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  1. Content type: Research

    The purpose of this study was to examine proliferative and apoptotic activity in relation with BRCA1 expression in ovarian epithelial inclusions (OEIs), the putative precursor lesions of ovarian epithelial can...

    Authors: Yiying Wang, Yue Wang, Li Wei, Shuhui Hong, Miaoqing Zhao, Xi Zhang and Wenxin Zheng

    Citation: Journal of Ovarian Research 2017 10:12

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  2. Content type: Research

    The mechanism of aggressive character of ovarian cancer and unsuccessful treatment of women with this deadly disease has been recently explained by the theory of cancer stem cells (CSCs). It has been reported ...

    Authors: Natasa Kenda Suster, Spela Smrkolj and Irma Virant-Klun

    Citation: Journal of Ovarian Research 2017 10:11

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  3. Content type: Research

    MicroRNAs (miRNAs) regulate the expression of genes involved in various cellular functions related to metabolism, inflammation, and reproduction. This study evaluated the effects of sex hormones and obesity on...

    Authors: Weixi Xiong, Ying Lin, Lili Xu, Amin Tamadon, Shien Zou, Fubo Tian, Ruijin Shao, Xin Li and Yi Feng

    Citation: Journal of Ovarian Research 2017 10:10

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  4. Content type: Research

    It has long been appreciated that different subtypes (serous, clear cell, endometrioid and mucinous) of epithelial ovarian carcinoma (EOC) have distinct pathogenetic pathways. However, clinical management, esp...

    Authors: Mengjiao Li, Haoran Li, Fei Liu, Rui Bi, Xiaoyu Tu, Lihua Chen, Shuang Ye and Xi Cheng

    Citation: Journal of Ovarian Research 2017 10:9

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  5. Content type: Research

    Glycosphingolipids are important compounds of the plasma membrane of mammalian cells and a number of them have been associated with malignant transformation and progression, reinforcing tumour aggressiveness a...

    Authors: Tatiana Pochechueva, Shahidul Alam, Andreas Schötzau, Alexander Chinarev, Nicolai V. Bovin, Neville F. Hacker, Francis Jacob and Viola Heinzelmann-Schwarz

    Citation: Journal of Ovarian Research 2017 10:8

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  6. Content type: Research

    The aim of our study was to investigate the clinical features and expression levels of hypothalamic-pituitary-gonadal axis-related hormone receptors in low-grade serous ovarian cancer (LGSC).

    Authors: Zheng Feng, Hao Wen, Xingzhu Ju, Rui Bi, Xiaojun Chen, Wentao Yang and Xiaohua Wu

    Citation: Journal of Ovarian Research 2017 10:7

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  7. Content type: Research

    Our objective was to explore the impact of a single dose of an aromatase inhibitor (letrozole) administered at defined times of the follicular phase or immediately after ovulation on dominant follicle developm...

    Authors: H.C.M. Allaway, D.R. Chizen, G.P. Adams and R.A. Pierson

    Citation: Journal of Ovarian Research 2017 10:6

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  8. Content type: Research

    Ovarian transplantation is a useful method for preserving the fertility of young women with cancer who undergo radiotherapy and chemotherapy. Follicle-stimulating hormone (FSH) is use to protect transplanted o...

    Authors: Wen-Zhi Ma, Xiao-Min Zheng, Chang-Chun Hei, Cheng-Jun Zhao, Sha-Sha Xie, Qing Chang, Yu-Fang Cai, Hua Jia, Xiu-Ying Pei and Yan-Rong Wang

    Citation: Journal of Ovarian Research 2017 10:5

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  9. Content type: Research

    A standard histomorphometric approach has been used for nearly 40 years that identifies atretic (e.g., dying) follicles by counting the number of pyknotic granulosa cells (GC) in the largest follicle cross-sec...

    Authors: Bahar Uslu, Carola Conca Dioguardi, Monique Haynes, De-Qiang Miao, Meltem Kurus, Gloria Hoffman and Joshua Johnson

    Citation: Journal of Ovarian Research 2017 10:3

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  10. Content type: Research

    IVF cycles which result in only one good quality embryo, and a second poor quality embryo present a dilemma when the decision involves transferring two embryos. The aim of this study was to evaluate whether a ...

    Authors: Eliana Muskin Wintner, Anat Hershko-Klement, Keren Tzadikevitch, Yehudith Ghetler, Ofer Gonen, Oren Wintner, Adrian Shulman and Amir Wiser

    Citation: Journal of Ovarian Research 2017 10:2

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  11. Content type: Research

    Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women of reproductive age. The study was commenced to assess the favorable effects of Rutin against metabolic, biochemical, histological...

    Authors: Sarwat Jahan, Faryal Munir, Suhail Razak, Anam Mehboob, Qurat Ul Ain, Hizb Ullah, Tayyaba Afsar, Ghazala Shaheen and Ali Almajwal

    Citation: Journal of Ovarian Research 2016 9:86

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  12. Content type: Research

    No consensus exists on the outcome-related factors of interval debulking surgery (IDS) in patients with advanced high-grade serous ovarian cancer (HG-SOC) who underwent neoadjuvant chemotherapy (NAC). This stu...

    Authors: Xia Xu, Fei Deng, Mengmeng Lv, Binhui Ren, Wenwen Guo and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2016 9:85

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  13. Content type: Research

    Key features of advanced ovarian cancer include metastasis via cell clusters in the abdominal cavity and increased chemoresistance. Resveratrol and derivatives of resveratrol have been shown to have antitumour...

    Authors: Alexandria B. Tino, Kenny Chitcholtan, Peter H. Sykes and Ashley Garrill

    Citation: Journal of Ovarian Research 2016 9:84

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  14. Content type: Research

    Ovarian serous carcinoma (OSC) is the most common ovarian epithelial malignancy. Disregulation of Eph/ephrin signaling has been implicated in oncogenesis and tumor progression. EphA5 receptor is one of large f...

    Authors: Xiao Chen, Xuan Wang, Xue Wei and Jiandong Wang

    Citation: Journal of Ovarian Research 2016 9:83

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  15. Content type: Research

    Recent researches demonstrate that pre-treatment with androgen could increase retrieved oocytes number and clinical pregnancy rate in poor ovarian response (POR) patients. In view of gap junction intercellular...

    Authors: Yangyang Zhang, Yang Xu, Yanrong Kuai, Sheng Wang, Qing Xue and Jing Shang

    Citation: Journal of Ovarian Research 2016 9:82

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  16. Content type: Research

    Ovarian thecoma-fibroma groups (OTFG) are uncommon sex cord-stromal neoplasms. The objective of the study was to demonstrate clinical and sonographic features of OTFG and compare with surgical histopathology.

    Authors: Hui Chen, Yan Liu, Li-fei Shen, Mei-jiao Jiang, Zhi-fang Yang and Guo-ping Fang

    Citation: Journal of Ovarian Research 2016 9:81

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  17. Content type: Research

    Ovarian cancer (OC) was the primary malignant gynecological cancer and SNARE protein is closely related with tumor progression. Here, we identified SNAP23, a member of SNARE complex, as a potential oncogene in...

    Authors: Qi Sun, Xing Huang, Quanli Zhang, Junwei Qu, Yang Shen, Xin Wang, Haijun Sun, Jie Wang, Lin Xu, Xiaoxiang Chen and Binhui Ren

    Citation: Journal of Ovarian Research 2016 9:80

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  18. Content type: Case report

    Pseudocarcinomatous hyperplasia of the fallopian tube is a rare, benign disease characterized by florid epithelial hyperplasia.

    Authors: Nam Kyung Lee, Kyung Un Choi, Ga Jin Han, Byung Su Kwon, Yong Jung Song, Dong Soo Suh and Ki Hyung Kim

    Citation: Journal of Ovarian Research 2016 9:79

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  19. Content type: Research

    to investigate the value of using preoperative neutrophil to lymphocyte and platelet to lymphocyte levels in the patients of borderline ovarian tumors.

    Authors: Ghanim Khatib, Cenk Soysal, Cihan Çetin, Ümran Küçükgöz Güleç, Ahmet Barış Güzel, Nadi Keskin, Mehmet Ali Vardar and Derya Gümürdülü

    Citation: Journal of Ovarian Research 2016 9:78

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  20. Content type: Retraction Note

    Authors: Ali Mohammad Bahrami, Fariba Khaki, Shahram Zehtabian, Javad Cheraghi, Mehdi Rashnavadi, Mohammad Reza Hafezi Ahmadi, Mostafa Naderafif, Soheil Javaherypour, Siamak Mohsenzadeh, Ehsan Hosseini, Hamed Masoudi and Mehdi Pourzaer

    Citation: Journal of Ovarian Research 2016 9:77

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    The original article was published in Journal of Ovarian Research 2014 7:105

  21. Content type: Retraction Note

    Authors: Fariba Khaki, Javad Javanbakht, Samieh Sharifzad, Mohammad Javad Gharagozlou, Farshid Khadivar, Javad Yaghoobi Yeganeh Manesh, Seyed Hojjat Hosseini, Ali Anissian, Seyed Rashid Touni, Alireza Gilvari and Fatemeh Soghra Abdi

    Citation: Journal of Ovarian Research 2016 9:76

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    The original article was published in Journal of Ovarian Research 2014 7:33

  22. Content type: Research

    Synuclein gamma (SNCG) expression is associated with advanced disease and chemoresistance in multiple solid tumors. Our goal was to determine if SNCG protein expression in ovarian cancer was correlated with cl...

    Authors: Anna Strohl, Kristina Mori, Stacey Akers, Wiam Bshara, Barbara Buttin, Peter J. Frederick, Irene B. Helenowski, Carl D Morrison, Kunle Odunsi, Julian C. Schink, Denise M. Scholtens, Jian-Jun Wei and J. Julie Kim

    Citation: Journal of Ovarian Research 2016 9:75

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  23. Content type: Review

    Salpingectomy is largely used in case of hydrosalpinx in infertile women scheduled for assisted reproductive technologies (ART), whereas there is no consensus on its role in absence of hydrosalpinx. The curren...

    Authors: Marco Noventa, Salvatore Gizzo, Carlo Saccardi, Shara Borgato, Amerigo Vitagliano, Michela Quaranta, Pietro Litta, Michele Gangemi, Guido Ambrosini, Donato D’Antona and Stefano Palomba

    Citation: Journal of Ovarian Research 2016 9:74

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  24. Content type: Review

    In 1963 George Mathé announced to the world that he had cured a patient of leukaemia by means of a bone-marrow transplant. Since than much progress has been made and nowadays Hematopoietic Stem Cell Transplant...

    Authors: Maurizio Guida, Maria Antonietta Castaldi, Rosa Rosamilio, Valentina Giudice, Francesco Orio and Carmine Selleri

    Citation: Journal of Ovarian Research 2016 9:72

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  25. Content type: Research

    Janus kinase 3 (JAK3) is a member of the membrane-associated non-receptor tyrosine kinase protein family and is considered predominantly expressed in hematopoietic cells. We previously identified JAK3 as a differ...

    Authors: Kalidou Ndiaye, Amélie Castonguay, Gabriel Benoit, David W. Silversides and Jacques G. Lussier

    Citation: Journal of Ovarian Research 2016 9:71

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  26. Content type: Research

    Despite advances in surgical aggressiveness and conventional chemotherapy, ovarian cancer remains the most lethal cause of gynecologic cancer mortality; consequently there is a need for new therapeutic agents ...

    Authors: Eric D. Thomas, Selene Meza-Perez, Kerri S Bevis, Troy D. Randall, G. Yancey Gillespie, Catherine Langford and Ronald D. Alvarez

    Citation: Journal of Ovarian Research 2016 9:70

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  27. Content type: Research

    Abnormalities in tumor suppressors p14, p16 and p53 are reported in several human cancers. In ovarian epithelial carcinogenesis, p16 and p53 show higher immunohistochemical staining frequencies in malignant tu...

    Authors: Vinicius Duarte Cabral, Marcelle Reesink Cerski, Ivana Trindade Sa Brito and Lucia Maria Kliemann

    Citation: Journal of Ovarian Research 2016 9:69

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  28. Content type: Review

    Although existence of ovarian stem cells (OSCs) in mammalian postnatal ovary is still under controversy, however, it has been almost accepted that OSCs are contributing actively to folliculogenesis and neo-oog...

    Authors: Hossein Yazdekhasti, Zahra Rajabi, Soraya Parvari and Mehdi Abbasi

    Citation: Journal of Ovarian Research 2016 9:68

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  29. Content type: Research

    The mechanisms regulating the function and regression of the corpus luteum (CL) have not yet been elucidated in detail. The regressed CL of cows was previously reported to be filled with unusual vessels like a...

    Authors: Junko Nio-Kobayashi, Kaya Miyazaki, Kazuhisa Hashiba, Kiyoshi Okuda and Toshihiko Iwanaga

    Citation: Journal of Ovarian Research 2016 9:67

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  30. Content type: Research

    The optimal surgical management and staging of borderline ovarian tumors (BOTs) are controversial. Institutions have different surgical approaches for the treatment of BOTs. Here, we performed a retrospective ...

    Authors: Mehmet Gokcu, Kemal Gungorduk, Osman Aşıcıoğlu, Nilüfer Çetinkaya, Tayfun Güngör, Gonca Pakay, Zeliha Fırat Cüylan, Tayfun Toptaş, Ramazan Özyurt, Elif Ağaçayak, Aykut Ozdemir, Onur Erol, Anıl Turan, Varol Gülseren, Mehmet Sait İcen, Taylan Şenol…

    Citation: Journal of Ovarian Research 2016 9:66

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  31. Content type: Research

    Multiple drug resistance (MDR) of cancer cells is the main reason of intrinsic or acquired insensitivity to chemotherapy in many cancers. In this study we used ovarian cancer model of acquired drug resistance ...

    Authors: Radosław Januchowski, Karolina Sterzyńska, Katarzyna Zaorska, Patrycja Sosińska, Andrzej Klejewski, Maciej Brązert, Michał Nowicki and Maciej Zabel

    Citation: Journal of Ovarian Research 2016 9:65

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  32. Content type: Research

    Ovarian failure (OF) is considered premature if it occurs before the age of 40.

    Authors: Sylvie Jaillard, Linda Akloul, Marion Beaumont, Houda Hamdi-Roze, Christele Dubourg, Sylvie Odent, Solène Duros, Nathalie Dejucq-Rainsford, Marc-Antoine Belaud-Rotureau and Célia Ravel

    Citation: Journal of Ovarian Research 2016 9:63

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  33. Content type: Research

    A previous study showed that dopamine (DA), which is contained in follicular fluid (FF) from IVF patients, strongly increased the production of reactive oxygen species (ROS) by cultured human granulosa cells (...

    Authors: J. Blohberger, T. Buck, D. Berg, U. Berg, L. Kunz and A. Mayerhofer

    Citation: Journal of Ovarian Research 2016 9:62

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  34. Content type: Research

    The aim of this study is to evaluate a new tumour marker, HE4, and to compare it with CA125 in predicting optimal cytoreduction and response to chemotherapy. Thirty patients with advanced epithelial ovarian ca...

    Authors: Aurélie Pelissier, Aurélie Roulot, Béatrice Guéry, Claire Bonneau, Dominique Bellet and Roman Rouzier

    Citation: Journal of Ovarian Research 2016 9:61

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  35. Content type: Research

    The reduced expression of the Adenomatous polyposis coli (APC) gene, a tumor suppressor gene, through promoter hypermethylation has been reported to play a key role in the carcinogenesis. However, the correlation...

    Authors: Chunyan Shen, Qifang Sheng, Xiaojie Zhang, Yuling Fu and Kemiao Zhu

    Citation: Journal of Ovarian Research 2016 9:60

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  36. Content type: Research

    Because higher survival of follicles during the freezing/thawing procedure improves the quality of cryopreserved tissue reimplanted after oncological therapies, defining an optimal method for human ovarian tis...

    Authors: D. Scheiner, G. Bracone, P. Imesch, D. Fink, J. Hehl and B. Imthurn

    Citation: Journal of Ovarian Research 2016 9:59

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  37. Content type: Research

    Pre-clinical studies have demonstrated that natural and synthetic histone deacetylase (HDAC) inhibitors can impede the in vitro and in vivo growth of cell lines from a variety of gynecologic and other malignan...

    Authors: Leslie A. Garrett, Whitfield B. Growdon, Bo R. Rueda and Rosemary Foster

    Citation: Journal of Ovarian Research 2016 9:58

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  38. Content type: Research

    Ovarian cancer has the highest mortality rate of the three main malignant tumors of the female reproductive system, with a 5-year overall survival (OS) of only 20–30 %. Approximately 70 % of patients relapse w...

    Authors: Zhi-jun Yang, Bing-bing Zhao and Li Li

    Citation: Journal of Ovarian Research 2016 9:57

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  39. Content type: Research

    Previous studies have shown that circadian genes might be involved in the development of polycystic ovarian syndrome (PCOS). Hyperandrogenism is a hallmark feature of PCOS. However, the effect of hyperandrogen...

    Authors: Minghui Chen, Yanwen Xu, Benyu Miao, Hui Zhao, Lu Luo, Huijuan Shi and Canquan Zhou

    Citation: Journal of Ovarian Research 2016 9:56

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  40. Content type: Research

    Experience on sentinel node mapping in ovarian tumors is very limited. We evaluated the sentinel node concept in ovarian tumors using intra-operativeTc-99m-Phytate injection and lymphoscintigraphy imaging.

    Authors: Malihe Hassanzadeh, Elham Hosseini Farahabadi, Zohreh Yousefi, Sima Kadkhodayan, Leili Zarifmahmoudi and Ramin Sadeghi

    Citation: Journal of Ovarian Research 2016 9:55

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  41. Content type: Case report

    Resistant ovary syndrome (ROS) is a rare endocrine disorder characterized with hypergonadotrophic hypogonadism. Infertility is a common complaint of woman presenting with ROS, and little progress has been made...

    Authors: Yu Li, Ping Pan, Ping Yuan, Qi Qiu and Dongzi Yang

    Citation: Journal of Ovarian Research 2016 9:54

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  42. Content type: Research

    To investigate the expression of MMP-14 and CD44 as well as epithelial-to-mesenchymal transition(EMT)-like changes in ovarian cancer and to determine correlations with clinical outcome.

    Authors: Maria Caroline Vos, Eva Hollemans, Nicole Ezendam, Harry Feijen, Dorry Boll, Brenda Pijlman, Hans van der Putten, Paul Klinkhamer, Toin H. van Kuppevelt, Anneke A. M. van der Wurff and Leon F. A. G. Massuger

    Citation: Journal of Ovarian Research 2016 9:53

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  43. Content type: Research

    As we have previously reported, small cell carcinoma of the ovary (SCCO) is a rare, aggressive form of ovarian cancer associated with poor outcomes. In an effort to identify new treatment options, we utilized ...

    Authors: George Yaghmour, Philippe Prouet, Eric Wiedower, Omer Hassan Jamy, Rebecca Feldman, Jason C Chandler, Manjari Pandey and Mike G Martin

    Citation: Journal of Ovarian Research 2016 9:52

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  44. Content type: Research

    There are various parameters to analyze obesity, however, no standard reference to predict, screen or diagnose PCOS with various obesity parameters has been established, and the accuracy of these parameters st...

    Authors: Pan Dou, Huiyan Ju, Jing Shang, Xueying Li, Qing Xue, Yang Xu and Xiaohui Guo

    Citation: Journal of Ovarian Research 2016 9:51

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  45. Content type: Research

    Ovarian tissue cryopreservation is an emerging technique, also addressed to very young cancer patients, for whom it is not possible to perform an ovarian stimulation for oocytes freezing, before gonadotoxic tr...

    Authors: Raffaella Fabbri, Maria Macciocca, Rossella Vicenti, Gianandrea Pasquinelli, Giacomo Caprara, Sabrina Valente, Renato Seracchioli and Roberto Paradisi

    Citation: Journal of Ovarian Research 2016 9:50

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