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Ovarian cancer (OC) can occur at different ages ... risk of cardiovascular mortality in patients with ovarian cancer, we included influencing factors including age, ... on cardiovascular death events in patients ...
Target-driven cancer therapy is a notable advancement in precision ... been accompanied by substantial medical accomplishments. Ovarian cancer is a highly frequent neoplasm in women ... aimed at identifying speci...
Omentectomy is an important procedure in surgery for epithelial ovarian cancer, but the scope of omentectomy is not ... of infragastric omentectomy in patients with epithelial ovarian cancer.
Macrophages play an essential role in regulating ovarian cancer immune microenvironment. Studies have shown that m6A methylation could influence immune microenvironment in cancer. In this study, we investigated t...
Ovarian cancer, among all gynecologic malignancies, exhibits the ... early stages. For the advancement of Ovarian Cancer Diagnosis, it is crucial to identify the ... further as a diagnostic biomarker for detectin...
To establish a prognostic risk profile for ovarian cancer (OC) patients based on cancer-associated fibroblasts (CAFs) and gain a...
IR emerges as a feature in the pathophysiology of PCOS, precipitating ovulatory anomalies and endometrial dysfunctions that contribute to the infertility challenges characteristic of this condition. Despite it...
Our explorative study assessed a panel of molecules for their association with epithelial ovarian carcinomas and their prognostic implications. The panel included tissue expression of VEGF-C, COX-2, Ki-67 and ...
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women that necessitates effective and safe treatment alternatives. This study aimed to evaluate the therapeutic efficacy of Vitex negundo seed i...
Umbilical cord-derived mesenchymal stem cell (UCMSC) transplantation has been deeply explored for premature ovarian insufficiency (POI) disease. However, the associated mechanism remains to be researched. To e...
Ovarian cancer is a leading cause of death among ... and increased lipid biosynthesis are key factors driving cancer cell growth. Stearoyl-CoA desaturase 1 ( ... expression and significance of SCD1 in epithelial ...
Polycystic ovarian syndrome (PCOS) is the most common endocrine disease in women of childbearing age which is often associated with abnormal proliferation or apoptosis of granulosa cells (GCs). Studies proved tha...
Ovarian cancer remains the deadliest of the gynecologic cancers in the United States. There have been ... drug conjugate (anti-STn-ADC) in ovarian cancer.
This retrospective study aims to evaluating the subsequent management and outcomes after first-line PARPi progression in Chinese ovarian cancer population.
Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic condition in women of childbearing age and a major cause of anovulatory infertility. The pathophysiology of PCOS is complex. Recent studi...
The gene cell division cycle associated 5 (CDCA5), also called sororin, has oncogenic characteristics and is upregulated in various carcinomas. Nevertheless, the involvement of CDCA5 in ovarian cancer (OC), a hig...
Premature ovarian insufficiency (POI) is a severe disorder leading to female infertility. Genetic mutations are important factors causing POI. TP63-truncating mutation has been reported to cause POI by increas...
Quiescin sulfhydryl oxidase 2 (QSOX2) is a flavin adenine dinucleotide-dependent sulfhydryl oxidase that is known to be involved in protein folding, cell growth regulation, and redox state modification through...
It is well described that circulating progesterone (P4) plays a key role in several reproductive events such as oocyte maturation. However, during diestrus, when circulating P4 is at the highest concentrations...
Ovarian cancer (OC) is a severe gynecological malignancy ... and therapeutic challenges. The discovery of reliable cancer biomarkers can be used to adjust diagnosis...
Premature ovarian failure (POF) is a devastating condition for women under 40 years old. Chemotherapy, especially the use of cisplatin, has been demonstrated to promote the apoptosis of granulosa cells in prim...
Lymph node metastasis (LNM) is a major factor contributing to the high mortality rate of ovarian cancer, making the treatment of this disease challenging ... , the molecular mechanism underlying LNM in ovarian cancer
Follitropin delta is a novel recombinant follicle stimulating hormone preparation uniquely expressed in a human fetal retinal cell line by recombinant DNA technology. To date, no systematic review was availabl...
To investigate the clinical and magnetic resonance imaging (MRI) features for preoperatively discriminating primary ovarian mucinous malignant tumors (POMTs) and metastatic mucinous carcinomas involving the o...
Tumors are highly heterogeneous, and within their parenchyma, a small population of tumor-stem cells possessing differentiation potential, high oncogenicity, and self-renewal capabilities exists. These cells are ...
Mesonephric-like adenocarcinoma is a new class of rare subtypes of the female reproductive system. Its clinical symptoms are similar to other types of ovarian tumors. The diagnosis is based on pathological and...
The efficacy of subsequent therapy after poly-ADP-ribose polymerase (PARP) inhibitor maintenance treatment has raised concerns. Retrospective studies show worse outcomes for platinum-based chemotherapy after prog...
Ovarian cancer is the eighth leading cause of cancer-related death among women, characterized by late ... PARP inhibitors (PARPi) in treating advanced ovarian cancer.
Despite receiving first-line treatment, ovarian cancer patients continue to experience a high rate of recurrence; nearly all women with ovarian cancer develop chemoresistance and succumb to the disease. In this s...
Individual patients with ovarian cancer show remarkably different prognosis. Present prognostic models for ovarian cancer mainly focus on clinico-pathological parameters, so ... are urgently needed. Platelets con...
Ovarian cancer is a significant challenge in women's ... worldwide. Recent research has shown that ovarian cancer has an "iron addiction" phenotype which ... targeted inhibitors with GPX4-targeted inhibitors in o...
Despite advances in medical imaging technology, the accurate preoperative prediction of lymph node status remains challenging in ovarian cancer. This retrospective study aimed to investigate the ... ) in patients...
This study aims to investigate the effects of natural products on animal models of premature ovarian failure (POF).
To construct a machine learning diagnostic model integrating feature dimensionality reduction techniques and artificial neural network classifiers to develop the value of clinical routine blood indexes for the au...
Polycystic ovary syndrome (PCOS) is a gynecological endocrine disease and could be considered a metabolic disease because it is often accompanied by obesity and insulin resistance. Brown adipose tissue (BAT) t...
To investigate the effects of metformin (MET) monotherapy and pioglitazone plus MET (PIOMET) therapy on gonadal and metabolic profiles in normal-weight women with polycystic ovary syndrome (PCOS).
Mucin 16 (MUC16) overexpression is linked with cancer progression, metastasis, and therapy resistance in high grade serous ovarian cancer and other malignancies. The cleavage of MUC16 ... which circulates as a pr...
Poor ovarian response (POR) is a big challenge for in vitro fertilization. The traditional Chinese medicine, Cai’s Prescription of Tonifying Kidney and Strengthening Vitals (Cai’s Prescription) has yielded sat...
Ovarian clear-cell cancer is a rare subtype of epithelial ovarian cancer with unique clinical and biological features. Despite ... trials to advance treatment for ovarian clear-cell cancer. Immediate progress is ...
PCOS is a widespread disease that primarily caused in-pregnancy in pregnant-age women. Normoandrogen (NA) and Hyperandrogen (HA) PCOS are distinct subtypes of PCOS, while bio-markers and expression patterns fo...
The present study aimed to explore the maternal and perinatal risks in cases of monozygotic twins (MZT) following frozen-thawed embryo transfer (FET).
Ovarian cancer (OC) is the most lethal gynecologic...
This case series is the first report regarding ovarian stimulation with oocyte cryopreservation in younger than 18 years cancerous girls, who refer to ROYAN institute, Tehran, Iran, prior to the start of the trea...
The etiology of premature ovarian insufficiency, that is, the loss of ovarian activity before 40 years of age, is complex. Studies suggest that genetic factors are involved in 20–25% of cases. The aim of this ...
Ovarian cancer is the most lethal gynecologic neoplasm, and ... the promising immunotherapy showed limited efficacy in ovarian cancer, probably due to the immunosuppressive microenvironment. ... the immune exclus...
Polycystic Ovary Syndrome (PCOS) affects a significant proportion of human females worldwide and is characterized by hormonal, metabolic, and reproductive dysfunctions, including infertility, irregular menstru...
Ovarian cancer (OC) is one of the most...N-glycome has been observed in many diseases, while the association between serum protein N...-glycosylation and OC progression remains unclear, particularly for the onset...
Bushen Tiaoxue Granules (BTG) is an empirical Chinese herbal formula that has been used for the treatment of subfertility. The protective effect of BTG on controlled ovarian hyperstimulation (COH)-induced impa...
Premature ovarian failure (POF) is a leading cause of women’s infertility without effective treatment. The purpose of this study was to investigate the protective effects of Luffa cylindrica fermentation liquid (...
The mechanisms and risk factors underlying ovarian cancer (OC) remain under investigation, making the...
2022 Citation Impact
4.0 - 2-year Impact Factor
4.7 - 5-year Impact Factor
1.118 - SNIP (Source Normalized Impact per Paper)
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