one poor-quality embryo with one good-quality embryo. Previous studies have indicated that t...

    Authors: Jiaheng Li, Mingze Du, Zhan Zhang, Yichun Guan, Xingling Wang, Xiao Zhang, Jing Liu, Zhouhui Pan, Bijun Wang and Wenxia Liu

    Citation: Journal of Ovarian Research 2018 11:78

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  13. Content type: Case report

    The mortality rate of ovarian cancer is the highest among all gynecological malignancies in Japan. Ovarian tumors are classified as benign, borderline malignant, or malignant. Anticipating the histological sub...

    Authors: Toshiyuki Okumura, Etuo Muronosono, Masahiko Tsubuku, Yasuhisa Terao, Satoru Takeda and Masanori Maruyama

    Citation: Journal of Ovarian Research 2018 11:77

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  14. Content type: Case report

    The aim of this report was to describe a case of pregnancy after drug-free in vitro activation (IVA) of follicles and fresh tissue autotransplantation in primary ovarian insufficiency (POI) patient and to revi...

    Authors: F. Fabregues, J. Ferreri, J.M. Calafell, V. Moreno, A. Borrás, D. Manau and F. Carmona

    Citation: Journal of Ovarian Research 2018 11:76

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  15. Content type: Case report

    It is well known that ovarian mature cystic teratomas (MCTs) occasionally go through malignant transformations. Among these, approximately 75% of histological types are squamous cell carcinoma, with the other ...

    Authors: Kazuya Maeda, Yoshito Terai, Shinichi Terada, Hiroshi Maruoka, Yuhei Kogata, Keisuke Ashihara, Yoshimichi Tanaka, Tomohito Tanaka, Hiroshi Sasaki, Satoshi Tsunetoh, Takashi Yamada and Masahide Ohmichi

    Citation: Journal of Ovarian Research 2018 11:74

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  16. Content type: Research

    To investigate MRI for differentiating benign from malignant sex cord-stromal tumors of the ovary (SCSTs) emphasizing on the value of diffusion-weighted (DW) magnetic resonance (MR) imaging.

    Authors: Shu-Hui Zhao, Hai-Ming Li, Jin-Wei Qiang, Deng-Bin Wang and Hua Fan

    Citation: Journal of Ovarian Research 2018 11:73

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  17. Content type: Research

    Radiation exposure is known to cause accelerated aging and damage to the ovary, but the contribution of indirect versus direct effects is not well understood. We used the Small Animal Radiation Research Platfo...

    Authors: Allison R. Grover, Bruce F. Kimler and Francesca E. Duncan

    Citation: Journal of Ovarian Research 2018 11:72

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  18. Content type: Research

    In vitro maturation (IVM) has some advantages over conventional in vitro fertilization (IVF), particularly in polycystic ovary syndrome (PCOS) where the risk of ovarian hyperstimulation is high. We studied the...

    Authors: V. N. A. Ho, T. D. Pham, A. H. Le, T. M. Ho and L. N. Vuong

    Citation: Journal of Ovarian Research 2018 11:70

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  19. Content type: Research

    Ageing, socioeconomic level, obesity, fertility, relaxed natural selection and urbanization have been postulated as the risk factors of ovarian cancer (OC56). We sought to identify which factor plays the most ...

    Authors: Wenpeng You, Ian Symonds and Maciej Henneberg

    Citation: Journal of Ovarian Research 2018 11:68

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  20. Content type: Research

    Synchronous endometriosis has been poorly studied in women with endometrioid borderline ovarian tumors (EBOTs). The aims of this study were to compare the clinicopathological features and prognosis of EBOTs wi...

    Authors: Wen Zhang, Shuangzheng Jia, Yang Xiang, Junjun Yang, Congwei Jia and Jinhua Leng

    Citation: Journal of Ovarian Research 2018 11:67

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  21. Content type: Review

    Reproductive aging is a natural process that occurs in all women, eventually leading to reproductive senescence and menopause. Over the past half century there has been a trend towards delayed motherhood. Post...

    Authors: Rani Fritz and Sangita Jindal

    Citation: Journal of Ovarian Research 2018 11:66

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  22. Content type: Research

    In recent years, autotransplantation of cryopreserved ovarian tissue became a promising approach to preserve female fertility. The slow freezing is the most effective technique which resulted in greater live b...

    Authors: Dmitry Nikiforov, Valentina Russo, Delia Nardinocchi, Nicola Bernabò, Mauro Mattioli and Barbara Barboni

    Citation: Journal of Ovarian Research 2018 11:65

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  23. Content type: Research

    Ovarian cancer is the most lethal of gynecological malignancies. Fourier Transform Infrared (FTIR) spectroscopy has gradually developed as a convenient, inexpensive and non-destructive technique for the study ...

    Authors: Lei Li, Xiaoning Bi, Hengzi Sun, Simiao Liu, Mei Yu, Ying Zhang, Shifu Weng, Limin Yang, Yanan Bao, Jinguang Wu, Yizhuang Xu and Keng Shen

    Citation: Journal of Ovarian Research 2018 11:64

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  24. Content type: Research

    In the recent years, vitamin D has become a topical subject and a focus of research not only in reproductive medicine but across many medical disciplines. In reproductive medicine, studies have identified an a...

    Authors: Soheila Arefi, Gholamreza Khalili, Homa Iranmanesh, Fattaneh Farifteh, Ahmad Hosseini, Human M. Fatemi and Barbara Lawrenz

    Citation: Journal of Ovarian Research 2018 11:62

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  25. Content type: Research

    To demonstrate the use of surface-enhanced Raman spectroscopy (SERS) to determine sialic acid (SA) levels in saliva using silver nanoparticles as substrates, in adnexal mass patients scheduled for surgical int...

    Authors: José de Jesús Zermeño-Nava, Marco Ulises Martínez-Martínez, Ana Laura Rámirez-de-Ávila, Aida Catalina Hernández-Arteaga, Ma. Guadalupe García-Valdivieso, Alondra Hernández-Cedillo, Miguel José-Yacamán and Hugo Ricardo Navarro-Contreras

    Citation: Journal of Ovarian Research 2018 11:61

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  26. Content type: Research

    This study sought to clarify the roles of Anti-müllerian hormone (AMH) and follicle stimulating hormone (FSH) in predicting live birth, especially in patients with discordant AMH and FSH. A large IVF data set ...

    Authors: Shunping Wang, Yi Zhang, Virginia Mensah, Warren J. Huber III, Yen-Tsung Huang and Ruben Alvero

    Citation: Journal of Ovarian Research 2018 11:60

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  27. Content type: Research

    Improvements in vitrification and frozen embryo transfer (FET) technologies have rapidly increased, and some evidence suggests that FET may increase pregnancy rates and lead to more favourable perinatal outcom...

    Authors: Junwei Zhang, Mingze Du, Zhe Li, Lulu Wang, Jijun Hu, Bei Zhao, Yingying Feng, Xiaolin Chen and Lijun Sun

    Citation: Journal of Ovarian Research 2018 11:59

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  28. Content type: Research

    Ovarian clear cell carcinoma is a distinct histologic subtype with grave survival. The underlying molecular mechanism is not fully elucidated. However, we don’t have many cell lines, which are useful experimen...

    Authors: Wei Jiang, Shuang Ye, Libing Xiang, Wentao Yang, Tiancong He, Xuan Pei, Lin Guo and Huijuan Yang

    Citation: Journal of Ovarian Research 2018 11:58

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  29. Content type: Research

    Primary cytoreductive surgery followed by adjuvant chemotherapy is the standard treatment for advanced epithelial ovarian cancer. The average interval between surgery and chemotherapy initiation is approximate...

    Authors: Yooyoung Lee, Alexandra Kollara, Taymaa May and Theodore J. Brown

    Citation: Journal of Ovarian Research 2018 11:56

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  30. Content type: Research

    PCOS is a reproductive hormonal abnormality and a metabolic disorder. It is frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, and oxidative stress. We aim to investigate th...

    Authors: Selenay Furat Rencber, Sema Kurnaz Ozbek, Ceyla Eraldemır, Zehra Sezer, Tugba Kum, Sureyya Ceylan and Elif Guzel

    Citation: Journal of Ovarian Research 2018 11:55

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  31. Content type: Research

    This study was to determine age-specific impact of fertility preserving surgery on disease-specific survival in women with stage I borderline ovarian tumors (BOTs). Patients diagnosed during 1988–2000 were sel...

    Authors: Haiyan Sun, Xi Chen, Tao Zhu, Nanfang Liu, Aijun Yu and Shihua Wang

    Citation: Journal of Ovarian Research 2018 11:54

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  32. Content type: Research

    Considered as the precursor lesion of a subset of ovarian clear cell carcinoma (OCCC), the prognostic role of endometriosis in OCCC patients remains controversial. This study aimed to investigate the prognosti...

    Authors: Ting Zhao, Yu Shao, Yan Liu, Xiao Wang, Luyao Guan and Yuan Lu

    Citation: Journal of Ovarian Research 2018 11:53

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  33. Content type: Case Report

    Alpha-fetoprotein (AFP) is a useful tumor marker for ovarian germ cell tumors, particularly yolk sac tumor (YST). It is valuable for both diagnosis and further follow-up. Epithelial ovarian carcinoma (EOC) rar...

    Authors: Wei-Ting Chao, Chia-Hao Liu, Chiung-Ru Lai, Yi-Jen Chen, Chi-Mu Chuang and Peng-Hui Wang

    Citation: Journal of Ovarian Research 2018 11:52

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  34. Content type: Research

    Menopause is the most important sign of aging in women, and the ovary is the organ most sensitive to aging. Quercetin is a potential antioxidant and free radical scavenger that is widely found in fruits, veget...

    Authors: Jiao Wang, Xin Qian, Qiang Gao, Chunmei Lv, Jie Xu, Hongbo Jin and Hui Zhu

    Citation: Journal of Ovarian Research 2018 11:51

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  35. Content type: Review

    Treatment for advanced ovarian cancer is rarely curative; three quarters of patients with advanced disease relapse and ultimately die with resistant disease. Improving patient outcomes will require the introdu...

    Authors: Mary Ellen Gee, Zahra Faraahi, Aiste McCormick and Richard J. Edmondson

    Citation: Journal of Ovarian Research 2018 11:50

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  36. Content type: Research

    The treatment of newly diagnosed advanced epithelial ovarian cancer (EOC) was predicted by an ovarian cancer computed tomography (CT) evaluation model combined with serum CA125.

    Authors: Lu Qin, Huming Huang, Mengjie Chen, Yuejuan Liang and He Wang

    Citation: Journal of Ovarian Research 2018 11:49

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  37. Content type: Research

    The clinical treatment of ovarian cancer with ascites is problematic. The main reasons for treatment failure are the susceptibility to intraperitoneal metastasis and chemotherapeutic drug resistance. The purpo...

    Authors: Duanyang Liu, Dan Kong, Jing Li, Lei Gao, Di Wu, Yu Liu, Weiwei Yang, Lei Zhang, Jiang Zhu and Xiaoming Jin

    Citation: Journal of Ovarian Research 2018 11:47

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  38. Content type: Research

    To assess and compare the influence of three fibroid treatment options: supracervical hysterectomy, ulipristal acetate and uterine artery embolization on ovarian reserve.

    Authors: Piotr Czuczwar, Anna Stepniak, Pawel Milart, Tomasz Paszkowski and Slawomir Wozniak

    Citation: Journal of Ovarian Research 2018 11:45

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  39. Content type: Case report

    Although cases of cervical squamous cell carcinoma metastatic to the ovary have been previously documented, we report the first case of superficially invasive squamous cell carcinoma metastatic to the ovary.

    Authors: Minfen Zhang, Elena Lucas, Hanzhen Xiong, Shaoyan Liu, Kyle Molberg, Qingping Jiang and Wenxin Zheng

    Citation: Journal of Ovarian Research 2018 11:44

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  40. Content type: Research

    Ovarian cancer is the major cause of death among gynecologic cancers with 75% of patients diagnosed with advanced disease, and only 20% of these patients having a survival duration of five years. Treatments bl...

    Authors: Maureen L. Drakes, Swati Mehrotra, Monica Aldulescu, Ronald K. Potkul, Yueying Liu, Anne Grisoli, Cara Joyce, Timothy E. O’Brien, M. Sharon Stack and Patrick J. Stiff

    Citation: Journal of Ovarian Research 2018 11:43

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  41. Content type: Research

    Optimal cytoreduction (macroscopic Residual Tumor, RT = 0) is the best survival predictor factor in epithelial ovarian cancer (EOC). It doesn’t exist a consolidated criteria to predict optimal surgical resecti...

    Authors: Eleonora Ghisoni, Dionyssios Katsaros, Furio Maggiorotto, Massimo Aglietta, Marco Vaira, Michele De Simone, Gloria Mittica, Gaia Giannone, Manuela Robella, Sofia Genta, Fabiola Lucchino, Francesco Marocco, Fulvio Borella, Giorgio Valabrega and Riccardo Ponzone

    Citation: Journal of Ovarian Research 2018 11:42

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  42. Content type: Research

    To analyze the clinical characteristics and chemo-resistance related factors of patients with resistant and non-resistant endometriosis-associated ovarian cancer (ovarian clear cell carcinoma and endometrioid ...

    Authors: Tong Ren, Ting-Ting Sun, Shu Wang, Jian Sun, Yang Xiang, Keng Shen and Jing-He Lang

    Citation: Journal of Ovarian Research 2018 11:40

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